AA_substitution(s)	competitive_growth_score	stderr
Subset 1	nan	nan
A10G	0.545178577564802	0.276260289202912
A129V	-0.106306006463229	0.0525687372752477
A131S	0.971831487406141	0.327676264180179
A150T	0.0687325513507252	0.265307000251999
A150W	0.45104001152728	0.0959802615480267
A152D	-0.0860028290300852	0.0824985562921451
A152T	0.0868700893687614	0.139412134804559
A156T	0.993518202014233	0.223065964447003
A156V	0.387068566163276	0.0582195864555604
A15V	0.763496904925282	0.334290282412438
A5G	1.07938820229417	0.103867843567964
C138R	0.845550357417584	0.0581962088997585
C138Y	0.26520880771169	0.109969810314975
C75K	0.0291888131804175	0.076659040212181
C75R	-0.0272695282836566	0.0356676422054054
C93R	-0.303716824237473	0.0501647531642315
C93S	-0.24833334920164	0.0738400656660538
C93Y	0.0500654295402636	0.117091932718857
D100G	0.207548620429472	0.0798245717623928
D102G	1.58707052669515	0.118719004437875
D102N	0.387737550195573	0.0846475813207533
D127G	-0.374402343246329	0.0791927302148508
D127V	-0.385486253164348	0.0856290624287828
D33G	0.0571055620581851	0.0561081428099364
D33V	-0.195755650389424	0.123268397933137
E118G	0.752800129515783	0.0703868832440468
E118K	0.650491496031679	0.0643542991932006
E118V	0.762905164224114	0.102603945834215
E122G	0.52193002994401	0.0540469409920255
E122K	0.450994654378191	0.0710717830817612
E122L	0.494880041002366	0.048160608619434
E122R	0.705511814183207	0.0308222003018368
E122S	0.424846952004813	0.260896285911788
E122T	1.02918390770292	0.125146762595045
E122W	0.425140331206943	0.0620680603273971
E12G	0.161245013861224	0.0969374598048105
E132D	1.05958246471293	0.150319136890367
E132G	0.494727720233715	0.106985623193709
E143G	0.187031486267298	0.0535428317039833
E145G	0.252862669353624	0.0833818023516145
E145K	0.218322464844165	0.106272523482087
E145Q	1.13116781908707	0.245140855346273
E145V	0.362383421115828	0.0849657079535496
E42G	0.589110805101798	0.031265996624857
E42V	0.545921946914115	0.0816558162507673
E54G	0.76829638849844	0.172502258589865
E78G	0.908079675658313	0.0380969313954116
E98G	2.22636912819321	0.257439719566921
E99G	0.0797281463280613	0.208510043149443
F155S	0.609438056835162	0.0197822864648417
F155Y	0.595422607865079	0.22926059469754
F58L	0.394663774364432	0.197500947002189
F64I	0.974164053242162	0.0732943486190858
F64L	0.633629232751452	0.0634806818006487
F77S	-0.197822909067501	0.123850098323221
F82L	0.0353494566191011	0.087636445997818
G115E	0.184975130131295	0.105644581245979
G34I	0.375882014177588	0.13320923229237
G3R	0.191870065430707	0.0580223013970643
G55E	0.860330858500007	0.0663061300365597
G90R	0.311198862402836	0.230503238248378
H20P	0.0105336121989017	0.0559549740987001
H83R	-0.0170690870928357	0.0623824085469353
I107N	1.45460534274525	0.0878198603177964
I107T	0.153330905138575	0.174845691597514
I107V	1.1000569627622	0.0503053219605987
I109L	0.630022255170231	0.141149032534165
I109N	0.0752512559950823	0.0510901401584346
I109R	0.117432759360583	0.0851720919683044
I109T	0.25801980367144	0.0571766427321815
I112A	0.0621897387690581	0.0822749114219219
I112T	1.82671754132147	0.0996223294489435
I112V	0.775292828207392	0.0450338547216468
I116M	1.71269024526249	0.0309388347645022
I116T	0.719975908603232	0.275709392981583
I116V	0.886904293986936	0.125130039494299
I125F	NA	NA
I125R	-0.220115590096426	0.115255615768886
I125T	0.874672139031929	0.146628984003059
I125V	0.115799194724927	NA
I136T	0.446878887591263	0.0448293104755123
I45T	0.622569969881855	0.125307584173784
I45V	1.50179803312662	0.0645230841990141
I4T	-0.400926090348922	0.163455007545204
I96L	1.04379712493386	0.0685806465644021
I96T	1.53910091954816	0.24399945587583
I96V	1.46587647365751	0.0693677111257046
K101E	0.826056251545198	0.0623711847608479
K101R	1.35099642784964	0.0643987441505682
K110E	0.388892684259474	0.169006782516031
K110R	0.894503730420998	0.0780994292653797
K110T	-0.18798820645795	0.110230793415566
K146E	0.617308106095973	0.0401083924791922
K146R	1.08827561862108	0.141095913748497
K14R	1.28914572756706	0.0382856082158847
K153E	1.15336452989013	0.0952668651819214
K153R	1.22252662840098	0.112962980020511
K154E	0.642946420923238	0.271441772267625
K18R	1.08764760423717	0.0327737919183215
K48R	1.06412621708552	0.0774048248636621
K49E	1.02872823046804	0.112465568592407
K49N	0.792613260376029	0.156968485687451
K59E	0.831131545532507	0.152790839148546
K59N	0.577635005374877	0.0330316689718201
K59R	0.00894062804292901	0.123717311815879
K65E	1.06222734414385	0.208827208403072
K65N	1.68031060265561	0.0738029762591254
K65R	1.45262990332261	0.0299214338587442
K74E	1.42351578697905	0.318747020643748
K74R	-0.335362470844773	0.18487203783554
K74S	1.74794429259386	0.181991276574447
K76E	0.760295367528415	0.0890978353652107
K76R	0.984634145869251	0.044707451382917
K76T	0.988269821243572	0.0921280199175034
L113Q	-0.0162203835238677	0.152506268951954
L113V	0.61763844533866	0.15954972806646
L114I	0.507761567709341	0.157770299609276
L114S	1.12592055712274	0.404318694345738
L119P	-0.0536217550185887	0.044248196539539
L119R	-0.0691576927842799	0.104701787116684
L120P	0.0044774664992443	0.0704121448253114
L38R	0.0243966184291062	0.075045923486318
L38V	0.367362616712675	0.0339043024363686
L60P	0.521794073490965	0.307902545953895
L63V	1.20419271569917	0.132427328431698
L94P	-0.355233738776286	0.122960478636413
L94Q	NA	NA
L97I	1.73758795454651	0.0689714159342886
L97S	0.36234804966907	0.0557894434439867
L9P	0.0378801967331159	0.0717648185175513
M36T	0.292146544748869	0.265770392569248
M39V	0.930517720768749	0.113667705583372
M62I	0.425375914664679	0.142380742435124
M62V	0.862129595280408	0.0767325288545809
N121D	0.858636872805758	0.0708789846049069
N121I	0.159181473800141	0.156400303632477
N121S	0.815336042109982	0.145909248115456
N121Y	0.619671564983088	0.0222710336855382
N124K	-0.168344652785188	0.072467992668418
N124R	-0.0676647885866577	0.0783482578094701
N124S	0.0440657509776658	0.0452911979987442
N140D	0.714763205552469	0.167279034724298
N140S	0.138164487737648	0.126482812183582
N37S	0.912746100576407	0.0956988090982772
N85D	-0.0423131462970813	0.0513466021307011
P123E	-0.114763458759389	0.0615755346853778
P157L	1.01976744998362	0.271984490974022
P157S	0.578089727558967	0.0350715840496314
P28Q	0.0015931717425098	0.239069906480011
P32S	1.29102979185996	0.09487240304838
P52L	0.49129316779305	0.0502339145765802
P73L	0.029427419847459	0.0884438539880514
P84L	0.97624151296806	0.0417293174152607
P84S	0.0643762794271922	0.0895301231165177
P88L	1.29168321327428	0.0403961141612017
P88S	1.19709313481242	0.109662463396942
Q111H	0.629786186003663	0.384048497685675
Q111P	0.841928362300336	0.393175492378083
Q117L	0.506430703638945	0.113842499892906
Q117R	0.475376074614436	0.144190290760203
Q126H	0.19286322665924	0.104096533298485
Q126L	-0.18206240653781	0.274037368079313
Q126R	0.871033735549063	0.0528248119706358
Q130L	0.275132369685445	0.0835936302490363
Q130R	0.855198013527697	0.141970252806251
Q151R	-0.0426152973411553	0.0554316946384336
R104G	-0.162901182858533	0.103111214038165
R104K	0.134189876629882	0.36331771558492
R13G	-0.0554317707133061	0.0828072400036654
R141G	0.0960570968123371	0.0911220390480892
R141I	1.00480556945564	0.101710178233608
R141T	0.25062030602289	0.119775198692119
R147G	-0.157738181211801	0.0772633454752864
R8G	NA	NA
S158A	0.776812174238952	0.0790032844647018
S158P	1.1563964821355	0.108247379296777
S2L	0.0814047417712138	0.0347909945794211
S2P	-0.216277299202207	0.0306691449799965
S2T	0.788021250968387	0.0541156653879048
S70P	0.149309560323536	0.0921928304283629
S71P	0.225173395176979	0.0365727456198148
S71T	0.466009671937395	0.0519353103094514
S7C	0.408942082751649	0.180879769223527
S89A	1.22255871141135	0.118647838454115
S89L	0.544296902594746	0.142566399182702
S89P	0.448657080121231	0.0775559533637979
S95P	-0.0852711344026769	0.0615102192222533
T108A	1.96161743630228	0.0887215109503497
T135A	0.588441687690598	0.0753840794473758
T135M	0.125689035650807	0.136278458956115
T135S	0.426605702247782	0.0548764478340839
T29A	-0.546166989836066	NA
T35A	0.0658704810896509	0.0581663426944367
T51A	-0.0719235272356401	0.0639503782212494
T91A	1.55486606329814	0.211044336144241
V142A	1.04602377972541	0.175386574227149
V142E	1.67036875428924	0.127707619794732
V148A	0.283902094606765	0.114704718295524
V148D	-0.203283665471811	0.154122562781513
V148L	0.054997106160737	0.0800322631000135
V86A	0.359374991439046	0.0529111771168208
V86M	0.942794586237702	0.0561125200068322
V92A	0.611419880305691	0.0991195398993568
V92E	-0.0250706831015251	0.0605231425725621
W103R	0.0706795662518442	0.0658006028647964
W16R	-0.00790034422650189	0.0651056528911216
W41R	0.111708017825139	0.0581027500576281
Y134F	0.444947984973882	0.167526242868028
Y134N	0.156561608471576	0.0934796260531661
Y137C	0.131061619003891	0.11364388455157
Y137S	-0.144731495335115	0.0851562395863514
Y144C	0.0899086747004464	0.105754379797685
Y144H	NA	NA
Y144S	0.208708725323388	0.131801942691868
Y68C	0.166239799396393	0.0476871994325577
Y68H	0.423701794549898	0.106696901906731
Y87C	0.131080601304502	0.0610512727782025
Y87H	0.317998430129709	0.227545715593526
Y87N	-0.0935998934667481	0.0462722345607606
#Subset 2	nan	nan
A106I	-0.16666677142575	0.154109886103039
A106L	0.521500235040644	0.124614035093383
A106M	NA	NA
A106P	0.160717601175238	0.114251721302933
A106T	0.941936103995756	0.105920099863813
A106V	0.567753276611355	0.273839759706908
A106Y	0.243372086642079	0.0335961099762685
A10S	NA	NA
A10T	0.292252795043884	0.115174879026379
A10V	0.399089102325182	0.0928823577966181
A129G	0.236009074952338	0.0815370052815318
A131G	NA	NA
A131L	0.627803333266106	0.102735804082964
A131P	0.333997529895568	0.142873238785075
A131R	-0.282704106592066	0.120964975824286
A131T	1.31382812566798	0.163784090730014
A131V	0.523989006006165	0.387075632816423
A131Y	0.615308547175857	0.112325488465458
A133M	-0.179437243639553	0.119108379515097
A133T	-0.295694375057533	0.160733761725595
A133V	0.400018324925363	0.124247238521219
A150K	0.723008443032589	0.143297791558389
A150S	NA	NA
A150V	0.753840477943385	0.163853371637158
A152G	-0.107503718735903	0.242541254196658
A152V	0.227924664162653	0.118243049950831
A152Y	-0.0552663952997116	0.0994457289456086
A156G	-0.352372149279389	0.220598380324373
A15D	1.830749553565	0.150472781113469
A15P	0.0916919369948423	0.149575256383048
A26P	0.108455685920989	0.102068255188771
A26V	0.0476095864486233	0.102574308581464
A44T	0.267973037054783	0.14286598564531
A5T	0.36567336131947	0.110977161240414
A5V	0.874638681992864	0.113031990112961
C138F	0.413236252050689	0.107020101030023
C138S	0.721066890907734	0.0723066057154872
C138W	NA	NA
C43R	-0.028968989221734	0.0840383380810992
C43S	0.00207945541390328	0.207409327264658
C43W	0.242316474028877	0.153824711291302
C75G	0.158224630440263	0.107568685479191
C75I	2.58540711425429	0.148147886390586
C75N	-0.000499871345044015	0.122973777794979
C75P	1.32818914293312	0.11446879131113
C75Q	0.242147102230572	0.11827996090957
C75S	0.64261410934447	0.104639282719837
C75T	-0.0890411195822473	0.159636236541004
C75W	-0.105447677778843	0.119275952265404
C93G	-0.536803022663351	0.152839682286354
C93W	-0.221547896720154	0.128748984619028
D100N	0.630200406285755	0.0996805807394002
D100Y	1.23440765593814	0.108032638231065
D127A	-0.132007149839271	0.076396911267637
D127F	-0.435553941829662	0.157465931002539
D127N	0.404201127789288	0.114283385548486
D127S	0.936099689362353	0.436530368765832
D127Y	0.173763372312622	0.169269685071973
D19G	0.0297859912786166	0.105496949265939
D19V	0.090057478839863	0.110014840453534
D33E	0.312472468940265	0.119897417699814
D33H	NA	NA
D33N	0.53918427237945	0.117427442065577
D66E	1.72979732658842	0.178107152865657
D66G	0.525633396619013	0.0663780946672352
D66R	0.541048152139546	0.155927526928958
D66V	-0.0343826857757746	0.119936734926944
D67E	0.9533217944553	0.0988011895044932
D67L	0.393501598491072	0.108016911011863
D67N	0.617675040508031	0.106590285011381
D67Q	NA	NA
D67T	0.100849268047754	0.136821334480927
D67V	0.140606510060417	0.101128295426796
D67W	-0.0778509529323923	0.184614280712241
D67Y	0.192216004314358	0.107644047366468
E118L	0.424597336606323	0.122776798788605
E118N	NA	NA
E118P	0.322668076831583	0.11547726981444
E118S	0.27038553386018	0.114468170807023
E118Y	0.552817406933181	0.113384855049821
E122A	NA	NA
E122C	0.75147032884342	0.190402871520134
E122D	0.555121448449928	0.169661251469796
E122F	NA	NA
E122I	0.401050506551294	0.10566683544854
E122Q	1.18070630452215	0.10816567609181
E122V	0.744896373103895	0.114589556703553
E12Q	0.521662205945481	0.114482764299076
E132L	0.0952187230147651	0.120932001286179
E132S	0.253320903633705	0.122461626209727
E132V	0.317441959577519	0.101261204670435
E143I	0.609172394397402	0.105139698878861
E143V	0.483453648181239	0.111611726211356
E143Y	0.263189239179136	0.101366915657225
E145F	0.37501214364045	0.118847818607858
E54K	0.256044599659624	0.161982814662469
E54V	0.799638773582557	0.160850327788193
E78R	NA	NA
E78T	1.29192829056775	0.221159076065718
E78V	1.0604704014796	0.322705824164601
E98K	1.19739524069704	0.088187333117581
E98V	-0.0478115751454624	0.136634963999506
E99D	1.22262882907343	0.103009275875983
E99Q	0.589151758273104	0.325420995068475
F155C	0.420490330231165	0.106863025410217
F155L	0.556396811226355	0.0184178132446566
F22I	NA	NA
F22L	0.104365210919323	0.0394256922045557
F22S	0.344616010345889	0.189198144165104
F22Y	0.787839445218774	0.0398174288240955
F24L	0.0643815563071036	0.168888051724309
F24S	0.384515060081784	0.164678417350503
F58S	0.0705653233590358	0.0595835459586643
F64S	-0.126225635991799	0.0579646184828858
F64V	0.830318340813654	0.107413764806418
F77I	0.210354393260716	0.071682406774771
F77L	0.350497581765176	0.084721060100426
F77N	-0.010598917568548	0.0856077069954185
F77P	0.359856296472222	0.113593714681561
F77T	-0.150287088515042	0.119649366318015
F77V	0.119800318459506	0.158788276678693
F82H	0.305691274861487	0.116492528903498
F82K	-0.0327697405474754	0.127523871381503
F82N	0.167207794739503	0.247451866999727
F82R	-0.114851563503254	0.183972335617132
F82S	0.024762473672629	0.11024818972813
G115K	-0.00885674550523302	0.133486045702483
G115R	NA	NA
G115S	-0.266920763642282	0.139604520522263
G115V	0.330472965200846	0.201147171387602
G23D	-0.000863998732441669	0.185149982162048
G23S	NA	NA
G34C	0.335396664509821	0.169707511876851
G34D	0.568048000561241	0.106273836967029
G34M	0.132989784573079	0.122070914490402
G34V	-0.0278352646922518	0.117585459653919
G3E	0.716539791039543	0.170304753918728
G47E	NA	NA
G55N	0.0180655656704914	0.307536526555511
G55Q	0.587402597302359	0.106350649731919
G55R	0.369463983833742	0.134020802726969
G55S	0.190738059448328	0.11662655567074
G56F	-0.0906907967385567	0.108501505531057
G56S	0.150331356228304	0.107293354769255
G90E	-0.0229443998176188	0.104639467204362
G90W	-0.00311080246350357	0.0249516120111288
H20L	NA	NA
H20R	-0.209479020125152	0.466877023764686
H83L	0.1303023803252	0.101269923818602
H83M	-0.777749484937338	0.175104360039631
H83Q	0.0702563323036324	0.079482601657459
H83Y	-0.104211355335234	0.115928383170322
I107A	NA	NA
I107C	1.41048513320518	0.136952905854842
I107F	0.883391139975981	0.242734802415292
I107L	1.3176614413315	0.108976598752165
I107S	1.09395505381893	0.11255863235403
I109E	0.0817742866300954	0.237312963442873
I109K	0.147767388848299	0.112700591617362
I109S	-0.044543602962936	0.0834277534191322
I109V	0.688511221281351	0.0418202028652527
I112M	1.56567874247227	0.103750095807904
I112R	-0.0111372555126246	0.191374323122188
I116K	-0.172738967195089	0.116733830673803
I116L	2.46050387193691	0.13134582686601
I116R	0.0361088352447382	0.0601794262286015
I125A	0.563933253498809	0.0540493493937939
I125L	0.748335529362564	0.110707203180467
I125N	0.596998989969968	0.0469915368261284
I125S	0.651383816913083	0.17035089095123
I125W	0.77216322736008	0.136522198000758
I136F	0.966933986991184	0.162517855798938
I136N	1.20864985994151	0.210311532335375
I136Q	0.940306566419488	0.108250242334215
I136V	0.229354824807928	0.100549286185042
I45F	-0.174697731393337	0.148864300503821
I45H	0.186919827908696	0.123896672578738
I4G	0.382828168623207	0.109649316400447
I4L	NA	NA
I4N	NA	NA
I96C	NA	NA
I96G	0.142223512835401	0.152375503608651
I96S	1.11915187374004	0.144337640755447
K101T	0.705629073267329	0.155898694411355
K101Y	2.16764884787143	0.107534026737415
K110A	-0.0864269747366362	0.0774697350863451
K110H	0.505852279894949	0.105170875172225
K110L	0.24457024488023	0.0513579189195605
K110N	0.509651880056243	0.115454544068839
K110V	0.661905548704229	0.104713592435353
K146L	0.429479168326823	0.110859200927691
K146N	0.464936830567033	0.127290170242267
K14T	0.119681658882448	0.125002790373388
K154A	0.763521090003642	0.111675954952716
K154L	0.717878204000071	0.254507743755143
K154Q	0.83657926521086	0.0992607501312475
K154R	0.866691020444319	0.101669942014294
K154T	1.66509724498362	0.2197051297295
K154V	1.23846112361903	0.105373644296953
K18E	NA	NA
K18L	NA	NA
K18V	0.995119106792997	0.107283971867766
K18Y	0.211430744029111	0.064678341686623
K30R	NA	NA
K48E	0.205265812815642	0.110732139546615
K48T	0.439288347597328	0.103264164140121
K49A	0.89074665329768	0.100107234183079
K59I	0.306438790880422	0.0669443147850061
K65Q	0.761580294446228	0.106492502524953
K74A	1.50755016735574	0.204810651213586
K74D	NA	NA
K74H	1.85158952819529	0.104596334071675
K74M	0.729134333254372	0.219889520514786
K74P	0.0606058545171546	0.103500574947542
K76D	1.75564697110908	0.0556700595272649
K76I	1.21099381603159	0.104221892548482
K76N	1.51220512926125	0.122079454805191
K76P	0.226880912738533	0.165156251694105
K76S	0.414672086429685	0.277283537352234
L113A	0.568091488869857	0.124368304191507
L113C	1.14945950071653	0.123743431476939
L113F	NA	NA
L113I	1.07340426792249	0.123688511136846
L113P	0.593687641496278	0.099924709611417
L113R	-0.189205842447281	0.0688612013639061
L113S	0.424790020268803	0.0755417991500111
L113T	-0.52689291757608	0.255165962485266
L114F	1.21171652416743	0.377492741106317
L114G	0.884979195099887	0.203280552219501
L114H	0.869803625699699	0.0903910758040272
L114K	0.12347130807275	0.190908874102424
L114T	0.974471276053467	0.119548479190132
L114Y	0.986315335508033	0.109722384207361
L119A	0.172814469617183	0.118948920154959
L119C	0.196368638006022	0.109473707738086
L119G	-0.0697093251299157	0.156089889788857
L119S	NA	NA
L120D	0.0143977684799085	0.115218323491019
L120F	NA	NA
L120H	-0.0269885917950128	0.171860995471981
L120N	-0.166555672492305	0.145152085268125
L120Q	-0.109497780291314	0.132102823028809
L120S	0.0447927565012693	0.0711249800697051
L38H	-0.22068871347199	0.0692954917750615
L38I	0.620981916886392	0.0998591613836549
L38P	0.294324317259578	0.127033452717905
L57F	0.0755890494008695	0.100858420403503
L57M	0.600030899409692	0.1103975383805
L57S	0.207165050219801	0.0791371014580165
L60I	1.0636106072864	0.094142374551768
L63F	0.796138869414203	0.127855404328296
L63P	0.034981286114639	0.141998986953528
L6H	0.429263975570049	0.24243241825517
L81N	0.0128876887068738	0.0734223861372595
L81S	0.263333362146502	0.20634467503962
L81T	-0.18230360586397	0.116393929099512
L94K	-0.566439182873385	0.130511817239824
L94M	NA	NA
L9H	0.212613959635044	0.119333108785796
M1I	NA	NA
M1T	0.354380990323273	0.186926338306675
M36A	-0.366521283078369	0.15052922904746
M36I	0.239321427161348	0.148865216631231
M36K	0.424184328026148	0.169396721085128
M36L	NA	NA
M36S	-0.537213583395981	0.158522596242503
M36V	0.186204596823267	0.102713336890278
M39K	0.106463833108113	0.115454326643255
M62R	0.0138849392979948	0.106697164292194
M62T	0.466997439210995	0.14266710201732
M62W	0.832716186254237	0.193635779312947
N121A	0.514745628691862	0.159500130450101
N121C	-0.00213674259906363	0.137886727248278
N121E	0.767454885502915	0.100696574260496
N121F	-0.107169671860252	0.132190004632674
N121G	0.279600036945573	0.114885724777398
N121K	NA	NA
N121L	0.567869513597804	0.191133253742792
N121P	-0.0190027006438391	0.157981344046774
N121R	0.713402469173572	0.0997774221410205
N121T	0.752372319917137	0.125585090365087
N124A	0.289330445952177	0.127861080939297
N124C	0.818351727552664	0.123533576029081
N124D	-0.0207122488177171	0.123230032292968
N124H	0.295711336281305	0.120766171996137
N124L	-0.0367843752594306	0.0671472612607611
N124P	-0.269934702611767	0.21364705014526
N140I	0.0284819213982541	0.101776775994066
N140T	0.140885755212277	0.119745197658476
N31C	0.586916328918647	0.102572418149984
N31D	-0.243686267886093	0.119632073223941
N31R	0.297367955418181	0.112031028688789
N31S	1.01010887952087	0.118488716411961
N31Y	0.796113130539177	0.0425670817761875
N37D	1.2261090928723	0.164671915756829
N37K	1.13630633118779	0.121097927131638
N37R	0.582806921244844	0.118236117485529
N37W	NA	NA
N37Y	0.608101716546967	0.123795147062175
N40D	1.36489327490582	0.13406670679838
N40S	1.68413199445917	0.294366257626888
N40Y	0.506701320052307	0.101867331120166
N85H	NA	NA
N85K	-0.0412612532808038	0.238298526516089
N85S	0.741477144176465	0.117177773711329
N85Y	-0.0648224566301634	0.1195803564107
P105E	1.28624298291859	0.110277873661083
P105L	-0.188237624670194	0.213484684770806
P105R	-0.500809985393852	0.227850735713535
P105S	0.653270113190104	0.103159199410926
P105T	NA	NA
P105V	0.10912826608539	0.111260844889162
P123F	-0.191660095036108	0.128966139739988
P123G	-0.10331321510785	0.0761217218739513
P123K	-0.0545445813434325	0.154236950523426
P123L	-0.0749651894850601	0.148147845073438
P123S	0.437835143587233	0.190079469951735
P123T	-0.000331985439964454	0.0612149675755941
P128L	-0.0259405017500477	0.141970253432607
P128S	0.360508870286808	0.135496633564907
P128T	NA	NA
P157A	0.977980399902155	0.145474960956891
P157H	0.198233212515643	0.117153922584902
P157T	NA	NA
P21A	NA	NA
P21S	0.453805555814467	0.105296015558804
P28C	NA	NA
P28L	0.0690814044985816	0.133642802991315
P28S	0.795564987261536	0.107497757719879
P32D	NA	NA
P32L	0.898763433162996	0.0880471089247847
P32T	0.935355303143941	0.169993421256953
P46L	0.454473219160921	0.107829549208681
P46S	0.128692822637871	0.170875822191977
P52D	0.991481143197948	0.108437192485348
P52N	1.23129226909138	0.150202631072292
P69K	-0.404918685498419	0.182415056271466
P69L	0.370724698162723	0.235280360096056
P69R	-0.326232586651429	0.0598774384411957
P69S	0.153703513178657	0.196667897835357
P72C	1.08285731844917	0.121018914281604
P72L	0.936740837763065	0.105172638388576
P72S	NA	NA
P72Y	-0.58640784622561	0.145687231001427
P73Q	0.150986048418225	0.115258993804043
P73S	0.257501589174556	0.211619117748528
P73T	NA	NA
P79L	0.529414814724921	0.109364538864868
P79S	NA	NA
P79Y	1.61338910731519	0.140689887986701
P80A	1.29451585011601	0.11267721010716
P80S	0.14917161156905	0.152462943412188
P88H	1.14264199736622	0.0614795442368325
Q111R	1.15609398566643	0.102325501044776
Q111S	1.77518587587503	0.138397906927272
Q111V	0.93311800012648	0.118942909376179
Q117D	-0.150015627048751	0.162552469794081
Q117E	0.77978518437097	0.189676712856332
Q117G	NA	NA
Q117P	0.722227586924425	0.109876552420756
Q11R	1.01109714028739	0.114698085900397
Q126A	0.242506673395245	0.133854039280162
Q126C	0.966780518986756	0.120409678831076
Q126F	0.472246364543155	0.123401312935722
Q126K	0.38146438329864	0.240381092200353
Q126P	-0.168858532093654	0.0597651832807003
Q126S	NA	NA
Q126T	1.17946543161415	0.107091536776859
Q130H	0.796799721001664	0.111710718937347
Q130P	0.0164140767117138	0.119167921226771
Q130T	NA	NA
Q139H	0.584645795943171	0.134907192153901
Q139K	0.81192176180219	0.101325803650077
Q139L	0.299407106529101	0.184958007953271
Q139R	0.812615676671162	0.195950356927005
Q151L	0.455826672309461	0.102895743500301
Q151S	-0.0132698861322577	0.119363540731813
R104M	0.0758138254311945	0.129969907291189
R104W	-0.205318465068354	0.145274515427969
R13W	NA	NA
R141K	0.157989052391679	0.245026338736753
R141S	0.225977424614464	0.110492917618619
R141W	-0.010954001044962	0.10908021809008
R147L	1.09055802101063	0.139868434856663
R147M	NA	NA
R147N	0.273642109069286	0.14740846583522
R147S	0.82605415416216	0.1009555520124
R149G	0.687644586288664	0.172773595237458
R149Q	0.839724995914122	0.112696967846167
R149Y	0.395138541210291	0.107893051835171
R17K	0.271444108677043	0.120058967458083
R17S	0.260614545102746	0.097789429683682
R61G	0.259813480336871	0.113606086213938
R61P	NA	NA
R61W	-0.0604320544630139	0.0944770286920782
S158L	0.625050533604123	0.0503162905918078
S2A	0.330161795817517	0.156887759911011
S2R	NA	NA
S71L	0.0732687012764986	0.208021361065161
S7G	0.207283155512203	0.0757987023185938
S7I	0.219661411231725	0.10869449747497
S7N	0.799389977921668	0.130551752938248
S7R	NA	NA
S95F	0.0949357069364857	0.113217742124437
S95T	0.463251008590417	0.115103725749094
T108I	1.06234492812773	0.101260862501845
T108L	1.8767174407562	0.105774941765118
T108S	1.01664579307623	0.101949187982334
T108Y	1.90577504749452	0.151028625962862
T29I	0.566935368952473	0.107453715634333
T35P	0.3069700005069	0.111141604123437
T35Y	-0.315166607408682	0.0563285227783053
T51R	0.102516813111784	0.110518125689084
T51S	0.553631442108208	0.104783949045505
T91S	1.77712952148416	0.186132951146096
V142F	0.673884562697729	0.0979394400175706
V142G	0.453735220828178	0.115643140667972
V142H	0.717589558196676	0.148705424711219
V142M	0.127839238883484	0.201016710936945
V142P	0.546960019950923	0.180483195386484
V142S	1.50908590729575	0.106195981792807
V148F	-0.357571394992123	0.163783438676979
V148G	-0.0557231594863914	0.0560760101228042
V148I	1.25293910943808	0.162529534711137
V25A	0.74078905890848	0.219464168789174
V25L	0.465217824216967	0.191433916514038
V25M	0.893707610092856	0.140331730447404
V27A	0.178153562615214	0.067920327543329
V27D	0.16356775379221	0.117984108190623
V27H	1.24311493520341	0.127024777955856
V86E	-0.0615377422642894	0.0675385993664328
V92L	1.3139081717329	0.124812200297593
V92N	-0.196468801921226	0.128544255062439
W103C	-0.19889752664483	0.124412957370422
W103F	1.33755871345512	0.137747040622932
W103G	0.282703017585921	0.108372104405243
W103H	0.252480590933023	0.136635265151845
W16D	0.0100624711505367	0.134794257065058
W16F	0.535913562562951	0.115418668343334
W16I	0.0915665413327497	0.124845934443289
W16K	0.454237007908187	0.193404129229632
W41L	-0.147951884227827	0.122596760214448
W53C	NA	NA
W53G	-0.0356612528512827	0.226367019740041
W53K	-0.133570270726245	0.106835535660671
W53R	0.501695836812756	0.172173242780163
Y134C	NA	NA
Y134H	0.0943165700239958	0.0449588270945079
Y134R	-0.209070684781349	0.148946535094749
Y137F	0.235342475500947	0.219769393756697
Y137H	NA	NA
Y137N	-0.197813983239849	0.0892775195679898
Y137W	0.606204669022427	0.227232773770632
Y144D	1.18255098589002	0.126667882343794
Y144F	-0.368874891197606	0.115931416950362
Y144T	-0.0259302152072823	0.134018369259347
Y68D	-0.301644429047659	0.101220086930364
Y68F	0.522434056700057	0.120290168944108
Y68K	0.180652043267893	0.172438269695037
Y68N	-0.02296183227223	0.182319710435277
Y68Q	-0.223149438969505	0.131317597462579
Y68R	0.271315174402151	0.132338673934518
Y87D	0.200020482305857	0.104673084459782
Subset 3
A106D,E118D	0.154384854295382	0.100832631550995
A106G,I107N,L120P	0.164141904445682	0.116133812043513
A106G,L120P,Q126L	NA	NA
A106L,P123V	NA	NA
A106L,Y134N	-0.269020849696686	0.218746071487658
A106Q,K153E	NA	NA
A106R,V142A	NA	NA
A106S,E122M	0.898682283247651	0.0672959832544578
A106S,E122V,Q151H	-0.0743723925801981	0.110515984321054
A106T,A150L	0.751033016295419	0.0994945505133999
A106T,K110F	0.048088858676863	0.0773822655317269
A106V,I109T,P123T,E132G	NA	NA
A106V,L119P,Y134H,A156V	-0.219812818150791	0.100178183146862
A106V,Q139R	0.520199976806125	0.10381996716317
A106Y,E122V,D127S	0.118573375872422	0.10999488171212
A106Y,N121S	0.0235616717495639	0.123120961189263
A10D,I107F	0.242566300623115	0.1247126535062
A10D,L120V	-0.243592555494343	0.217907392807922
A10D,T91S,I107F,D127G	-0.255755837932431	0.213353249057484
A10G,A15E,M39V,L113I	0.231556721053208	0.103021636592427
A10G,A15T	0.727811882078318	0.180239721849279
A10G,A44G,I45V,K146E	0.686820509599498	0.125562893437946
A10G,D100G	0.273866067286519	0.105122856689808
A10G,D66N,S71P,A133T	NA	NA
A10G,E145G	0.0497917351732101	0.0894086108480658
A10G,E145V	-0.136795282313692	0.216058301437899
A10G,E54D	-0.100121760028211	0.10593264151006
A10G,F22S,I45F,D66E,E118D	-0.366589943863948	0.199516220536477
A10G,F58V,T91A,I109V	1.96267637852037	0.141508201581136
A10G,H83L,T91I,E122D	0.280404873777243	0.225370595314039
A10G,I107T	0.376466784694574	0.0887683423734175
A10G,K154E	0.156924574846976	0.0574944385305498
A10G,K30E,K49R,A150W	NA	NA
A10G,K59E	0.939128901878427	0.192255006482021
A10G,L120P,Y134S	-0.24337625766265	0.192865716358577
A10G,M62V,K74R	0.699093968212837	0.105287148912876
A10G,P21T,L57M,F64S,S71P	NA	NA
A10G,Q11R,P73S	0.506062237385162	0.137036932760012
A10G,Q130R,Q151H	NA	NA
A10G,R17G,S70P,S89P,I96V	-0.513513691838648	0.218522317534734
A10G,R61L,D66N,S71P,I107T,A133T	-0.0444744098855595	0.182450591939941
A10G,S95P,A131V,Q151R	0.157591365915174	0.168583932666176
A10G,T29A,C138R	1.25983800992128	0.228858677609785
A10G,T35A,F58S,K101E,I107T	0.520811764749819	0.232924928970919
A10G,V25A	NA	NA
A10G,V25A,L63P,E99G	0.698303679450966	0.155790923342508
A10N,N31D,G34R,M39T,K74Y,I96L,K101R,R104Q,V148L,K154L	0.29622713362278	0.18725697173965
A10P,N40D	0.367333205390349	0.185982058044561
A10S,D19E,L120A	0.76896637501497	0.124904404976809
A10S,L38H,N85I,I125T	-0.0272512591963532	0.108728534400751
A10S,L94P,L97S	-0.275864815764832	0.113033070457829
A10T,D67G,I96T,I116M,N124Y,Y134C	NA	NA
A10T,K18E,L57S,L97S	0.0658838129088072	0.121671067481329
A10T,K18E,L97S,Y134H,V148D,F155S	0.253634071357768	0.185372601483054
A10T,L114I,A133F,K146E	0.00258285165447494	0.120063008857785
A10T,L38P,C138Y	0.207860081560865	0.21353316484778
A10T,P123F	0.15459004242688	0.104114842325355
A10T,P123L	0.687061266797828	0.107388538143455
A10T,P28T,C138Y,V142E	-0.0111154763449092	0.119754143010718
A10T,P79I	0.87475814209034	0.148426233852335
A10T,P88L	0.781619678961137	0.110146001948355
A10T,R13G,A131T	0.603112796192017	0.174502290392659
A10T,R13G,D33G	0.108713618515486	0.106058484737125
A10T,T35V,K74V,E118F	-0.42984108107636	0.163761744764247
A10T,W16R,L97I,L120P	0.103899567791724	0.105576952695402
A10V,D19G,N40S,F77L,S89P,W103C,K153E	-0.0687599622078959	0.161916864811914
A10V,F82L,P157H	1.12163587292567	0.304844708094458
A10V,N31D	0.450350512089169	0.2321780869088
A10V,N31D,C93S	NA	NA
A129T,A150T	-0.0578770560007855	0.107470279339274
A131I,F155Y	1.05521878344834	0.214060312293378
A131R,C138F	0.00961530301283787	0.117843660253561
A131V,F155Y	0.874825060300052	0.202551273047263
A133F,V142A	0.0128078169597696	0.152711574677021
A133G,V142G	NA	NA
A133T,K146R	0.0825217632069059	0.105903583830896
A150T,P157S	2.10195010765218	0.110038160080088
A152D,K153R	NA	NA
A152G,F155L	-0.140469152026649	0.114794452876854
A15C,W41D,W53G,M62V,Q111R	-0.00224107076135924	0.0481792411694444
A15E,K30R,P46M,P69Q,I96V,I109G,I125P,Y144A	0.284503780646906	0.127120762392635
A15E,M36K,N37D,S95P,T135A	0.367158117089562	0.151769720295129
A15E,M36K,R61Q,F77I,I125P	0.474758936375424	0.187985629030234
A15E,P46M,P69Q,I96V,I109G,I125P,A129S,Y144A	-0.110417241952582	0.115999194559319
A15E,P46M,P69Q,I96V,I109G,I125P,Y144A	-0.143085306595966	0.124593734051625
A15E,P52Y	0.979340554087584	0.108455810555528
A15G,W41D,W53G,M62V,Q111R	0.0796853634258876	0.107209877364087
A15I,G34T,K48N,T51H,H83R	0.212699279664327	0.100614477337674
A15K,D67T,E122F,Y137M	-0.203519654651742	0.102584238167678
A15K,G34I,G50W,E78Q,E98P,A133T,K154L	-0.153918863212968	0.190828268973106
A15K,L63F,V148I	1.1510798785751	0.112636714008401
A15L,G23D,W41R,F77Q,Q126R	-0.44874519059749	0.192437708139368
A15L,R141S	0.911646192203283	0.12834962313256
A15P,I107T	-0.396902340835381	0.293648424734014
A15S,N121Q,E143N	0.246059994826343	0.113983876769305
A15T,F77Y	NA	NA
A15T,K76E	2.57461190501112	0.177128489536955
A15T,K76I	1.32331628103121	0.112817581823903
A15V,E42V,L63F,V86G	0.0355057778116821	0.105779459010747
A15V,E99G,L119P	-0.0985257805480247	0.0653490918657575
A15V,F77Y,Y144H	0.230818827671544	0.104299049168666
A15V,G90R,L113V	0.535452522628276	0.212097458419902
A15V,M39T	1.02248485585744	0.115831887632042
A15V,M62L	-0.133454300030438	0.159481346862071
A15V,N37S,E42V,L97F,P105S,A150V	0.66875620850699	0.127279588698598
A15V,P105C	0.915005176133936	0.105356388012195
A15V,W103S,I107T	-0.319491814009504	0.0708163783975782
A15W,D100G,Q126D	0.356799697507369	0.0991962603805284
A26E,I96Q,G115R	0.0562740982789919	0.111527275047715
A26G,A106T	0.354482543148491	0.0337330811758721
A26G,N31S,F77S,N124I,A150V,Q151R,K154M	0.336166676463114	0.174808670822068
A26G,N31T,D67T,E132P	-0.154809903286367	0.118747743931493
A26G,R147S	0.34825001888479	0.164608131567
A26P,I109T	-0.295592755775518	0.115484711101608
A26P,T29A,E143G	0.181375974129081	0.106199674272972
A26P,V27G,M36T,M39V,D66N,K101E,L119S,A152G	NA	NA
A26R,P52R,P72E,H83Y,K110S,Q126S,V142L,A156M	-7.89825743348491e-05	0.104347512313775
A26S,F64S,A156V	NA	NA
A26S,F64S,Y134C,V142M	-0.13710504097364	0.0607175208500913
A26S,K48E,K65N,C93S	-0.22676614728147	0.163367640935664
A26S,Q126P	0.227234056345913	0.165007265163324
A26T,C75G,I112N,E122P,Y144C	-0.272842233694446	0.122624941779532
A26T,D67G,I112V	NA	NA
A26T,E54G,T108A	-0.220014673814411	0.124876431884092
A26T,I109V	-0.175933553282007	0.101491756109156
A26T,I45V,D66R	-0.0887493625166394	0.144316622402333
A26T,K59E,Q111R	NA	NA
A26T,L63P	0.544787574810655	0.111663801015355
A26V,E143G	-0.0727212805789499	0.188070010126142
A26V,E98G,N124G	-0.084856143704545	0.0709143696324021
A26V,F77S,P84T,E143G	NA	NA
A26V,M39T,F82L,N85D,I112T,R149L	-0.0783531387399968	0.125325273292788
A26V,M39T,S95Y,L113R,V142A,E145K	0.261793681668042	0.187883816207915
A26V,R61S,K74R,I107M	-0.464249190597081	0.161783330750926
A44C,P105R,R141G	0.0791371491863608	0.110517268753582
A44D,L57S,I107T	0.0966044072499507	0.055194837052916
A44P,I107V,E118D,N124S,Q126R,A131S	0.499647613928189	0.190416115336416
A44P,W103R	-0.121217458052939	0.216314556177734
A44S,F58S,V86M,R141G	0.352116982008351	0.208322451398711
A44S,P52S,F64L,S158P	1.34018618324959	0.148918981137921
A44S,V86A,K110R	0.394694840738314	0.0368292322828353
A44T,H83N	0.141017219374176	0.106402240193104
A44T,I45V,P52R	0.964597342028626	0.116768842634996
A44T,P52S,R104G	-0.170049372721924	0.134727769771578
A44T,P80R	0.285176176873376	0.106264056733481
A44T,Y87N,V142A	-0.00947544043210868	0.110198336143701
A44V,A131E	0.366949353466758	0.153579161391356
A44V,E122V	NA	NA
A44V,G115R	-0.451039431488396	0.287513014333227
A44V,K49N,A152G	0.670498216363472	0.209530494037482
A44V,L81N,K110R,D127A,Y137A	-0.0873385292668955	0.141556736103929
A44V,Q139R	0.0108698042515149	0.109847833014706
A44V,S71T	0.477339275145625	0.119154891796525
A44V,Y134C	-0.0755128466145372	0.142833638582109
A5D,F22K,P46L,E122V	NA	NA
A5D,I136F,N140D,K153R	0.746096354525745	0.160656102111909
A5G,A10G	0.575667373858207	0.103002406281189
A5G,A10G,K154E	NA	NA
A5G,A10G,M39T	0.279162970378575	0.0727472359634712
A5G,C93R	-0.258535390650149	0.105806101346582
A5G,D100N,F155L	NA	NA
A5G,F155L	0.354780543341632	0.0639580590865152
A5G,F22Y,T51I	0.430209557154886	0.247841296936033
A5G,G55R,P69L,D127G,I136V,K154R	1.88584945032421	0.175934712212487
A5G,I107T,I136M	-0.413316733113695	0.104242530534878
A5G,I107T,I136M,R147G	0.00810232884035036	0.166793644779788
A5G,I136G	-0.258837435942961	0.150619028080673
A5G,I136V,K154R	2.27417979842397	0.223281627110558
A5G,K14R,V92M,L113R	0.661781578127023	0.200551685212556
A5G,K153E	NA	NA
A5G,K30R,N124Y	0.43185461837719	0.0909611964295432
A5G,L9F,K48R,E78G,Y144D	1.20055970044817	0.242307957890915
A5G,P21S,K48R	NA	NA
A5G,Q130P,Y134C,R141A	0.362233776752788	0.150798832498307
A5G,R104K	0.530634179632114	0.107218563832526
A5G,R13W,W41R	-0.0908014598876248	0.0478282686465972
A5G,R17K	0.747029830376414	0.031018831167069
A5G,R17K,D19G,L60C,P80T	NA	NA
A5G,R17K,F22S,T35A,R104G	0.238966898333215	0.180041707988307
A5G,T29A,L57V,N124S,P128S,Q151L	0.456764971969922	0.181078693211987
A5G,T51A	0.0252517595125729	0.128614016794534
A5G,W53R,K59R,F64S,V86A,R104G,Y137H	0.303657932441979	0.15523222388935
A5G,W53R,R149Q	0.0585223429113302	0.105678080116729
A5G,W53R,V86A	-0.0471781228830245	0.154883722297291
A5G,W53R,V86A,K101R	0.133060519704478	0.154290263667257
A5G,W53R,V92A,R149Q	0.850461387557153	0.108621436935266
A5G,Y68C,E122L,C138W	0.0586829049578177	0.187725998484441
A5P,D66G,Y144H	0.403786771984569	0.099511266398282
A5P,F24L,W53R,L119P,N121D	-0.0685297722327894	0.104976928069654
A5P,K30N,K48R,D66Y,L81A,E98G,A106Y,A131N	0.389797734819948	0.14824095694579
A5P,L38R,L81F,I96V,I107T,N121H	1.19124886872057	0.183327693710639
A5P,L63F,C75V,R104W,Y144H	-0.523682621185246	0.252674286899754
A5P,N40S,E54K,Y137N	0.403586513574629	0.170794483416373
A5P,P84T,E143V,Q151E	0.247270248645703	0.184688473293087
A5S,K74R,A129T	0.239605720857826	0.143047380558935
A5T,F64S,Y134C,V142M	NA	NA
A5T,G50R,F82L	0.0638387361204661	0.117553815479739
A5T,K14I,E54D	0.319444453118472	0.179427292033146
A5T,K14N,V92A,A129S	-0.0253552218452206	0.113363551100555
A5T,K14R,K18R,F24S,M62I,I96T	-0.185432452758769	0.0856001784759396
A5T,K153R	0.901046160486035	0.0506712596145523
A5T,L9F,H20R,M39K	0.0576127890593162	0.199852815194016
A5T,N37S,E132G,V142M	1.00656058373414	0.189370602170977
A5T,N37S,V142M	0.812060973220739	0.116613437399689
A5T,R61L,K65R	0.520747215473676	0.125218162096212
A5T,V27A,T29S,M39L,N40D,E132G	0.782631099479908	0.124284645011682
A5V,K48R,R61Q	0.203908305898777	0.102664273783334
A5V,L113P,L120I,R147Y	1.10709174741032	0.125928055335444
A5V,L120I,R141S	0.291043448733162	0.112798402913452
A5V,M39T,W103R	0.541279438660085	0.172042225036706
A5V,N37S,E99G,K154R	0.0887814227484702	0.109861439743972
A5V,R17G,E118G	-0.147140898125704	0.220935183657421
A5V,W41R,N121H	0.0367455656162896	0.101661766471459
C138R,R149Q	0.42503202925973	0.111695740446806
C138R,V148A	1.10299037213207	0.120747519702584
C138Y,N140R	-0.293829855122209	0.196088139808957
C43R,F58C,E132A,A133T	0.600864680104137	0.136677629916677
C43R,F64S	0.640189069902736	0.252824487588286
C43R,I96T	0.128829536319941	0.106211526645202
C43R,K110E,I136V	-0.0779481117984629	0.0356489026055292
C43R,K48R,V86M,Q111L,I116V,Q117R	-0.168323728692935	0.191755262680437
C43R,K49I,D67N,P79R,E98V,F155L	1.06461939005529	0.114820518234938
C43R,L114K,L120S,A150S	-0.0306012102456616	0.489705720534861
C43R,N121V	0.2081404478428	0.117351415575147
C43R,N140S	-0.201133798874466	0.100438708700156
C43R,P80S	0.0287625954469673	0.184717507472979
C43R,R104S,N121C,Y134H,V142A	0.0494290000173218	0.124153954429011
C43R,R147G	0.216605753680501	0.0959521822427973
C43R,R61G,Y134C,E143G	NA	NA
C43R,S70P,P84R,I96T	0.488075715776032	0.13630601545635
C43R,T51S	0.145944822425589	0.179568560972899
C43S,D67W,P123E,R149T	0.038940609259833	0.117887045210754
C43S,I116M,Y134N	-0.124502193786393	0.191218577352008
C43S,K65E,L119H	NA	NA
C43S,L119M	0.218137037236119	0.145950085397717
C43S,N85S,D100V	NA	NA
C43S,P80L	0.421533066680161	0.259556262401914
C43S,Q126K	NA	NA
C43S,W53R	0.604102911958051	0.217856717015353
C43S,Y134N	NA	NA
C43S,Y68H,Q126P	0.240289513772051	0.154467042536525
C43W,C75R	0.0344382449897566	0.108888167308871
C43W,I109F	-0.159149887401503	0.101193287597327
C43W,P73Q,C93R,R147W,A152G	0.0532891403512978	0.237354009855604
C43Y,E118G,K154R	2.21946575768775	0.194462098010549
C43Y,F64S,P69S,F82S	-0.723239566551239	0.485594445630468
C43Y,K59R,D127G,Q139K	NA	NA
C43Y,L63P,D67G,A129T	0.0738750499649246	0.0937992229646428
C43Y,P72S,L94M,K110E	0.0484968710689309	0.10925754158328
C75A,E122G,D127G,R147K	-0.792746423939779	0.28596776432614
C75A,R147K	0.45724015638921	0.103111975554312
C75D,Q111H	0.183723405487617	0.104824372924038
C75D,T108P	NA	NA
C75F,L114S,T135S	0.207732806357298	0.235620660425618
C75F,N124L	0.187213125135362	0.15311553738645
C75G,N121L,K146E	-0.183167026042306	0.132826143822353
C75H,A133T,E145G	-0.0890935260341409	0.133174665148697
C75H,Q139R	-0.234081692751698	0.109966978844107
C75H,Q151L	0.251365471567792	0.150878515486163
C75K,I107F	0.185765038208387	0.115817014857604
C75L,L119F	2.57477731427988	0.168268493098976
C75L,Q126A	NA	NA
C75N,G115R	0.167655216672339	0.14657747175829
C75P,K76T,L114R	1.04631241616315	0.128860638264072
C75P,L97S	-0.313361900218205	0.143447548576817
C75Q,T135R	0.50453827281108	0.127150456961655
C75R,E145G	NA	NA
C75R,E98G,K110R,N124Y,K153R	0.0297490032038072	0.310805259627266
C75R,F82C	-0.213604707651311	0.136878371660665
C75R,I109V,V148A	-0.329863718316227	0.125026378453717
C75R,K76R,W103R,E122G	0.0454693224612252	0.16284235155231
C75R,L81S	0.0921351525376946	0.101666075886797
C75R,N124V	-0.164116325354603	0.102906932112672
C75R,P157L	0.233624613764084	0.157377275840159
C75R,Q130R	0.149878410011571	0.210603237046866
C75R,Q151A	-0.0179929315129219	0.166065821739173
C75R,W103C	NA	NA
C75S,A106V,I109T,N140D	0.327040158917386	0.208597078409958
C75S,F82L,A106P,L120I	NA	NA
C75S,K110P	0.331089907449801	0.102508124984577
C75S,L119S	0.0753164364412978	0.141455699506607
C75S,N124S	0.662240175943165	0.180406710309159
C75S,P157A	0.510641117022318	0.122145731774407
C75T,E122G	-0.044789086553443	0.13634566018434
C75T,P88S,I136G	0.717757604282382	0.104613931832265
C75T,T135E,N140H	1.80907699831794	0.135615661118121
C75W,T108A	0.0390993243211115	0.167230241197077
C75Y,C93S,L113P	-0.146811424007545	0.0841313733792003
C93G,I112F,I116K,E118W,P123N,V142A,V148G,K154E	NA	NA
C93G,I112F,I116K,P123N,V142S,V148G,K154E	0.291408475004854	0.107087233976092
C93G,K153R	-0.197746846512348	0.132412249727279
C93G,R104L	NA	NA
C93R,E118G	NA	NA
C93R,E118G,K154T	0.0736645354851652	0.167688040408101
C93R,I107V,E122G	-0.306256014261756	0.120708811601326
C93R,I107V,E122G,N140I	-0.0385171711928986	0.184156816688216
C93R,I107V,E122G,V142A	-0.134340005965319	0.120788719548312
C93R,I136V	-0.0806674152355938	0.121790341248542
C93R,K110R	-0.307721577425126	0.260715436257532
C93R,K146E	0.346618821218647	0.163387761365498
C93R,P105G	-0.0393590998603041	0.118200451232895
C93R,T108K	NA	NA
C93S,I107V,Y144N,R147G,A152G	NA	NA
C93S,I125T	0.052321415784754	0.116935470536749
C93W,I116V	NA	NA
C93W,P157L	-0.0293945761891739	0.0922771119202141
C93W,Q151R	-0.268449228182559	0.115197852317354
C93Y,A106T,A156V	-0.181533896218757	0.104334401664536
C93Y,Y137C	0.487688478221451	0.136837852060617
D100G,C138S	0.592918283283716	0.113398788985121
D100G,D102G,V148D,K154R	0.494410835816414	0.108398866217217
D100G,D102N,T108I,E122I,R141S,K154E	0.156213032524702	0.106414999602924
D100G,I136F	1.07104253749242	0.177420856923662
D100G,K101E,P105S	NA	NA
D100G,N121D,Y137F	NA	NA
D100G,N124R	-0.338594052865613	0.138339147368792
D100V,A133G	NA	NA
D100V,N121S	0.465002678761776	0.128332052209689
D102G,E118D,P123Q,R141G,S158P	-0.100661454579945	0.189067972962503
D102G,I136V	1.38126145917987	0.118651852294118
D102G,L120H	-0.14326112083024	0.147573916941954
D102S,Q117M	0.663031561760205	0.113978296688436
D102V,A129D,C138R	-0.0237582566574089	0.119998079933431
D102V,I136V	1.32670540368621	0.0512586961582135
D102V,L113P,N124R	0.0289497818753488	0.121629400882486
D127G,C138S,K153Q	0.257272404592271	0.120694678925739
D127G,C138Y	0.216109166189074	0.112115880116641
D127G,E132G	0.196124980665541	0.0584834159876339
D127G,I136T	0.608297055112371	0.121538006283206
D127G,R141F	0.295036921845892	0.0492241971200761
D127G,Y144D	-0.300163975242437	0.147225607066604
D127I,A152R	-0.10299378519676	0.0704848594629999
D127N,A129P,F155V	-0.133048625182373	0.0985741825069604
D127N,K154M	0.544787431162615	0.211384863638694
D127Q,R149L	NA	NA
D127R,A156L	-0.127967923422084	0.178378046155619
D127V,K154M	-0.164273929318873	0.0697094026892794
D127V,Y134C,Q139R	0.249937735460256	0.182576321951679
D19A,E98G,Q117F,N121K,E143M	-0.0375958698058628	0.125918775008975
D19A,F77C	-0.179545851131616	0.122880822749287
D19A,M36T,M62N	-0.288164885314549	0.134360114662188
D19A,N121R,R147S	-0.116588235956477	0.0983440899633479
D19A,R104G	0.103283561646633	0.108090757805644
D19E,G34V,G47K,F77Q,N85I,L120R,R147S	-0.0783667647962965	0.112556833612415
D19E,Q117R,Y137C	-0.12868475892903	0.130875652748277
D19G,A131G	1.61933725076975	0.128701084154326
D19G,A131V,Q151R	0.18440464162487	0.205783739868859
D19G,A156V	0.787477524097159	0.197250656078781
D19G,A44G,K110R,E143G	NA	NA
D19G,A44T,H83N	0.692885805172563	0.138923395477971
D19G,C75R,P84L,N124S	0.230898493333348	0.107276983135126
D19G,C75R,P84L,N124S,F155L	0.910349316896767	0.144305657871293
D19G,D127A	0.460013848816852	0.167797814124565
D19G,D127G,R147S	0.128858056474394	0.197601502795485
D19G,D33N,N85I,L97I	0.0689098243114909	0.142107728299939
D19G,E98G,T108I,Q126P	0.0397471177463079	0.113809036487638
D19G,E98K	1.12797124502961	0.123219791513426
D19G,G47E,K48R	0.648793902807481	0.174895253901065
D19G,H20R,N85S,R104G	-0.291586257018289	0.0360451312711215
D19G,I96T,Q126H	0.837038874508552	0.193844747763524
D19G,K101E	0.646711447194563	0.109775959226032
D19G,K48R,W103R,N124F	-0.141032446196291	0.10552376359726
D19G,K74N,E122M	0.933911491755413	0.107504413024502
D19G,L114S	0.881370674108243	0.179833453554426
D19G,L38P,K146E	0.103626746187756	0.0416642404070933
D19G,L60C,M62L,P80I,P123R	0.236339593835015	0.192948848224899
D19G,M36I,K110R,P123Q	0.222662070133515	0.162200738988043
D19G,M36I,P123Q	NA	NA
D19G,M39K,N85S,R104G,I107T	0.711507895317886	0.154011490422823
D19G,M39V,V142E	0.240957588906926	0.107030621035764
D19G,P157S	0.610234006488716	0.219800524655128
D19G,P28L	0.0885637712519567	0.0934306656435888
D19G,P28L,S158P	1.536593865852	0.171330144539101
D19G,Q139R,R141G	0.0563245335366854	0.114749086626867
D19G,R104G	0.313181748351813	0.179524453264043
D19G,S95A	0.165012721942459	0.198373509156146
D19G,T35A,K59R,K146R,A152T	0.220451942318215	0.184765505683178
D19G,T35A,Y87H,I96T	0.268546581237597	0.17609064255947
D19G,T91A,R104K	1.21908089311406	0.109883348491398
D19G,V92A	0.218581834138344	0.175837580205941
D19G,W53G	0.0161651110370942	0.121160762562005
D19G,Y87H,T91S,I96T	0.0856886647688348	0.118386914528755
D19N,D33F,F58R,C75V,Q111V,N121D,E122G,Q151L	0.219744182525527	0.0861586718257109
D19N,K101R,Y144C	NA	NA
D19N,M62V,E78V	0.561576996141865	0.044321245086947
D19N,N37Y,K101R,Y144C	0.622152162739063	0.210050444169394
D19N,Q130L,A150L	0.427099088838989	0.0988048695220122
D19N,V25L,I45V	0.840857429258122	0.146468384636637
D19V,G55Q,Q117M	-0.126110960006508	0.164147822728146
D19V,K110E,Q126S	0.347252731314503	0.11239139854211
D19V,L81S,C93R	-0.0428720696725753	0.100108238209411
D19Y,G23C	0.377901692601219	0.116330270753023
D19Y,G34S,P52N,P72Q,P105D,K110R,I112T,L113P,L119H,N140S,K153G	0.201902663800673	0.260820961427077
D19Y,G34S,P52N,P72Q,P105D,L113P,N140S,K153G	-0.0687844585499313	0.164303074120691
D33A,L97S,Y137F	0.0560625385994128	0.16928235253631
D33E,G115E	-0.390846971752267	0.10947123404964
D33E,S95P,Q130R	-0.207988261517344	0.112753832935456
D33E,V142A	0.503744660269355	0.121164639009604
D33E,Y134H	NA	NA
D33F,T108R,N124R	-0.422253224397743	0.123110949667928
D33G,C93G	-0.223251808138462	0.161524126910243
D33G,D127G	0.0727710006914599	0.119715217892101
D33G,D66E,P72S,I96G,P123S	0.203244989583963	0.179545570337639
D33G,D66G,E143Q	0.725589896527285	0.188136845476152
D33G,E118L,R147G	0.0346508991079126	0.128466392871131
D33G,E143G,Q151H	-0.184746239397911	0.127754051700501
D33G,I109T	-0.04258472908096	0.118253273928207
D33G,K153E	-0.0621983839078229	0.0396153744155929
D33G,L63P,S95P,E122G,D127G	NA	NA
D33G,M39V,N124Y,A150T	0.512856033857754	0.200773899713371
D33G,M39V,W103R,N124Y,A150T,F155L	-0.0870818229842862	0.194273084500688
D33G,N121Y,A156I	-0.194987634664785	0.118117710835064
D33G,P105Q,Q151R	-0.0300557255232999	0.109539191362091
D33G,P123L	0.137345275645577	0.107961037616724
D33G,P123S,Q130R	-0.202509667557254	0.171012665551086
D33G,R104N	-0.0588129799969676	0.208016277546265
D33G,R147G	-0.026059138851812	0.201459514143322
D33G,R147G,K153E	0.147527422091722	0.144380762367482
D33G,T51N,P52L,P69S,N85Y,T135R,Y144C,F155C	-0.0792941848314692	0.192298033231739
D33H,T35A,E122D,Q130R	0.0858024551281047	0.118857794727966
D33I,I125A,V142E	NA	NA
D33I,Q126L,A133T	0.0273081529112541	0.160846496348203
D33N,C75R,S95P,E145G	NA	NA
D33N,R61P	-0.247539725812694	0.106545559461452
D33N,S158P	0.587046280681024	0.114640906204467
D33N,S95P	0.250426747984733	0.101352038581068
D33Q,R61G,T135A	-0.0295002685805983	0.110520931877175
D33S,F77H,I112M	0.0181276639524651	0.0989757624615675
D33S,R61Q,E143V	0.0782571418681614	0.116588823270366
D33V,C75G,Q111V,E145G,Q151L	0.1679864791604	0.19860892804994
D33V,L60H,N121I	-0.0730279464994229	0.121950972077384
D33V,M62T,N121T	0.407634195995636	0.142075035756308
D33V,T51A,L81Y,S95Y,C138R	NA	NA
D33W,F77P,K153Y	0.324567010919014	0.120006180550091
D33Y,C75R,W103C	-0.185878161211016	0.120484256071529
D33Y,E42G,K110R,L113V	-0.00288853504532625	0.104932979695462
D33Y,P128S	0.412506986802485	0.180840634226655
D33Y,Q151R	-0.394464440079754	0.240410959704303
D66A,Y87D,I116W,E143V,F155Y	0.194366474787117	0.130064379946077
D66C,P79L,L113P,I125T,E132G	0.159428737822716	0.112101079345965
D66E,I107P,N121S	-0.00677993712655505	0.126342775951555
D66E,I107V,E122D	0.839561756942031	0.148180603805119
D66E,K110N,E122Y,Y137P	0.272907365574247	0.133281576617627
D66E,R104G,L119T	0.473107119589486	0.12004179603464
D66E,V92M	0.183139237904615	0.1079020625478
D66F,I109G,E118V,I136V	0.125961832057261	0.134147356852853
D66G,C75Y,K76E	1.44882411922801	0.12582285352667
D66G,E98D,R104K,L120P	-0.107434335303104	0.0691113651774443
D66G,E98D,R104K,P105A,L120P,N140D	-0.087423320105492	0.249957836560583
D66G,H83L,K154R	0.185004775187278	0.225583817415091
D66G,K76E	0.554815148721562	0.289351581631645
D66G,L94P	-0.110532888389693	0.0491969055347712
D66G,L94P,I116V,Q130L	0.0564893785440661	0.106086804990051
D66G,L97S,I125T	-0.398778425833688	NA
D66G,L97S,Q139R	NA	NA
D66G,P73S,L97S,I125T	0.0752223542802749	0.157552672984528
D66G,Q111L	0.886863396060343	0.107877083891686
D66G,R104C,A152V	-0.23291159446406	0.129885107189332
D66G,R141G,Q151R	-0.0517339587347789	0.180058021274037
D66G,S158P	0.263944595124856	0.133726941832649
D66G,T135A	0.281106931081054	0.132935705519864
D66G,Y144H	-0.141827070360006	0.135297969653413
D66H,A106T	-0.0657332383703715	0.125190501508625
D66H,N85S,L119G,Q126R	0.0636354837227134	0.119688084002711
D66I,D127C,Y134C	-0.119402496475726	0.139286761358335
D66I,L81R	NA	NA
D66K,E122D	-0.143698425427813	0.0470174127215383
D66K,Q130L	-0.0547228534677602	0.185654291050172
D66L,L114D,I125T,K154E	0.286384404745615	0.129697289744283
D66L,P79R,Y87N	0.271414729624358	0.133131976439781
D66N,W103G,D127V	0.500904865697311	0.0996400486060257
D66N,Y137N	2.12671312345604	0.110781521938082
D66Q,E122Y,V142A,R147G	0.165701322201752	0.167270475836958
D66R,N121E	0.39926093177535	0.133822934833339
D66S,L120K,R147T,Q151P	-0.0694435719835381	0.13297256190128
D66V,C138Y,K146R	0.0492864445852048	0.214957701588705
D66V,W103R	-0.0984691021172483	0.129320525044746
D66W,K110S	-0.0471806074787978	0.139410873493431
D66Y,I109L,Q111C,L113Q	NA	NA
D67A,F77L	0.595136147938292	0.166079904428433
D67A,K74A,A131T	1.38600833495184	0.190696913099122
D67A,K76H,R104G,E143K	-0.0897740894790284	0.138269283078602
D67A,T108S,L114G	0.617584723900059	0.112287903680794
D67C,Q111G,D127P	0.183883508166566	0.110314549226522
D67E,I109T	NA	NA
D67E,P84L	1.03219486124428	0.0976625571016053
D67G,A129T	-0.424241832280935	0.237603210719487
D67G,F82S,V92A,Q111L	NA	NA
D67G,I112V	1.24233444735164	0.100913632916551
D67G,K153E	0.319279211568985	0.225816083474111
D67G,L113Q	NA	NA
D67G,L113Q,L119R	0.338090880904877	0.187897832810333
D67G,Y87D	0.147473488251786	0.104645110890117
D67H,I112K	-0.26870728231817	0.107631507264585
D67K,E122D	-0.0203152536294964	0.146937784583346
D67K,I109T,Q126S,A131V	0.0571107178158507	0.166453056136405
D67K,R104G	-0.407533370768229	0.109678453774504
D67L,E118D,Q126R	-0.168026190020525	0.157313496158166
D67L,E122I	-0.199068274984363	0.136691439037631
D67L,E122L	0.0293713260216805	0.149096248535325
D67N,E145V	0.0479983782422527	0.106343708939847
D67N,I107F,I112V	0.162540961288084	0.367829007708918
D67N,I112V	0.0343444456394444	0.195407410126305
D67N,K110I	0.42612390160883	0.182030048984874
D67R,F82S,P123V	0.144474112882508	0.105551574503978
D67R,N124G,Y144H	0.133583707398921	0.126981905527419
D67R,P88T,N121A	0.322147580694774	0.118246845848992
D67T,A106I	-0.107183407379008	0.0415210270927428
D67T,F82P,E118L	-0.181526840164874	0.111842031245634
D67T,I112E,L120C	0.151987647220103	0.127763444108623
D67T,I116A	0.784299993234388	0.181112141614743
D67T,P123S,Q130R	1.05784207891296	0.101364067247009
D67V,A152S	-0.166790162492888	0.107035643449602
D67V,C93R,F155S	-0.135312751163621	0.125300410769567
D67V,C93R,K153E,F155S	NA	NA
D67V,E78G,E143G	0.101329964552178	0.180468927569829
D67V,V86A,L119P,Q126R	NA	NA
E118A,Q151A	0.10427933471967	0.115901667455948
E118D,E122D	0.296676174784724	0.122697041830802
E118D,Q130R	NA	NA
E118D,V142E	NA	NA
E118D,V148A	0.981478456868711	0.179844827485863
E118F,R141V	NA	NA
E118G,D127G,Y137H	0.369072479028505	0.154762857776546
E118G,T135M	0.378493395800216	0.0957405372751536
E118K,S158P	NA	NA
E118T,V142A	0.368558806003183	0.132452479708345
E122A,K153Q	1.27085530499807	0.135873307457251
E122G,D127N	0.0201184630600058	0.0989608240456371
E122G,E132G	-0.0533530646409176	0.0655273103372643
E122G,F155L	0.477798825955181	0.193682765425033
E122G,I136V	0.423759430983092	0.122123946822366
E122G,K154E	0.0541378486680069	0.12154915473832
E122K,D127G,K153M	0.00914836769183744	0.114214498534611
E122K,N140T	-0.0296492081413438	0.209421102797153
E122K,R147L	0.370864290753719	0.146735443347422
E122L,K154T	0.265845604746204	0.117899096769777
E122L,Q126L,N140Y	0.111580391054057	0.113763170177147
E122Q,T135S	NA	NA
E122Q,Y144C	0.342114356871844	0.116831274039439
E122R,E143G	0.920113383169453	0.178426797083525
E122S,R147G	-0.161355004437014	0.116502126102674
E12A,I96T,K146I	1.78700437872025	0.197823791908128
E12A,R104H	NA	NA
E12A,W41R,R104G,S158P	-0.0451272065887795	0.10819115346093
E12D,K14R,D67E,N85Y,I109T,I125N	-0.0338425648948048	0.100959392674304
E12D,N85K	0.0645257557451171	0.109928458453754
E12D,W16L,K30I	-0.085896408763445	0.113770973872763
E12G,A26V,P32L,F58S	NA	NA
E12G,D19G,T35A,E98K	1.5419003600071	0.109059772493135
E12G,F24L	NA	NA
E12G,F24L,K146E	0.0104434906159226	0.0559464230570099
E12G,F64S,Y134L,R147A	NA	NA
E12G,I109L,L113W	-0.183908175821726	0.142420832347614
E12G,I125V,E145K	-0.0627493928739393	0.106557395479013
E12G,K101R	0.00882186536766506	0.0918679401976059
E12G,K18I,D67N,I107T,Q126P	NA	NA
E12G,K18I,D67N,K74E	0.135627478276034	0.10656117445822
E12G,K48E	0.161923301278959	0.0788502255525864
E12G,L63P,E118L,P128S	-0.154465550704457	0.184809681760033
E12G,M62T,F64S,K74E,Y134H,V142M	0.0955627329988001	0.214548694646801
E12G,N140I	0.686988297540549	0.143519980803473
E12G,N140I,K146R	2.06477450147605	0.149084308474525
E12G,N140Y	-0.0279061298506453	0.104274437033524
E12G,N37S	-0.166510505710031	0.128740091839418
E12G,P32L,S70P,R147W	0.410994586920457	0.175917334869742
E12G,P46S,D127N,A129P,F155V	0.0490114758342891	0.250754025964952
E12G,P72L,I109L,D127G	-0.0429107250130274	0.107404102943601
E12G,P80I,Y87F,L113T	0.92687979977546	0.113923667914692
E12G,P80V	-0.328148302198233	0.214835613560847
E12G,Q151A	1.13477000893601	0.206663812259574
E12G,T108L,Q126S	0.119753419220086	0.105610680394897
E12G,V27A,K49E	0.123704679071584	0.149354956490115
E12G,V27I,C75R,Q130H	0.841761252898119	0.164023463298738
E12K,R141S,S158P	0.233951194848148	0.197277536980693
E12K,T35M,I112R,E132F	-0.457837388167336	0.159910246989061
E12P,M36A,L57E,N121K,Q126K,V142A	0.118148138650065	0.130208859582321
E12P,P123L,Q130H,A131L	0.089505749966727	0.157954146990274
E12Q,D33I	NA	NA
E12Q,L97S	NA	NA
E12Q,P52Q,S95F	-0.142892270894353	0.115276132645304
E12R,F58Q,K101E,I107F	0.0296884275268364	0.073672383697558
E12S,A106L,N121S	-0.19929897860134	0.143359787443625
E12S,R104H	0.173452606738838	0.1195765998104
E12V,A26V,M39T,V142A,E145K	0.0059773903108971	0.0906085565937183
E12V,D19G,K59R,K146R,A152T	0.0461240551523981	0.198986388251704
E12V,H20L,M39T,F77S,N124I,A150V,K154M	-0.161563342673299	0.186647356207361
E12V,I112A,K154R	0.148824238390802	0.136507809528264
E12V,K14I,N37D,K74I,Y87H	-0.204206309970331	0.135368752602764
E12V,L94Q	-0.0561892679460448	0.118942814912019
E12V,M36V	NA	NA
E12V,M36V,L57S	0.0206159166935225	0.119012117864391
E12V,M62I,P128T	0.0534836872367711	0.102821701796618
E12V,V142A	0.116816342092876	0.213456098428565
E12W,T29P,K48R,K59N,L81T,I96T	-0.26327126940865	0.0461113442445041
E132F,C138S,K153R	0.142062569748952	0.104627682480614
E132G,I136T	NA	NA
E132Q,C138Y	0.20200403453889	0.0868507410569067
E132V,C138Y	NA	NA
E132V,Y144C	0.0974183522553114	0.117041909257716
E143G,A152G	0.110110516295543	0.144082376251144
E143G,K153E	0.907277929149194	0.20957301523551
E143G,Q151V	-0.357500533218278	0.125581047295211
E143G,V148G	0.420581954562754	0.149971680737336
E145G,R147N	2.09908982355007	0.116547608250587
E42A,C75R	-0.0842753118465818	0.106668169587437
E42A,I136T,E145G	0.207264600919764	0.157153056194285
E42D,L120S,V142Y	-0.258234109722253	0.122437024244748
E42G,A106V	0.0481302267598874	0.121337864974107
E42G,A44V,K59N,N124K,E143H	-0.069339916465491	0.109458258031677
E42G,C75R,E98G,Q126H,N140S	-0.174076621705554	0.130582514528417
E42G,D102Y	0.046840532631221	0.10462001972485
E42G,D66P,N121M	0.847913079132856	0.107789214690468
E42G,D67Y,K153R	0.250280768006079	0.120148699822434
E42G,E145V,F155I	0.127395224158929	0.12228602811071
E42G,E78G,E99G	0.143655004625311	0.106822169395854
E42G,E78G,I107N,N124S	0.0629251432668533	0.105474231927061
E42G,E98G,L119R	0.141599866021531	0.17441539680462
E42G,I116V	1.45516105242031	0.42224403858955
E42G,K110R,T135A	0.284202866163351	0.138190112082794
E42G,K49E,F64S,I109V,T135M	-0.281811661926175	0.114333435139302
E42G,K49R,S71L,P72L,C138G	0.202612894068929	0.214736704752631
E42G,L113V	NA	NA
E42G,L114A	0.75977204454253	0.106081436953019
E42G,L114S,N124S,E143V	0.376129504906681	0.133139747892513
E42G,L114S,N124S,Q126R,E143V	-0.0282500539818233	0.219741430628729
E42G,P84Q	-0.405425341393957	0.115655507409498
E42G,P84Q,E122G	-0.131461333457356	0.148871138722082
E42G,R61W,L63F,E78D	0.18429572853227	0.110995631014346
E42G,W103E	0.174965788173524	0.116039381066808
E42G,W53R,P88S	0.180393268790732	0.104655986193325
E42G,Y144H	-0.0172317867193419	0.156882199722167
E42G,Y87F,E99G	1.51760074044816	0.204595708641233
E42H,L81H,I136T	0.301206132209936	0.0986172225367589
E42K,I45M,L81Y	-0.106312572022885	0.102662777287174
E42K,L113H	-0.0805375546261634	0.129414055187391
E42Q,I136M,Q139K,R141S	0.652998526631586	0.134169231590598
E42Q,I45F,E122V	0.171428072223231	0.118431866361371
E42S,K74R,I107A,Q130T,R149G	0.373225384812563	0.250634467682032
E42V,E54G	0.498064764708442	0.086561616119109
E42V,L97F,P105S	-0.169196202386831	0.0598968827598521
E42V,S95A	-0.15686199489273	0.0949615082663314
E42W,C75E,N124V	-0.220310374214765	0.156225730026679
E54A,K110A,T135V	0.227639400056211	0.121160843985448
E54A,T108P,A156V	-0.15970566822684	0.123206532711132
E54D,F58Y,C93R,E98G	0.30197493016285	0.243948420688734
E54D,F77S	-0.0740097484635169	0.162182817679722
E54G,C75R	0.170868656374696	0.111152835732021
E54G,C75Y,A129V,E145I	-0.212435691795892	0.099305708037898
E54G,C93S	-0.13971854788603	0.114803750898203
E54G,D66I,S89P,A152K	-0.108456544192059	0.173742844152957
E54G,D67I,P123S	-0.378096263038119	0.131642567536017
E54G,E145K	-0.0147064810368547	0.118050241360977
E54G,E78G,N85D,S95P	0.440737986455462	0.202590645794448
E54G,F64L,Q151R	0.0230642822018792	0.0543189958858426
E54G,I112R	0.143004866108396	0.110716909749524
E54G,K110N,Q126K	0.496006490577445	0.165080185995466
E54G,K65R	0.625466305382368	0.115501203361595
E54G,K74E,P79L,N85Y,Q126K,E145K	0.466599089461947	0.169015892569031
E54G,K76D,K101R	0.367402728530492	0.203359685263833
E54G,K76N,T91A,L94Q,Y134N,E143V	-0.371604714283244	0.271805233095838
E54G,K76R	0.655183079021716	0.210943010456588
E54G,L63V,D67A,P73S,E99G,I116V,Y137C	-0.0244377070640286	0.141173407386746
E54G,N140S	0.0900767000658771	0.119271368634263
E54G,P79L,E145K	-0.0493818900736231	0.0534553678486917
E54G,Q151R	0.419098826784604	0.20219280964354
E54G,R141Y	-0.196299709930405	0.196676149817901
E54G,T91A,Y134N	NA	NA
E54G,V86A,I116V	-0.282066707801011	0.0419293453928467
E54K,E122G	0.201644898715998	0.103971785262285
E54K,F64S,F82I,I125T,Y144C	0.179857212457738	0.228186485131562
E54K,F82I,I125T	-0.024552028036006	0.0544842064151144
E54K,L63P,D67A,Q126L	NA	NA
E54K,Q126S	0.290692480703879	0.138113923749305
E54P,F82S,Y137C	-0.0134762600846242	0.130599466036751
E54V,G115E,R141G	NA	NA
E54V,I116V,Y134N	0.247422775205693	0.153516003340263
E54V,K74S	1.28776657954334	0.171792898377958
E54V,L60P,P69R,Q130L,A131V	-0.198438138653115	0.110180815241804
E54V,M62G,I109M,Y144C	-0.391373287457695	0.198535284759095
E54V,Q126R	0.65007715404031	0.197794336512547
E78G,A106T	1.5935072294108	0.0923870812384239
E78G,C138Y	0.0364208108691551	0.139808385759787
E78G,E132G	NA	NA
E78G,I116M,Q139R	NA	NA
E78G,I96V,P123V,Q130H	-0.0349626879581797	0.182939013237102
E78G,K146R,V148D	0.0193949678852473	0.310561646779263
E78G,Q111K,Y134P	0.20523889329261	0.0932554545562065
E78G,V148A	0.451305385805793	0.155423896791709
E78K,H83Y,D127E	-0.00812413413028313	0.0579810661488912
E78K,H83Y,D127G,C138Y	NA	NA
E78K,R147W	-0.371756879337311	0.195167906795819
E78R,I107L	1.11361287398668	0.119676475492935
E78R,L113P,K154R	0.336455994456925	0.102029556503568
E78R,Q130R,V148F	-0.361871465706705	0.192195258548469
E78T,K110A,Q126S	0.0768778721863718	0.13740470014409
E78V,E143G	1.45786755951349	0.181968381520845
E78V,H83Q,L119C	NA	NA
E78V,L113Q,R141K	-0.204803542475706	0.0565862425458747
E78V,Y144S,P157S	0.515165889486012	0.183076239025043
E78W,N121L	-0.0939015073151738	0.192917468500615
E98A,Q126R,Q130R,K153M	3.45348571774325	0.174581594993097
E98D,R141G	-0.53383897261064	0.178756809268253
E98G,F155L	1.84843046572111	0.260650189420626
E98G,N140I	0.10134645204867	0.111321751262681
E98G,Q126F,Y137F,V142T	1.71681096740875	0.139365186027032
E98G,T108A,L119P	-0.22176911484303	0.114998366646855
E98G,T108A,L119P,N121D	0.85442781377711	0.133779905586161
E98K,Q111M	2.4082207845682	0.207382946341847
E98K,Q111M,I112V	2.57861892645341	0.191189135675326
E98K,Q117N	0.961400412443005	0.104594320211499
E98V,I107L,R147V	NA	NA
E99G,K146R	1.09529125410687	0.177921861712739
E99G,K153Q	0.092001321530518	0.222998784269798
E99G,L119F	2.22214995748759	0.122009264057679
E99G,L119F,F155L	1.17173844967667	0.218737608692115
E99G,N140D	0.742931707531839	0.294413424895679
E99G,Q130P,V148A	-0.106101736274869	0.0559451623049953
E99K,I109R,V142T	-0.122946856097637	0.12839467203858
E99K,P128Q	-0.0948097151257699	0.209652059931519
E99K,Q130H	0.349822498114032	0.104405947078488
E99Q,C138R,N140D	0.648235437443636	NA
E99V,N121I	0.185043214823242	0.12938498926085
F155L,P157H	NA	NA
F22C,N31D,N40Y,K48R,L57S,S95P,N124S,Q139R,A150V	-0.482300854243266	NA
F22C,N40Y,N124S	0.0589216925598852	0.113677290689975
F22E,P52K,Q126R	-0.246410702222295	0.144225968295488
F22H,T51S	-0.426470542817072	0.162468791344208
F22I,G47R,Y68S,K110E,E132L	0.116933842793978	0.164237422905179
F22I,K30R,N40T,R61P	-0.236178828746135	0.127343488275761
F22I,Q126R,Y137C,Q139H	1.57354430121663	0.182241084941356
F22L,C93S,Y137C	-0.187484832426483	0.0726132553471808
F22L,D102G,I109L,A131L	0.341415791998502	0.202050894902701
F22L,D33G,M39V,K101E,P105L,N124Y,A150T	0.268989109465503	0.0988485614307664
F22L,E143G	0.285836490067506	0.060024277684211
F22L,E42K,K101E,A150T	0.195267715201919	0.121686087750492
F22L,E99G	0.435394172813001	0.0315419328432372
F22L,E99K,Q111H,L119V	0.51957002045421	0.199522906714489
F22L,F58L,S95K,A131Y	-0.12889739683119	0.0744535976007425
F22L,F77L,K101M	-0.0701024192605917	0.235543531273075
F22L,G23M,T35M,Y87N	NA	NA
F22L,G56D,K74R,K76R,I107V,I116T,A152D	0.370152530309875	0.161055151917064
F22L,G90R,P157S	0.131078381412022	0.103324747054967
F22L,I45T,G56S,L57S,E143G	0.0805403042826113	0.115731188152026
F22L,I45T,I109V,G115V,E145V	0.160975272519166	0.15858310180784
F22L,K101M,Q126R,Q139H	0.494627924569944	0.160819620646017
F22L,K110R,Y144C	0.461823138711636	0.138836617116142
F22L,K146E	1.08204732475118	0.20760937521133
F22L,K30N	0.040139087956478	0.109942700313872
F22L,K48R,N85Y,L97V	0.172430963482014	0.173139107390492
F22L,K59R,E122L	1.04847586260629	0.140928199501428
F22L,K65R,R104G	0.622211530260957	0.111386732616559
F22L,K74R,K76R,F82S,I107V	-0.115343866737865	0.237795099214446
F22L,K74R,K76R,I107V	0.457957518378525	0.10177471547241
F22L,K74R,K76R,N85S,I107V	-0.103467038881063	0.198868356926891
F22L,L119I,E122V,A156E	0.120160010687436	0.0714690857246524
F22L,L94Q	-0.0364197926620334	0.111496448376334
F22L,N31I,Q126T,K153R,A156K	0.224164928655382	0.134881942427242
F22L,N31S,T91S	-0.0994392672980209	0.0980174314350099
F22L,N37S,H83R,K110E	0.154536030120205	0.065788005098402
F22L,N40D,E99A,K110R,P123T	-0.0699183571407953	0.102136071554536
F22L,N40D,K76E,F155S	NA	NA
F22L,N85S	NA	NA
F22L,P32L,N40Y	0.593590855165872	0.111801313880745
F22L,Q126R,C138N,A152S	0.0666407255501188	0.141644894657302
F22L,T51I,L94Q	-0.222525382697149	0.193191632005351
F22L,V25A,L94Q	0.531344103204487	0.126672193562275
F22L,V92A,K101M,D102G	0.668532045263832	0.143545284283528
F22L,Y87N,S95P,K110L	-0.124466816862584	0.122093615036359
F22M,N121L,A131V	-0.353713373650706	0.124277094171653
F22N,L113E,E122G	0.00935800980836238	0.151885700147527
F22R,N31I,N40D,L60K,P73T,L94I,A106L,I125G,R141N,A156V	-0.103602020264752	0.0805056337636634
F22S,A131T	0.055083895757171	0.115759928005454
F22S,D33Y,N124S,T135W	0.655823049127985	0.105518974835448
F22S,E54G	1.01078704878197	0.0985656240615752
F22S,E54G,F58C,A133G	0.40151854733372	0.373305598393585
F22S,E78R,N124S,I136S	-0.446087579387235	0.181384984000565
F22S,F24L,P72L,A156V	-0.129847870076905	0.107537208302504
F22S,F64S,L97S,P105L,Q117R,K146E,A156P	-0.0423683573240171	0.12035027650729
F22S,I45F,K65E,D66E,N85S,Y87H,R104G,E118D	0.0760677769337678	0.174891610415308
F22S,I45F,K65E,D66E,Y87H,T91R,E118D	0.239822916382002	0.172938785916692
F22S,I45F,K65E,D66E,Y87H,T91R,L94P,E118D	0.223994088897378	0.170053570038476
F22S,I45T,R61P,P72Q	-0.193582461813621	0.116862520750316
F22S,K74D	-0.309707423578233	0.151593806283
F22S,K76R	0.0309092222391411	0.11981480320905
F22S,L119P	0.0647201294221324	0.0925175341876081
F22S,L57M,F64S	0.121074606998659	0.109626064290581
F22S,M36T	-0.111690225876385	0.199089445484117
F22S,M39T,R61W,Q126H,V142A,E145K	0.35322938728094	0.16844993492442
F22S,P105C,P123S	0.606560333791414	0.158875413470836
F22S,P123S	0.246660288126531	0.119856522856341
F22S,P157L	NA	NA
F22S,P32H,K48E,R61L,S71P,L94K,P105V,L114R,Y137N	0.433972752539659	0.176551651412854
F22S,P32H,K48E,R61M,S71P,L94K,L114R,Y137N	0.0775361019052863	0.0796669443451363
F22S,T135P	0.0131404385371757	0.115678592059674
F22S,T35M,K49E,Q126R	0.15931257311646	0.0997790263349184
F22S,V25A,V86A,K101R	0.109775766067143	0.120227545148363
F22S,Y137D	NA	NA
F22S,Y68C,E143G	-0.114801594895682	0.0410423024803149
F22T,F82W	0.24293382467479	0.165615646310136
F22T,L113H,K153F	-0.0504387264243582	0.0838317039226934
F22V,D33G,K153N	-0.0383256560240073	0.113675820016162
F22V,K74I	0.160239782881419	0.0759609679101592
F22V,N121K	0.800721629252604	0.110892454266755
F22Y,E42V,F77S,L97F,P105S	0.401817019664691	0.119157021436698
F22Y,G23C,Y87C,R141G	0.191437549399926	0.108646305465316
F22Y,G55A,L120Q,N121D	0.310147101112419	0.216994939620031
F22Y,K101E,R141G	1.36225118959304	0.139378017908528
F22Y,L38P,K76T	0.0162009847430804	0.129007963293329
F22Y,T51I	0.187412648003838	0.0927793131072644
F24A,K65N,P72A,Q111L,A129S,R147E	0.374756655220334	0.213424301186934
F24A,N31K,E42A,G55M,K76A	-0.263916872991087	0.115537137129311
F24C,C43R,P84Q,N85Y,I116K	-0.226667096312821	0.179655389603912
F24I,C75R	-0.0361907036406355	0.0443320112372127
F24I,C93R,K110E	-0.176048756833992	0.117871273678453
F24I,F64S,V148I,R149Q	-0.0917392489515658	0.0891370665325927
F24I,I107F	0.0328083009170748	0.191214962740426
F24I,I107F,I136T	1.32852207360126	0.154253926181789
F24I,I45F,W53R,P69S,P80S,Y87D,A129V	0.19946088253106	0.14194694581536
F24I,K110E	0.251432745061501	0.173309482680963
F24I,K74R	0.458207074907551	0.108018109644436
F24I,P80L,V92A	0.120224850404141	0.113913604676706
F24I,S71P,E118D,N124S,Q126R	0.465909387311662	0.103203707778645
F24I,V148A	NA	NA
F24I,Y87D	0.170788052517218	0.119109506362094
F24I,Y87D,L114S	0.289351463659515	0.111507401110637
F24K,K59N	-0.383247265847622	0.128679505192339
F24L,A26S,K48E,K65N,C93S	0.477668839099639	0.128644795581426
F24L,D33Y,W41C,S95P,F155L	0.0781923415575535	0.102671603603753
F24L,D66T,R147Q	0.142358112529199	0.160528154745773
F24L,F64L	1.42476045748056	0.201885277451331
F24L,F64S,N121Y,K154Q	0.479307219055844	0.107672178212909
F24L,I45T,K74E	0.269982199462878	0.16811546998985
F24L,I45T,K74E,N121Y	0.608969500868228	0.134438003628567
F24L,K101R	0.349389837006188	0.125651261624768
F24L,K101R,N121H,A133V	0.58757332115393	0.196511826893234
F24L,K154E	0.0671807502364501	0.0595288724265062
F24L,K48E,I136V	0.53240695875601	0.197546999602496
F24L,K65E,N140D	0.287439302859301	0.107727417847502
F24L,K65R,Y68C,I96T	-0.132191290830099	0.0926080435216425
F24L,K74E	0.390252355499052	0.174655513887165
F24L,N124S	-0.0062341972114544	0.25439280352627
F24L,N37S,M39V,K49E,H83R,C93R,I96V,I107V,I125V,R149G	0.0232430394918736	0.0460799867075174
F24L,N37S,M39V,K49E,H83R,C93R,I96V,I107V,I125V,T135S,R149G	0.317024759260921	0.168904873311824
F24L,N37S,M62V,R104W	0.0176539924972769	0.0819984514059138
F24L,N37W,E118N	0.150954719664124	0.102546480756845
F24L,N40S,E118G	0.0119677545769335	0.112603883106825
F24L,Q139L	0.0934437317544261	0.102520683258382
F24L,R104G,K146E	-0.0453469938298389	0.113424463121244
F24L,R104G,Y137H,C138R,K146E	NA	NA
F24L,R61Q,K146R,K153R	0.829062613804296	0.18633313811331
F24L,T135M	0.372632474457823	0.176864621758836
F24L,T35P,Y87C,L113C	0.331335489852778	0.100669470932672
F24L,T51S,I109V,I116M	0.0283739297258905	0.117175356832993
F24L,T51S,I109V,I116M,K146E	0.692379235424688	0.155510978174405
F24L,V27A	0.114906768570494	0.0357317021700754
F24L,W103C,Q139H	0.259345120919928	0.175184209219884
F24L,W103R	NA	NA
F24L,Y68N,R104K	0.718730374255129	0.141963821498532
F24N,N40Y,L120M	-0.0614017634832246	0.14990045507358
F24S,A106S,E118K,V148A	-0.227193623781282	0.170181399431848
F24S,A26G,E99G,Q126H	-0.396409662852648	0.180187368027979
F24S,A26S,K59N,F64L,F82L,E122M,T135P	0.048446390461894	0.106854991196502
F24S,D127G,A131G	NA	NA
F24S,D33G,E54L,L63P,K74S,E122T,Y137R	0.13713415735293	0.133620173717608
F24S,E78T,R141V	-0.181918231842064	0.133184816068852
F24S,F58S,L81P	-0.207336733794961	0.250583488083446
F24S,G56R,Y87C	0.313596376054173	0.111879093105091
F24S,I112N	0.381498075680192	0.177259701060072
F24S,I125T,K146R	0.0409424725603347	0.0885504917854987
F24S,K146E	-0.158586147011743	0.123671067884269
F24S,K48R,C75Q,H83L,Y87D,I112R,V148Y	-0.50983974368798	0.153086554371731
F24S,K49R,Y134F	NA	NA
F24S,K59I,L94R	-0.0417013471376943	0.120502273623264
F24S,L114F,G115R	-0.091888035452782	0.101041425791172
F24S,L63P,V142L	0.179397694663688	0.119244338893434
F24S,L97F	NA	NA
F24S,N40Y,P84S	-0.0112910061276938	0.0787459388046592
F24S,P79D	0.116165916836908	0.105151322736936
F24S,T35A	0.156939819409152	0.161618626983201
F24S,T35A,N40D,E118V	0.206154604825317	0.191444517457285
F24Y,E54G,N121S,E132G,A152W	0.433923319596005	0.14166697659521
F24Y,E54G,N124D,E132G	-0.0885551268365667	0.132010607404687
F24Y,G34A,L119G	0.132767884595596	0.149338434410045
F24Y,H83M,N85H,N121A	0.14409100360136	0.104647681052393
F24Y,K48E,E54G,N124D,E132G	0.960912845799215	0.208503850572918
F24Y,K59R,I112T,N124S,Y134N	-0.131860903521422	0.150174887868291
F24Y,T35P,G55P,D66S,D102G,Q111H,L120V,Y134A	0.0835579041874765	0.170492166341594
F58C,K59N	0.375157394618604	0.187024102442807
F58I,Y87C	0.2213364442792	0.108938087961548
F58L,A131V	NA	NA
F58L,A131Y	-0.304548081989879	0.242545548214922
F58L,A133T	0.0907283956016858	0.157077556679674
F58L,A156V	NA	NA
F58L,E145G,K153M	NA	NA
F58L,E78G,Y137C	0.394538914005154	0.261337225648588
F58L,E99G,I109T	NA	NA
F58L,F155S	NA	NA
F58L,F64Y	0.336099673017819	0.140529753533654
F58L,F77L,V86A,K101E,S158P	NA	NA
F58L,F82R	-0.159972902621976	0.13832426413346
F58L,I116K,D127M	NA	NA
F58L,K59R,F77L,Q151R	0.125432272481329	0.136616135820683
F58L,K76A	-0.252116019275064	0.172869544077591
F58L,K76R,V86A,S158P	1.00346059505352	0.158879990723943
F58L,L63P,N124I	-0.129984403842332	0.101130293763367
F58L,M62V,D67T,K110I,I116A	0.197119020128	0.16616163176794
F58L,M62V,K110I	-0.145733687482836	0.115882974594268
F58L,P72R,I109T,F155S	0.276192676957262	0.19905695239366
F58L,R147S	NA	NA
F58L,S70P,K146R	1.70705646591368	0.155395312349868
F58L,V86A	0.43283207885026	0.130260462261121
F58L,V92M	0.689216793199099	0.203500878486167
F58L,Y87F,L114F,A131V	1.94619375309752	0.208694342049946
F58P,P105L	0.104111920032387	0.256740309613438
F58R,I96T,N121S,P123I	NA	NA
F58S,A133K	NA	NA
F58S,F64L,Q126R	-0.170274572227264	0.1420025296461
F58S,K59E	-0.265231130614174	0.110150424636732
F58S,K65E,S158L	-0.0562430940521831	0.107204675108685
F58S,K74E,E118S,A152V	0.034074330710184	0.104510938938919
F58S,L63H,C75R	-0.12853265775541	0.117890799630638
F58S,M62R,C75S	NA	NA
F58S,M62V,Q126L,A133T,T135S	0.193396510125832	0.189044688184397
F58S,N121P	0.37240182857946	0.13184687004535
F58S,P80A,P88L,S95P	-0.0922464344388941	0.127432730969
F58S,S95T,A133G	NA	NA
F58S,Y87C,P105S	0.189543963893565	0.0998124962293913
F58V,E99V	0.341127820577059	0.118866643929491
F58V,K101R,K146N	0.0617966480701536	0.195682040041102
F58V,K74E,L119H,Y134C	0.0923354244832334	0.170553610131999
F58V,L113P,V142A	NA	NA
F58V,L81C	-0.0721215597373373	0.118792103512016
F58V,N121Q	0.566328605151828	0.173259486803304
F58V,N85V	-0.764339200476372	0.211817723247167
F58V,V86M	-0.289113089094511	0.20740291943344
F58Y,E118G	0.90413207856546	0.176075067451027
F58Y,E143D	0.725187026091983	0.111072448377194
F58Y,E98G	1.30764467174553	0.121820906186715
F64D,I125P	1.12551838173593	0.101331400659351
F64I,E118G,T135M	0.279757224016534	0.186854648904942
F64I,Y134S	0.0596932724126335	0.1099784336921
F64K,P88L	-0.174406198105039	0.11244367489246
F64L,C75R,P79Q,N85S,S89P,E143G,Q151R	-0.0616729399541881	0.20335649070127
F64L,D67V,K110E,N124D,K146R,F155Y	0.0944867102878012	0.185584421598033
F64L,E122D	0.294240697190646	0.0621135029885266
F64L,E143D	0.870524364297369	0.16857364372126
F64L,E99G	0.894528859796727	0.110285379907659
F64L,I107N,A150G	-0.0641630427552712	0.124745260816579
F64L,K101R	NA	NA
F64L,K76R,L97S,R141K,K153E	0.240253800066669	0.118662351364184
F64L,L114S,N124S,E143V	0.840215094581802	0.184950982272439
F64L,S70P,C75Y,F82Y	0.370002957126263	0.227479879540945
F64L,Y144S,A152C	0.0253763958221972	0.123182159388761
F64P,L114N	0.0668810763318077	0.180673186513352
F64S,C93S	0.709996764266505	0.214194579926088
F64S,D102V	0.318454179251746	0.117322691017848
F64S,F77D,I125W	0.203581011455838	0.196303463550894
F64S,F82L	1.92523755466705	0.252020728838982
F64S,I109L,Y134C,V142M	0.180502115606914	0.138514755710897
F64S,I109V,T135M	NA	NA
F64S,I116M	NA	NA
F64S,L119R	-0.0191406812739056	0.240668332195728
F64S,N124D	0.0709395404617869	0.106823326480385
F64S,P72A,F82I,C93S,R104K	0.376468030160668	0.219768126247248
F64S,P84L,G90R,T108A,Y144H	-0.0205627720783421	0.113214085052253
F64S,Q130R,N140S,V142A	NA	NA
F64S,Q151H	NA	NA
F64S,T108A,L120P	-0.00839730957638305	0.169917894485663
F64S,T108A,Q151H	0.0100961612315189	0.108287345785742
F64S,V142N,V148A	-0.419678506908767	0.124820408793137
F64S,Y134H	NA	NA
F64S,Y137H	0.209401310494481	0.0951984410401819
F64S,Y144C	-0.0460313041400792	0.124772322902951
F64V,S89P	-0.074801507848108	0.108320373740431
F64Y,A106V	0.105382658547501	0.085154771570252
F64Y,G115R	0.938955924504001	0.16734422465856
F64Y,I112V	0.848977483066065	0.110862732502157
F64Y,K146R	0.470449581117922	0.133439864563906
F64Y,R104S	0.0776437756469089	0.109019699216647
F64Y,Y137C,A152E	0.182201321570844	0.10202647340318
F64Y,Y144C	0.0470457517933405	0.116023758802505
F77A,Q126C	-0.284110843131052	0.218305128233881
F77C,L119R	-0.227018903637488	0.123836038699187
F77E,E118V	0.296599777368694	0.143187021613518
F77E,Y134I	0.324950313810675	0.107839905784135
F77H,L114W	0.0960163864133696	0.132267352412472
F77I,Q111T,G115V,L120R,T135R	0.00523536225241599	0.042247500429277
F77I,R141S,K146R	-0.159914039654898	0.0633390892285571
F77I,T91A	0.220432410681509	0.117408836328758
F77K,P80L,Y144T	0.00646104240256145	0.120198711313227
F77K,T108V,P123V	0.0744720124468767	0.344474874508236
F77L,C138Y	0.292967650249536	0.162772767142964
F77L,E98G,Y134C	0.12271303830012	0.198839909113857
F77L,I109L	0.912391137434247	0.227080200451609
F77L,K101E,R104G	0.131909165236343	0.124840725213175
F77L,K101E,T135M	0.741134485485847	0.206419358655756
F77L,K101R	0.486161026047895	0.107390552985148
F77L,K110I	0.372190706418074	0.11573242954514
F77L,K153R	0.337111048866937	0.165008949660641
F77L,R104G,N121T	0.128865053677644	0.112833988679092
F77L,S89P,V92A	NA	NA
F77L,S95T,N140D	0.00229990142301091	0.190813195251024
F77L,V142T,K154E	0.198726861935541	0.171645507598718
F77L,Y137E	0.0684286456281611	0.113211995784514
F77L,Y87C,A131V,Q151R	0.551627132976569	0.196625283331723
F77P,N85Y,L119T	0.379755804557364	0.11160038896848
F77R,N121A	-0.028387724175117	0.119399567365853
F77S,E78D,S95M,Q130L,Y134C	0.0923688083492778	0.115945691238254
F77S,E78G,P84T	1.38434793459994	0.185970218378461
F77S,E98A	0.457147652575459	0.128306500029212
F77S,E99G	NA	NA
F77S,I109S	NA	NA
F77S,K153R	0.133455514734086	0.182649022832118
F77S,L113W	-0.236707391937675	0.121105103966022
F77S,L114R	-0.0692012636658017	0.148109087385193
F77S,P84T	-0.440400775200072	0.122192246901356
F77S,T91A,I96V	-0.0505258056133393	0.111160710420931
F77S,V148A	1.0333391492647	0.15346004103598
F77T,P123G,A133P,R141G	0.121760195302061	0.0465286974841134
F77T,P123G,A133P,R141G,R147S	NA	NA
F77T,Q111M,Q117R	-0.56193090315107	0.170206554138926
F77T,S95Q,E132G	NA	NA
F77Y,Y87D,P88H,N124K,E143I	-0.0190294551295179	0.120343113628046
F82A,I109C,C138Y	0.127942782002602	0.106332842351476
F82A,W103R,I116V,L119G,N121D	NA	NA
F82E,P88Q	-0.00342403996138473	0.100648519681117
F82I,L119N,D127V,I136L	0.267136613038625	0.11405336947472
F82I,T108L	0.503116508180345	0.172057758777994
F82K,L94M,K101R,I109R,Y144S	-0.282359718402614	0.114442118900607
F82K,R104G	-0.0431242704908869	0.114723080691277
F82L,A106P,I109V,E145V	NA	NA
F82L,E118G,T135M	-0.040372061207048	0.19849718370003
F82L,E122G,A133T,I136V	-0.0264921323389803	0.114879642031627
F82L,E132G	0.439119860836078	0.159619662744457
F82L,E145V	-0.00531454450932728	0.212837696695172
F82L,I112Q	0.0908466251644964	0.123616755786182
F82L,I112Q,L119P,I125T	-0.0900853068208212	0.200946777011443
F82L,I125V	-0.253414719750959	0.135084463160951
F82L,I96V,V148D	NA	NA
F82L,K101E	0.280114599933044	0.121116559785391
F82L,L97I,K110R,I116T	0.489515125984847	0.18359070186825
F82L,P157S	-0.165082543187486	0.0937960179716602
F82L,Q111H,N121V,V142G	1.0136765897978	0.147229275043542
F82L,Q117F,I125T	0.406393996558365	0.115438625801623
F82L,Q130K	-0.0754640671692157	0.109519536866669
F82L,S95T	-0.117585959685665	0.0670255478382411
F82L,T108A	NA	NA
F82L,T135S	0.00599205952853247	0.15120414548432
F82L,W103R,I112L,I116V,L119G	2.40248818196724	0.144982094320854
F82L,Y134C,V148D	0.749985049316901	0.211688720608443
F82M,L97W,E98G	0.289710638429357	0.123783458217781
F82M,S95P,N124V	NA	NA
F82M,T91A,I96V,I109P,G115A	0.118748515042501	0.120290711285624
F82N,N121T	0.015765736515814	0.152174715514735
F82N,V142M	NA	NA
F82P,E118S	0.0103360424830369	0.123179461407409
F82P,N124Q	-0.0481817114125659	0.106822949573014
F82P,T108V	0.844255214267086	0.117990630636923
F82R,C93S	0.254189595397558	0.155610825734404
F82R,E122D	-0.424594007924573	0.326232730339832
F82S,E118F	-0.25606539033631	0.145106750586064
F82S,E132G	-0.146786319046058	0.113068897685869
F82S,L97V	-0.423257954464417	0.291559880693634
F82S,N124S	-0.133839967151171	0.215263511703443
F82S,P84L,K110R	1.6214989793078	0.227447620999903
F82S,Q111L	0.157670517521193	0.113732922876809
F82S,Q117R	-0.11081543671921	0.104738707513918
F82S,Q126K	0.109356733000924	0.0648612271985208
F82T,E98G,Q126R	0.074797909636796	0.120175928684362
F82T,R141G	NA	NA
F82V,K154R	0.130881834928249	0.0512663654909942
F82Y,A106V,I107T	0.749877571501853	0.142245563271772
F82Y,I109P,P123V	0.467485957313002	0.101047366913201
F82Y,T91N,E118S,R147M	0.0569517560018922	0.186226371575731
G115E,R141G	-0.328462104224691	0.241018852822931
G115T,C138R	NA	NA
G115T,R141G	0.389390788780931	0.107648956507758
G115V,L120R,T135R	1.2824288389331	0.167613377836865
G115Y,D127A	0.029850968523196	0.127085917153803
G23A,E122G	-0.141008168784535	0.127826655359515
G23A,Q139H	0.673227492248468	0.11550731160402
G23C,E99D	0.324653336698176	0.116245906291196
G23C,I116L,N140D,E145V,K146R,F155I	1.59788338861364	0.196887497968179
G23C,K49E,I107F,L114F,E132G	0.099343436435691	0.139175067224216
G23C,K59R,I96V	0.735097174348509	0.105923176840365
G23C,Q151L	0.0339581953823559	0.116553724818907
G23D,D127G,Y134H	0.267578320745851	0.180411733503717
G23E,F77K	-0.167003995735644	0.110537930338912
G23H,F77K,L119M	-0.130889021107138	0.129544508982206
G23K,D33S,F58A,P79L,S95N,D102Y,K110P,Y144A	-0.0890819813331398	0.032479198021942
G23K,V148L	0.265352032909112	0.124272332880563
G23K,W103H,I109T	-0.0844424489919762	0.159359826661183
G23R,K49E	1.14575549570688	0.112985226194004
G23R,K76R	0.352856900081259	0.217126165984488
G23R,L57M,F77L,N85Y,L113P	0.0696379334254657	0.162187048670096
G23R,P32R,N40D,L57Q,E78K,Q111D,G115R,L120M,V142E	0.0204426722389265	0.216531943511326
G23S,C75Q,I116V	0.120958265968718	0.130178697027651
G23S,D67G	0.559075700086367	0.106537371408451
G23S,K110E	0.0194894182220981	0.0829766908522931
G23S,L38P,M62V,V86A,P88L,P157L	0.500694424944061	0.204371320664667
G23S,L94P,P128A	0.0941209165085562	0.182060574886503
G23S,M36V,W53R,K74R	0.0170522804301301	0.120186052257618
G23S,M36V,W53R,K74R,I125T	1.02743349479052	0.150145561338671
G23S,Q111L	0.148391439492887	0.14670740640613
G23S,R141G	-0.171831646830837	0.141620065605953
G23S,S95T,R141G	0.194372996123209	0.177251253401502
G23S,Y68D	-0.0901268716738801	0.102921543688497
G23V,D102A	-0.0427557193592597	0.121219797407214
G23W,C138R,K153R	0.248436566223365	0.136132214403606
G23Y,N31D,G34T,M39T,K74Y,I96L,K101R,R104Q,V148L	-0.0245277209141598	0.129484122199663
G23Y,N31L,G47T,R61W,C75A,I96N,I109E,T135H	-0.165409319826888	0.110000096269789
G34A,D67G,I107T	NA	NA
G34A,E122A	0.176895885229021	0.134077113968675
G34A,E99D,N121V	0.300867695125741	0.109337610214839
G34A,K101R	0.338239597754658	0.109738748070825
G34A,N37Y	0.323998588059867	0.104225846518815
G34C,E145G	-0.108296889879489	0.0722240173071797
G34C,L120Q	-0.169813942675083	0.0267044091969478
G34D,N121Y	0.395720493231039	0.103960745435076
G34D,S95G,N121T	0.0804868505476396	0.135440193931074
G34D,T51A,F64S,A106T,I109T	-0.163500927561629	0.111523515351053
G34H,F77N,I107T,K146E	0.305459589623482	0.114336502873521
G34H,K110A	NA	NA
G34H,K59R	0.204569438169212	0.135139992732471
G34K,K74D,I107T,A131T	0.950678460101224	0.100321290236425
G34K,K76Y	0.673966667913316	0.101245279514575
G34K,N121V	0.441127752352183	0.0758471350921169
G34K,Q126Y,R147Y	0.320190407297981	0.0318954130589363
G34K,R141L	NA	NA
G34K,R61H,C75R	NA	NA
G34L,L113K	-0.0156666433091293	0.120011037988766
G34L,R141T	0.0487016959610981	0.145721918706546
G34L,W53H,A150P	0.0493938095933464	0.113283942669488
G34M,K74T,D127N	0.358858301070088	0.119276339778493
G34N,D66N,P73V,I136M	NA	NA
G34R,I125S	-0.515247290277765	0.22630809541009
G34S,A44V	-0.0252922900330793	0.0523124962996572
G34S,A44V,Q126R	0.0217648270053405	0.192325168094785
G34S,A44V,R147W,V148F	0.115123590566418	0.234165261033012
G34S,C75Q,N124S	0.117292943347166	0.146741590594763
G34S,E122G	0.0288426534816816	0.0859500028223267
G34S,E54A	-0.128805271076654	0.109859340032862
G34S,G55K	NA	NA
G34S,I96F,R147G	0.239737187348752	0.128484388616554
G34S,K74E,A106P	-0.162364819497291	0.105924744079476
G34S,K76Y	0.9554983723878	0.0978724832440058
G34S,N40S,Y87N,E122G,E143A	-0.0850189194704529	0.082692747359639
G34S,P73S,C75S	-0.225794615183478	0.0873592358471155
G34T,E42Q,D66W,I136M,R141S,V142L	0.241989215745234	0.226544264879379
G34T,K74T,E145G	-0.0575889819733875	0.121449954339768
G34V,L119S,I136M	0.197322225681776	0.104195392780522
G3A,K49E	0.506501736995618	0.10054705142264
G3E,A26D,Q151L	0.104946310597426	0.193538860500003
G3E,A44V,K65E	0.231396201838517	0.0643878947673949
G3E,A44V,K65E,E132G	0.76995121948754	0.165681192543656
G3E,A5D,H20Y,Y87D,E98G,E122K,Q139K,K146E	0.558186459204162	0.231435722276105
G3E,A5D,Y87D,E122K,K146E	0.375921061705096	0.110952407474263
G3E,D19N,A106V,A133T,K146R,Q151W	0.158349167296272	0.176912372754646
G3E,D19N,P52G,A106V,Q111R,Q151W	0.378419532800202	0.170201522026357
G3E,D19N,P52G,A106V,Q151W	0.0915645765576128	0.117921250705757
G3E,D33Y,E98G	0.201389297105736	0.106099434456628
G3E,E122R	NA	NA
G3E,E12K,K74E,E99G,N121S	1.74673157878125	0.192203946425228
G3E,E12K,K74E,N121S	0.0172900875704393	0.209504774634543
G3E,E42G,D127N	0.0192860613656953	0.0562902235460227
G3E,F155L	NA	NA
G3E,F77S	-0.165821641892171	0.0499814183495465
G3E,G34S,P72Q,K74E,P105D,L113P,Q139P,N140S	-0.363782910918697	0.207403113726924
G3E,G55V,F82S	0.577658578778488	0.209661489879956
G3E,K14R,D66E,E122M,K154R	0.85500153954288	0.141955434088244
G3E,K18R,V25A,L114S,I116L	-0.0287627003028865	0.176946942251913
G3E,K30L	0.52996909397059	0.0699448788452991
G3E,K30N,K48R,D66Y,L81A,E98G,A106Y,A131N	0.655125858535998	0.112215480019304
G3E,K65E	0.584531839057861	0.204128748647744
G3E,L113P,A133I	-0.233158224665545	0.12862413132719
G3E,N31D,P73Q	0.0916160947856976	0.159945389456645
G3E,N85K,D102G	0.0328628115618051	0.176581980269984
G3E,P105T,A133P,R141G	1.4800341529417	0.233015990741338
G3E,Q117H,V148I	0.692206411708356	0.11030412395111
G3E,Q117N	-0.0282568335419425	0.178924161763515
G3E,S7C,L113N,F155L	NA	NA
G3E,S7C,R17Y,F77T,D127F	0.946235482401035	0.159898675809917
G3E,S7R,K65L,F82E,S89P,L119R	-0.293362235326127	0.181232634776276
G3E,S7R,K76L,L113Q,Q117H	-0.393096264608863	0.228952487092829
G3E,T35K,P80S	0.164273191109164	0.169455377731451
G3E,V27A,K49E,F58L	0.257938126010607	0.132339960816379
G3E,W103M,I109V,Y137C	0.142934530725052	0.193353221565656
G3Q,K14N,H20R,N37Q,L57R,K74E,C75R,Y87Q,G90R,I107L,P123Y,D127N,V142Y	NA	NA
G3R,E132K	1.24417627545037	0.204649848355218
G3R,E42G,Q130R	NA	NA
G3R,E78D,P88H,K110R	1.5432398031829	0.166085577360061
G3R,F77L,Q111L,R147G	NA	NA
G3R,G90E,R104W,I109T,E122G,Q130R	-0.0373319165979002	0.159447370427577
G3R,I116V	0.021223136871516	0.118194700918451
G3R,K74R,R147G,Q151R	0.189325618330542	0.155882736519473
G3R,L63V,Q126R	-0.277862674110607	0.181362487255723
G3R,L9P,V27A,K49E,F58L	NA	NA
G3R,N140I	0.0570032089394661	0.118157627739513
G3R,P84R	0.168009794250702	0.098784394796194
G3R,P88H	NA	NA
G3R,Q130R	-0.184880877768399	0.115477184057018
G3R,Q130R,P157L	0.39301038317151	0.158941860346444
G3R,R13M,N31D,E98G,I109T,V142A	NA	NA
G3R,T35S,P73T,Y87D,Q117R,Y137C,V148I	0.394554035059593	0.209133171571775
G3R,T35S,Y87D,Q117R,Y137C,V148I	-0.143501849309093	0.107383246280135
G3R,V142E	0.0930911158260564	0.0367268559115951
G3R,V25E,P73S	-0.10522339126132	0.2045063459221
G3R,W53C,K101R,K146R	0.269010362042011	0.191174507021994
G3V,G115E,Q126K	-0.236698659871683	0.142978841018526
G3V,Q139R	0.553465323613729	0.114035317244162
G3V,T51N,L113P,N124D	-0.0401538982314925	0.169057883836792
G3W,F64L,D67V,T91A,W103R,F155Y	-0.108038855087452	0.104032911000586
G3W,H20Q,V86E	-0.0177817522139135	0.110892568793447
G3W,K48E,F58L,V148G	0.0495186468817807	0.119021022910473
G47E,C138R	0.138483554603507	0.0460837240319785
G47E,F77S,I96L	0.0106532152353111	0.242759445428004
G47E,K110I	-0.197946399341595	0.0751836969032307
G47E,K110I,T135M,K146E	NA	NA
G47E,K74R	0.0241895619309415	0.116959623273594
G47E,P79R,E118K	-0.121225730722407	0.0987506845634821
G47E,T108S	0.225327006390643	0.223005867537169
G47K,D67G,N121M	0.604372852949573	0.126719140456682
G47R,D66G	-0.152160108971666	0.105790102124508
G47R,P157A	0.0555080704446647	0.0682977046751363
G47R,W103G	0.00132323408294966	0.101494846812476
G47R,Y68E,K74T,S95R,G115N,I136R,R149Q	-0.162434837054702	0.212714081393735
G47T,K146R	0.233476663876826	0.102898856232177
G50E,P80L,T91A	0.30340105815613	0.106443203357744
G50N,P52L	NA	NA
G50Q,N121T,Q126R,A129V,N140D	-0.122886074407576	0.122680291995669
G50R,E78K	0.664004808474157	0.115047066181079
G50R,I107T	0.417787138402819	0.195770010297329
G50R,K74R,E122G,K146T	0.00300829123763272	0.110987752683267
G50V,I109V,E143V	0.267030313543689	0.114831884142234
G50W,G90W	NA	NA
G55D,E145M	NA	NA
G55E,K74V,I125S	0.820232452205611	0.11546930092392
G55E,T108I,I136T,Y144Q,A156V	0.195767564384082	0.180637855106103
G55K,W103R,L114T	0.0226306058214438	0.119658560884691
G55M,I112S	0.141094239708031	0.0933931521659644
G55M,P73R,I125V	-0.103034498964063	0.119649010571281
G55P,D100G,L114S,N124K	-0.131933690659661	0.196417380096472
G55P,K74G,A106Y,E132V	0.120347906839382	0.14133665664845
G55R,F77P,L113V	-0.0869847813312463	0.152286420311379
G55R,I116T,C138R	0.00563252729515806	0.0992260044421155
G55R,K146R	0.238694365975157	0.189625591492273
G55R,K65R	0.0493116855245251	0.109154579195085
G55R,L114M	0.454796571502614	0.109226032583088
G55R,M62T	0.329324397216471	0.121818919715269
G55R,P69L,I112V,L119P,D127G	0.331436456788557	0.173913017112884
G55S,F77V,Y87H,D127V	NA	NA
G55S,N124V	0.0806886887344854	0.143422047161054
G55S,Q111H,L120V	NA	NA
G55T,L119G,Y134N	0.186422257458871	0.0392478293252232
G55V,K59N	0.121728149514941	0.130669175211126
G55V,K76H,I109V,P123E,Y144W	0.163741287319915	0.0933344657050728
G55V,S89P,P128E,Y134S	-0.173931251942227	0.0863964606012735
G55Y,D66N,S89L,A152D	0.369901833792117	0.140836593492401
G55Y,I125M	NA	NA
G56A,F77L	-0.0550802123419077	0.106009403180318
G56A,F77L,I107V	0.109933240315714	0.174980819877726
G56C,F64Y,Y87H,G90V,I112T	-0.148184565695809	0.197252548764718
G56D,L63H,Q117R	-0.157321363566307	0.216213402585046
G56D,L63P,Y68N,E99G	1.05645062210882	0.150394629387866
G56D,P80L,R147G	-0.0241485656183034	0.0555356098397468
G56D,V86M,Y87N	-0.123889722207611	0.0673972075028609
G56S,E122T	-0.456773692191556	0.123980452684457
G56S,K59N	-0.210994641636704	0.119135990488772
G56S,N124T,R149Q	-0.051053314153908	0.121285517184692
G56S,Y134C,K153T	-0.314830124515155	0.111618222821678
G56V,E98D,R141G	0.37488989761471	0.0235013648440743
G56V,V86M,A129T,N140T	0.336160948498473	0.233877613957301
G90E,I96T,F155S	NA	NA
G90R,E122G,Y137N	0.0161935535257109	0.134917082948293
G90R,Q139L	-0.0750667560322452	0.0850444483649681
G90V,R149L	0.250466719730505	0.11062868819112
H20D,E99G,T108M,L120P	0.0563974506371961	0.13926870419025
H20D,N40P,G55T,Y68H,F82Y,I107E,A131I,Y144F,K154P	-0.0241227258002348	0.121625331246503
H20G,L57S,K76L,T108A,N140S	0.0873681832438642	0.107146611487697
H20L,A129T	-0.284992582197802	0.109938791781616
H20L,D33S,C75P,I112T,C138R	NA	NA
H20L,D66N,N85K,T108S	0.435811962420822	0.11308565670324
H20L,E99V,N121L	-0.435240027245966	0.188670331462327
H20L,F64S,K101E,Q126R,A131P,K146S	-0.271927312322823	0.220520422533449
H20L,G34S,Y87C,A131S	0.595199201655939	0.156594338789176
H20L,H83R,P128T,A129T,T135M	0.0853349261419847	0.148398152180305
H20L,K101E,I112T,L120R,E143G,K154E	NA	NA
H20L,K101R,G115E,N121S,R147P	0.138646995855792	0.109928940334094
H20L,K59I,K65I	NA	NA
H20L,K74E,R104S,N121T,A150L	-0.23943926408898	0.205114044606354
H20L,L38F,K49E	-0.185018490954483	0.102316817665349
H20L,L38F,K49E,H83R	0.0827189385709909	0.19932902870112
H20L,L60D	NA	NA
H20L,L94P	NA	NA
H20L,M39T	0.164799488442733	0.107424216132846
H20L,M62E,Q111H	1.26695616515768	0.113295633689277
H20P,D66T	-0.140569599668811	0.142386249442395
H20P,D67S,L120C,K153R	-0.459534794223767	0.177051910811152
H20P,F22L,F77L,A106T	0.0396156412416032	0.0987280903108296
H20P,F77K,D102G,E145V	0.204780432135153	0.113809997272828
H20P,F77L,A106T	NA	NA
H20P,K76V,I112T,E122H	0.187592388532534	0.104587638579127
H20P,M62I,L63F,D127E,T135F	0.133557633747802	0.0982843425287809
H20P,Q130K	0.139634998188185	0.102086848984352
H20P,W103R	NA	NA
H20P,W103R,E145V	-0.0964502682022365	0.137714824977208
H20P,Y87H,L113F	0.000466986259240673	0.114340099560942
H20Q,F58L,F64L,E143G	-0.116456264843538	0.0689921525984001
H20Q,F64L,Q139R,E143G	0.0123796815939486	0.257169567896613
H20Q,G115E	NA	NA
H20Q,I96T,N124D	0.338378277684799	0.134727339908373
H20R,C138S	0.358681861874599	0.11273260966244
H20R,C43R,T108I,N140S	0.359086564894383	0.22801811814725
H20R,D102G,E143G,S158P	NA	NA
H20R,D33A,K76N,P128D	NA	NA
H20R,E122G	-0.244312240382983	0.11474799050414
H20R,E78G,F82L	0.0304260677427019	0.106107688085962
H20R,F22L,D102G,S158P	1.01785761479468	0.102860806190674
H20R,F22L,I136V,C138G	0.0548653277549339	0.107638769295775
H20R,F77Q	-0.255600958156436	0.163183755480435
H20R,F82L	NA	NA
H20R,K65N,W103R,P128S,C138W	-0.171946298050934	0.0997731214849812
H20R,K65R,T108I	0.615610607595807	0.172053561431635
H20R,K65R,V92E,T108I,K110S,I136D	0.167681545941853	0.239558721512386
H20R,K74E,E99V	0.204252607667185	0.227456133458409
H20R,K76I,E145G	0.719185421564317	0.121650566219792
H20R,M36V,Y134C	-0.0259344789586044	0.103367703768655
H20R,N124G,Y144H	1.07622254065451	0.160887337106719
H20R,P28L,T35A,N40S,K74E,G90R,E99V	-0.0285021594346327	0.104841854521425
H20R,T108S,K110E	0.951748983235765	0.172400575055572
H20R,W103R,I112M,P128S,C138W	1.45744955586691	0.165736602331238
H20R,Y134D	-0.0244641801624748	0.0629150590821396
H20Y,D102N,Q139H	0.25666857977169	0.144781632848997
H20Y,E98G,Q139K	0.306713854803002	0.113681378515136
H20Y,K74I,E118T	-0.0446463424970775	0.139468296329605
H20Y,L113V	NA	NA
H20Y,M36Q,Y68N,E122G	0.166380137391109	0.10776220489508
H20Y,Q139H	NA	NA
H20Y,W41R,M62V,N85K,Q117R,Q126R,A150V,A152P	-0.271048678334048	0.117725916141577
H83D,L113V,P123G	NA	NA
H83E,D100G	-0.032707158947284	0.122071177069508
H83L,D100N,N124D,K146E,K154R	0.133175995914197	0.173559752902883
H83L,E132G,Y134H,I136T	0.186863761320085	0.211448797135807
H83L,I109K	NA	NA
H83L,I109T,A150V	-0.0405415973395724	0.0982670597330142
H83L,N124D,K146E,K154R	NA	NA
H83L,T91I,E122D	-0.00390139699733316	0.0557903870406993
H83N,I116V,N124K	NA	NA
H83P,E145G	NA	NA
H83Q,C93R,K101M,L113F,A133H,E143I,K154E	-0.26792834251543	0.159147237786036
H83Q,I109V,T135M	-0.0259356648507829	0.116960548557578
H83Q,L114T	NA	NA
H83Q,R104G,N124G	-0.704933741090087	0.237163138432624
H83R,I136V	0.00894268330647832	0.265308033888387
H83R,L94P	NA	NA
H83R,N121S	0.149206057242212	0.109570523886994
H83R,N140D	NA	NA
H83R,P128T,T135M	0.400314447253353	0.188267491150251
H83R,Q111R	-0.0103797988478634	0.106952065829042
H83R,S95P,A131V,T135S	0.410026994608013	0.106821608543977
H83Y,Q111H,N124Y	0.0211507579517215	0.102232054445334
H83Y,Q130R	0.1216766127964	0.119430751188229
I107A,I136V	0.847387792016676	0.10930641770427
I107E,I136S,Q151R	0.529858577772507	0.132160324768528
I107F,T108A	-0.0785305141098196	0.111328715373735
I107F,T108A,R149Q	0.548675347784108	0.179262084089629
I107F,T135A	0.908523184028601	0.144165194852674
I107F,Y144S	NA	NA
I107G,E122S	NA	NA
I107K,N124R	-0.194470534592551	0.18721334318629
I107K,N140S	0.138941685720264	0.28463224695426
I107N,L113I,I125T,R147L	-0.447417219405387	0.191961333693473
I107T,E118V,Q126R	0.813044312017592	0.116548484957044
I107T,E132A	-0.344457317503249	0.249996970478859
I107T,E132G,A133P	-0.0779913527071804	0.107243434088593
I107T,K110E,P157T	0.312371236529469	0.107742796025804
I107T,K154E	0.509774561630766	0.103966396586381
I107T,N121H	-0.00756957537680143	0.0906182545850209
I107T,N121V	-0.196858679670591	0.169375599525555
I107T,P157L	0.0905336770482826	0.200871248853502
I107T,Q126R	0.721048545310424	0.115932247279472
I107T,R147G	0.176885378449044	0.0994979689773654
I107T,R147M	0.6202923111499	0.108464741507175
I107T,T135A	0.956205009230985	0.101053522153554
I107T,Y134C,R147G	0.315302829799702	0.182044992765654
I107V,K154R	0.983994221425947	0.100520340496695
I107V,Q126R	1.81930259620893	0.127949298407197
I107V,R147G	NA	NA
I107W,N121H	NA	NA
I109F,I125R	-0.0916262700015185	0.110507243901304
I109L,P128S	0.393605585150649	0.0473576061001567
I109L,Q126P	NA	NA
I109N,Q126V	0.421511992561564	0.10062845641034
I109R,K110E,A150C	-0.111396089125275	0.166525049265509
I109R,V148P	0.0155362660535872	0.160192279619701
I109T,A152D	0.453316826384685	0.141584691165952
I109T,P123T	0.275522797590928	0.133010066726213
I109T,Q111R	NA	NA
I109V,A152D	0.123434728698323	0.118164244549304
I109V,I112A,L120P,F155L,P157R	0.092277253686461	0.190258127422414
I109V,L120I	0.145444915095829	0.170261995112291
I109V,Q111K	1.31524928052697	0.107709504896415
I109V,Q130P	-0.0404808354381745	0.0978815726299318
I109V,Q130P,V148L	0.430291149449243	0.228769718584354
I112A,E145G	0.538321830268631	0.185421643340212
I112A,I116T	0.038171330390717	0.12931225064648
I112F,Q126V,P157S	0.135115570974864	0.162094451166645
I112F,Y134H	0.539449498655145	0.0997748101753483
I112G,K154N	NA	NA
I112K,E122H	0.410543004445058	0.179840774797833
I112L,I125T	0.573097643510972	0.134663846713904
I112L,Y137C	0.474708901733997	0.105400238922797
I112M,E122G	0.638431424682028	0.100462684422158
I112M,N121D	1.94896562630398	0.112046821515833
I112M,N124S	0.58842401610701	0.145926076839422
I112N,A156T	1.31436439992105	0.197083582729561
I112P,N121L,Y137C,Q151L	0.0881887932018699	0.14155542663539
I112P,T135I,R147A	NA	NA
I112T,A150G	1.45491354598164	0.0990695716086306
I112T,A156T	2.35675224939635	0.197464808641798
I112T,C138R	-0.131260047879371	0.207897920498441
I112T,D127G	0.652456600655035	0.100565868950976
I112T,P128S,Q130R,Y134C	0.902951164644455	0.133080826209861
I112V,A152D	2.31010010944753	0.139852739672656
I112V,I116L,P157S	1.50573476412902	0.119693065486898
I112V,I136T	0.893005551828841	0.178811252175478
I112V,L120D	-0.0145365657059552	0.183436551010917
I112V,P128T,Q130L	0.0287803556228396	0.112939047623479
I112V,P157L	NA	NA
I112V,R141G	0.163560938157485	0.0668335368525912
I112V,V142E	1.35151428460052	0.105219001121266
I112V,V148G	-0.0541128390213412	0.0469931613619885
I112V,Y144F	0.0322902266650808	0.214843345723836
I112W,V142L	0.140229961315308	0.114657752299879
I116L,A129S	0.00934854850771647	0.0863515221477293
I116L,K146R	1.82181500571586	0.279262606318444
I116M,E122A,Y137K,K153E	0.361089288574608	0.157368016014468
I116M,N124Y	0.363900343714656	0.110129549343427
I116M,Q130R	0.336874791015071	0.107623545691666
I116T,E118G	1.21296725572828	0.145031892563994
I116T,E118G,C138R,K146N	0.411326371517583	0.176316510917037
I116T,N121S	0.522671548670684	0.120492334665205
I116T,N124Y,K146E	0.0589132816840825	0.0685625747031875
I116T,T135A	0.299446721606203	0.120861280865134
I116T,V142A,E143G	1.30153033643891	0.169216457626057
I116T,V148G	-0.0599915839050595	0.563119767000764
I116V,N124S	0.27772165859987	0.111558691425875
I125C,V148A	NA	NA
I125F,A129V,A152D	0.24129422032693	0.17700592508388
I125F,A152D	0.158960147470208	0.103692385452264
I125F,Q139H	NA	NA
I125F,Y144F	-0.109884242586608	0.102542071853122
I125M,Q151R	NA	NA
I125T,D127G,Y134C	-0.0264102518165041	0.129302101510981
I125T,F155L	0.219064637838877	0.121959854411247
I125T,Q126R,E132K,R141S	0.358207738110348	0.205350798785922
I125V,T135A	0.433791660880586	0.107265403964621
I136A,E145G	-0.178731362928496	0.205426441937386
I136F,R147G	-0.0288941453036862	0.169519160980088
I136T,E145G	0.415777927043197	0.151656705414714
I136T,F155L	0.139894411989559	0.0665731957374035
I136T,K146R	0.61877258276051	0.122192263448003
I136T,S158L	0.291858751242456	0.0424699762879099
I136T,Y144Q	-0.209280847305118	0.077821236609908
I136V,C138G	0.182873312965217	0.154293844039878
I136V,Y137S	0.180639556570553	0.147562068913027
I45A,K48E,L63P,L97F,R147G	0.105677346908178	0.111714297515297
I45F,F58C,K59N,E99V,V148I	NA	NA
I45F,G90R,N124S,T135A	-0.170378577997275	0.111031685731199
I45F,K101E,E122G	0.384320493598435	0.119608567042512
I45F,L57W	0.445711177382828	0.285771370977965
I45L,K154E	0.129273741335918	0.111104543232902
I45L,Y87H,A150N,K154E	0.47259841631717	0.188494045183436
I45N,E54V	-0.189888573195977	0.0500693755470775
I45T,A150T	1.1684926342033	0.152150487934189
I45T,D67G,T108R,I109T	-0.219644869165402	0.139221937266958
I45T,D67T	-0.0503417727045112	0.108956918667995
I45T,E145K	0.0393683425653632	0.103687193187932
I45T,E54Q,M62L,H83R	-0.164796841243425	0.101878004125761
I45T,F58W,M62R	-0.0580228947992049	0.139675191276536
I45T,K110Q,Y144S	0.149008728878814	0.114075855239826
I45T,L119F	0.0922186162392516	0.0547648491221052
I45T,L57V,D67T,A106P,I125N	0.391729268220273	0.103052471661435
I45T,S70P,P73S,K110G	NA	NA
I45T,V92L,I96N,R104G,E143G	-0.172194512863717	0.110680360217698
I45T,Y134H,Y144F	0.0668159692435038	0.0901491494901043
I45V,E118G,N124R,R147G	0.0997375867621857	0.0661333148807387
I45V,E98G	2.47624911487277	0.117364014551135
I45V,I116L	1.74774864238921	0.20638937668005
I45V,K101E,L119P,N124Y	0.549684677270509	0.187470603108215
I45V,K74R,E118G,P123S,R147E	-0.1797392323103	0.11237878273874
I45V,L119P	6.14102980299144e-05	0.173580116263937
I45V,P46L,G47R,I136R,R149Q,F155Y	0.803873092468777	0.127101063256192
I45V,S71L,N121S,F155L	0.580133848113499	0.100441902022506
I45V,S71L,N121S,N124K,F155L	1.44732388570712	0.20038446749599
I4F,D102N,E122D	0.624301962582238	0.101242450496153
I4F,E122V	0.0885833050072726	0.124402825482167
I4F,L81I	0.592830872258327	0.10689948481168
I4G,F24S,T35A,N40D,E118V	0.184760312698698	0.103516207442665
I4G,M62W,R147T	-0.599410759822921	0.363898203895282
I4G,P128S	0.19446481728367	0.103648827563888
I4G,P128S,N140S	-0.00806223512423667	0.330346728656814
I4G,P72Q,S89T,P128S,R147G	-0.294318802155552	0.129646658846543
I4G,R8G,R13W,F24S,P80R	-0.238269423672343	0.135150635670207
I4L,I45F	-0.284802840101727	0.114887874517765
I4L,I45F,W53R,S70C	0.448150902945734	0.195460453105301
I4L,L6R,Q126R	-0.015859628715232	0.0999474406329641
I4L,M62T,G90V,Y134C,R147G	-0.271104633008604	0.166079580791207
I4L,V92A,Y134C,R147G	-0.547232664939365	0.258256180302995
I4M,M62R,G90W,K101M	0.124828078883765	0.136685831348769
I4N,I107V	0.541391039701116	0.128086302094079
I4N,I125T,Q130L,C138W	0.200631037333392	0.155039377427776
I4N,I45F,W53R,F64I,P69S,P80S,A129V	NA	NA
I4N,L6H,N40D,F64L	0.278929538062452	0.154321559680434
I4N,M36K,N37I,K49E,N140S,E143G	0.22322601294681	0.221795816965216
I4N,T135R	0.214300709864752	0.129336504393559
I4N,V27A,Y68H,F82L,A156S	0.512036565303564	0.180386605839349
I4N,V27A,Y68H,V86A,I96V,A156S	0.98188075423416	0.151258699421547
I4S,A131G	NA	NA
I4S,A133E	0.0619887852680161	0.125204521454407
I4S,A5G,K48R,E78G	0.0370391280326355	0.102864243961244
I4S,D100G,D102G,V148D,K154R	2.54664723356392e-05	0.103211610208345
I4S,D127G	NA	NA
I4S,D19V,L81S,C93R	-0.142459164459843	0.120653382122869
I4S,D67A,S71L,P105A,I109T,E122A,Y134C	NA	NA
I4S,E42G,A106V	0.392253201421046	0.119609844791294
I4S,E54V,N85D,Y87F	0.156039706739823	0.107665951709055
I4S,F155L	-0.0907471335113021	0.135896417070426
I4S,F24S,A44S,T51A,P73L	-0.128215533065219	0.10382116227433
I4S,F58S,I136T,F155L	0.768025268226631	0.15330373281383
I4S,F82L,Q130R	-0.0017761687194952	0.11251459330598
I4S,H20P,R61A,H83Q,L114T,S158M	-0.169519370136454	0.121810356205577
I4S,K146E	NA	NA
I4S,K14R,L113P,T135M	-0.018282737099148	0.114837921011347
I4S,K18I,V27I,D66G,Y144C	-0.401057572910276	0.108133655202067
I4S,K30N,V142M	0.751875164840434	0.168528896601343
I4S,M39V,I45V	1.58262643410989	0.14599635805212
I4S,N121D	0.978704705408417	0.0974014544893857
I4S,P105L,Q139L	-0.0876914360087359	0.100438159865801
I4S,Q139H,Q151R	-0.146827386683237	0.140326514585827
I4S,R17Y,K30R,P79Q,T135N,N140H,R147G	0.131919943759589	0.119607026027674
I4S,S71P,I116M	0.120586700868192	0.11169850576496
I4S,T29P,T51A,P80L,D100E,A106P,I125F	0.165202439075437	0.187522420621127
I4S,T91A,R104S	0.90502154407141	0.101822688187912
I4S,V25A,K48R,S71P,C75F,N121S	-0.217120953617774	0.104693286190245
I4S,V86M,F155S	-0.196392167296725	0.207633708219926
I4S,W16Q,T35S,N37D,K153M	1.45795073095601	0.202716598237114
I4T,A15G,C138R	1.34065476965018	0.215222611603917
I4T,A5T	0.0308509949013674	0.141964036468397
I4T,D33R,K49N,Q111R	-0.180014014843476	0.121279887527315
I4T,D66G	0.516152998557705	0.183894452897259
I4T,E143K	0.23139274100815	0.160285122002329
I4T,F64L	0.724202798378058	0.115650158573465
I4T,H20Q,I45T,K101E	0.287532051877446	0.196744598228915
I4T,H20R,V25M,K59E,M62L	-0.0501328458643013	0.0988219728540019
I4T,K110Y,Y134G	-0.171418694501968	0.106188430893298
I4T,K18E,D66G,F77V,E145H,F155M	NA	NA
I4T,L114S,C138Y,F155L,S158L	NA	NA
I4T,L9H,P32S,M36V,G55R,P72L,N85D,K110N,Y144K	0.335152842212108	0.164854674958639
I4T,M39I,P72A	NA	NA
I4T,M39I,P72A,E143G,A152G	0.503554240760302	0.224886854050591
I4T,N31I	NA	NA
I4T,N37D,P72A,T135A	0.632834147108486	0.182368586718383
I4T,P69S	0.836497965809201	0.106616464440334
I4T,P72A	0.754154734301559	0.196848214208452
I4T,R13G,E98G	1.87692827622379	0.185160398211682
I4T,R8G,D102N	-0.305309608981675	0.124573064124342
I4T,S95P,R147G	NA	NA
I4T,T108S,R147G	-0.0412704139856995	0.117651474705651
I4T,V25G,D33R,K49N,K59E	0.2346928103203	0.104844449501708
I4T,W103V,E122L	0.1403481450701	0.115091858930131
I4T,Y144S	0.0702782806359534	0.189950584768365
I4V,A129P,C138S	-0.0424761390601461	0.0893192931598384
I4V,C75V,I107F,Q111E,Y134H	0.131858469252694	0.117831107333177
I4V,E122A	0.237192348980684	0.106254558853278
I4V,F22L,N140H,A156T	-0.0304933406620307	0.193778276507103
I4V,F24S,T35A,N40D,E118V	0.0209224869317668	0.117675203243454
I4V,G23D,K49R,S95P	-0.0248070608371149	0.413476518248847
I4V,I136V,E145V	-0.26521634529073	0.112941925981979
I4V,K14R,D102E	-0.0120346564356933	0.106171993657015
I4V,K14R,K74R,D102E	0.256902714969749	0.1078702276699
I4V,K76E,L81A,I109S	0.530074173916091	0.158526355826524
I4V,L63P,P128S	0.680325131385262	0.148743443845428
I4V,M62W,R147T	-0.170087079599417	0.111391289655948
I4V,N37S,C93Y,D102G,I109N,N124S	0.370400336982254	0.169051320323779
I4V,P128S	0.0891528258427366	0.111765746332646
I4V,P157A	0.153251185817487	0.134037470035441
I4V,P72Q,S89T,P128S,R147G	0.0563576944908848	0.0978565103750537
I4V,Q139L,K154M	0.102754050767287	0.158701877390331
I4V,Q139L,K154M,A156E	-0.648233327982254	0.25055036611919
I4V,R147K,A152P	-0.231437120723022	0.105253681667669
I4V,R17D,D19G,L81D,Q130T,E145L	NA	NA
I4V,R17E,D19G,K59R,L81E,Q130T,E145L	NA	NA
I4V,R8G,L9P,K14I,F24S,N37D,D102G	0.0601856264651337	0.201365603915318
I4V,S7R,E78G,W103I,R141T	-0.276629432101722	0.145780797383814
I4V,T29A,K30T,P72S,E143K	0.778357068025533	0.114454365091597
I96F,N121L	0.228221262938431	0.113484393875265
I96F,Q126R,R147G	NA	NA
I96T,A133V,P157A	-0.475746656436162	0.224666886885861
I96T,D127L	-0.166304130613354	0.100095350978918
I96T,I109V	NA	NA
I96T,R141G,K153E	0.993017429396756	0.0995315289475935
I96V,A156T	1.27768161244189	0.150933236593428
I96V,D100G	0.903710291907163	0.154085153960535
I96V,D100G,V142G	NA	NA
I96V,I109V,Y144A	NA	NA
I96V,I136V	1.88274409097769	0.118614806006191
I96V,Y134C,Q151P	0.0886584237446169	0.133196258119413
K101E,E122V	0.344182945443491	0.11739208992773
K101E,I112L,A150V	1.13183895392479	0.121531939155341
K101E,N121K,N124S,Q126L,D127V	NA	NA
K101E,N124Y	-0.540079646545964	0.248210147738955
K101E,N124Y,A156E	1.46934334113894	0.128844918478217
K101E,P105L,K146E	0.457505810934607	0.234222070963381
K101E,Q111N	2.06156875036123	0.205972733306812
K101E,Q111R,A129P,S158L	1.41333751996823	0.544369025549798
K101E,Q130R	0.566619385986921	0.244224363353977
K101E,R104S,R141S	-0.343285761878276	0.120978303553614
K101M,L114S,P123S	-0.0696927388485588	0.0166973552496037
K101R,A106V,L119P,Y134H,A156V	-0.182947287973913	0.244105877924563
K101R,E122I	-0.459352534465939	0.304201694758735
K101R,K146N	1.67915844404716	0.169106109114151
K101R,L113Q	0.364800581325427	0.108346674465711
K101R,L114S,K146E	0.918743906865911	0.163417677305136
K101R,N121K	NA	NA
K101R,N140D	0.175682540758686	0.215742245451477
K101R,Q151R	-0.020948021428687	0.0942477311132401
K101R,T108S	0.584474567331178	0.218729313896617
K101R,W103R,Q151R	0.101889661676503	0.39076309236271
K101Y,R149Q	0.687118547328864	0.260383646860768
K110C,E122L	-0.544243817154302	0.190653533594584
K110E,E118K	-0.191610786348337	0.168585606664827
K110E,I112V,K146N	NA	NA
K110F,A152C	-0.147840882094888	0.121486665376501
K110I,E118G,T135M	0.684970994016378	0.267558479164505
K110I,L114I,N124D	NA	NA
K110L,A131V	0.0345462260115276	0.133407083227367
K110L,N124P	NA	NA
K110Q,L120M	0.37976938113722	0.125213966445104
K110R,A133D,R147Q	-0.0265922858951235	0.189251898718878
K110R,A133S	0.614579913438359	0.100968510664211
K110R,E143S	0.0299629986524156	0.108539372961347
K110R,I116V	0.704485897800886	0.100439766326749
K110R,K146I	0.776572186464773	0.10354697804824
K110R,L113F,Y144C,F155Y	0.628122583731989	0.159359675272028
K110R,L114I,N140D	0.467773808899111	0.104936130298312
K110R,N124Y,K153R	-0.25589768799228	0.14362436200047
K110R,R141C	0.116722639078419	0.184842652144125
K110R,Y144C,F155Y	-0.174085382171227	0.116874026179022
K110S,A150W	1.21822331570508	0.111195999800702
K110S,D127A,A156L	0.179670631158993	0.109389743692171
K110S,Q139H	0.107431811656116	0.104633020413246
K110V,Q130L,E143G	-0.0884714653325639	0.171148212457927
K110Y,E118D,V148K	NA	NA
K110Y,I125G	NA	NA
K146I,P157H	0.518747815877302	0.107862892542252
K14A,D33H,R61G,Y68A,I109G,D127G,Y137S,F155R	0.215437112614899	0.126780199109462
K14D,M39L,F58S,D66L,Y87Q,Y137S,S158E	0.441606348531469	0.10534621256736
K14E,A15G	0.622025472566723	0.277221296951551
K14E,C75S	0.524896099009782	0.108446336371399
K14E,E118G	NA	NA
K14E,E99V	-0.144615969815107	0.0481383121925367
K14E,I45T,N121D	-0.0547629464690462	0.113626534848803
K14E,L38I,I109A,I136V	-0.0123688659035306	0.114857608494578
K14E,L38P,K59R,L63P,I112V,E143Q	NA	NA
K14E,L38P,Y134H	-0.136382678034798	0.117329678914548
K14E,L81C,D100G	NA	NA
K14E,L94I,D102N,K110R,N121D,Y144I	0.372974533799651	0.177127780683431
K14E,M36I,L63F,G90W	NA	NA
K14E,M39L,V142A	0.169073290770268	0.135877645656943
K14E,M39T,P73Q,I96T,T135M	-0.0831042746371031	0.119960264936953
K14E,M39T,P73Q,V86A,I96T,Y137F,R149L	0.112180087205863	0.214580259927839
K14E,P32T	NA	NA
K14E,R17G,K30N	-0.0379138786911306	0.106613561966036
K14E,T35A,F58L,Q111R	-0.21656956968892	0.151127766638408
K14E,W41C	-0.112758141446463	0.118238283391549
K14E,W41R,C138Y,Q151R	-0.0545718152260329	0.151573173631682
K14E,Y137F	0.693751681073968	0.144858055340473
K14G,H20L,M36I,K48E,L63F,G90W,I109T,Q111R	-0.434979767565809	0.194618528116631
K14G,I109V	-0.173505909201572	0.342562189132257
K14G,L94R,I107E,L120E	-0.17571365957688	0.132108322188598
K14G,L94R,I107E,L120E,R147I	NA	NA
K14I,G23S,P28S,T29A,N85H,N140D	0.063910400784922	0.121891361643961
K14I,K18R,N37D,Y87H	0.37690572380579	0.210671898343302
K14I,K48E,K65N	NA	NA
K14I,K65R	2.13396600138919	0.186173092535887
K14I,K76R	0.390170152901722	0.19837697226479
K14I,L94Q	-0.0979885364967105	0.111633053697486
K14I,P123T,Q151R	0.269841660327879	0.207649085596784
K14I,P84T,K153E	-0.0451426183140731	0.120439882736084
K14I,Q126R,C138N	0.0763227575459358	0.156554673717511
K14I,T51A,C138R	-0.245810427611573	0.118365005007012
K14I,Y87N	-0.0239329304297814	0.0655343428564566
K14L,N31L,R104N,L114S,C138R,A150K	0.16738184328131	0.160678393139329
K14M,S70P,E78G,V86A,C138R	-0.201180779614721	0.282719595352049
K14N,D19G,M39V,L114R,A129L,E145Y	-0.120370222090193	0.101672454217486
K14N,K76P,E143V	-0.200951967326181	0.164443194254344
K14N,L113F,Y144D	-0.0355775795327677	0.154985629937753
K14N,N37D,K48T,P73S,K74E,Q111K,N121T,N140K,A152G	0.86987996691774	0.168928077173526
K14N,P21R,L113S	0.231736338403213	0.123620478199604
K14N,P46Q,K65T,A129K	0.101983971930171	0.0981498301705749
K14N,Q117H	0.223789993357504	0.099314195856604
K14N,T35A	-0.103833161644002	0.0454050210410489
K14N,W53R,S70C	0.381755753857444	0.111569161726629
K14P,G34S,L60T,K76N,L119N,Y134R	-0.12217285255841	0.10910658377395
K14R,A106V,K153Q	0.0318470436285329	0.220725529589236
K14R,A131T	1.19011219615989	0.103591904395446
K14R,D33G,M36I,K59R	0.0462703707542424	0.212102615971525
K14R,E118G,A131T,K146N	0.0167959418358426	0.237656546852771
K14R,E143G	0.562793035828614	0.185443396526547
K14R,F24S,M62I,I96T,K101R	0.428578914548061	0.260139991115854
K14R,F58L,M62T	1.09352852115319	0.112895085987082
K14R,G47P,P84S	0.233651173895889	0.112898749608665
K14R,G56D,Q151R	-0.117920881304529	0.182800720013889
K14R,H20L,K48E,I109T,Q111R	0.0841877484278479	0.0751777529620672
K14R,H20R,D67G,K74E,K101E	0.62477949063081	0.156068148194927
K14R,I112T	1.2814688771035	0.319461983685631
K14R,I125F	1.21725982828126	0.16681760099119
K14R,K153Q	2.05622393144253	0.110968232320908
K14R,K30R,K101E,V142A,Y144C	-0.0812342406676686	0.11030520353987
K14R,K30R,M39V,K101E,V142A,Y144C	-0.351090816544591	0.210109312567912
K14R,L113P,T135M	-0.14534210386673	0.189977661507071
K14R,L38P,I112T,Y137S	-0.0648268874265832	0.110543873110455
K14R,L94P	0.105837990477115	0.0885540095390886
K14R,M39V,F155I	0.236306414377643	0.113949489395149
K14R,N121S	1.25071985550614	0.211412539327796
K14R,N31Y,N40D,A156P	-0.0585052346978994	0.195985836916805
K14R,N31Y,N40D,P69L	-0.18223064611066	0.106119595366416
K14R,P72Q,Y144D	0.128943634302968	0.112308427742659
K14R,R17W,I112T	NA	NA
K14R,R61N,I112N,R147K	-0.0161261594971539	0.177286792315928
K14R,S95P	NA	NA
K14R,T29F,C43K,F58W,Q111R,E132S	-0.0783657471638491	0.117469312681105
K14R,T35A,D100G,I116R,I136T	NA	NA
K14R,T35A,Y87N,V92M	0.469452737750684	0.111847549037236
K14R,V25A,W53R	0.0637403691814769	0.101850691375913
K14R,V27A,D67G	NA	NA
K14R,V92M	-0.41052826189651	0.173399390320926
K14R,W16N,K76S,R141G	-0.300553798563797	0.126631467933014
K14R,Y68N,A131T	1.08082976454079	0.212363537654897
K14R,Y87C,E99D,R104G	0.118955844691878	0.37695948689322
K14R,Y87C,R104G,I107T,T135M	-0.12506010955754	0.108605323371913
K14R,Y87C,R104G,T135M	0.881752869891654	0.0995260238600696
K14S,T35E,M36I	-0.37837327145214	0.127324730048515
K14T,K74L,A156G	NA	NA
K153E,P157S	1.4025418438174	0.116723191828504
K154E,P157L	0.799837241380846	0.157756867616183
K18C,D66T,A106S,E143G	0.254759792142548	0.107117154037194
K18E,A133V	-0.101249087386865	0.136859081966594
K18E,A152T	-0.263917597615218	0.0976370928077718
K18E,A156V	-0.0854610118501585	0.105124244035046
K18E,C138S	0.583663849651986	0.240105332074942
K18E,C43R,T108A	0.442057903821813	0.0988960302957038
K18E,D127S	1.08125937490987	0.107062500308324
K18E,D33E,A133V	0.331118856973053	0.139504117710578
K18E,E122G	0.196751935338196	0.105405493011284
K18E,F24K,K65E,L113I	-0.151563780632772	0.0599671387537312
K18E,F24K,K65E,S70P,L113I	1.12771568987064	0.202368032922362
K18E,F24L,K101R,A106V,Q139R,Y144H	NA	NA
K18E,F24S,T108I	-0.0282761985495423	0.125218882190527
K18E,G47E,H83D,E98G,K110I,V142G	-0.287052927056494	0.155728485281123
K18E,G47E,K48R,P80R,S89P	0.0381025753112319	0.0671916752764517
K18E,G50R,E98D,R104K,L120P,E122K	-0.185406510118542	0.28342943183884
K18E,H83D,E98G,V142G	-0.0350610481291496	0.117685537768343
K18E,I116T,N121S	0.849968777694105	0.22458640854003
K18E,I45V,N85S	-0.0881690133629406	0.120776056960776
K18E,I96T	-0.103306292614486	0.113938315551468
K18E,K101R,I107T,R147G	NA	NA
K18E,K154R	0.00255020401241165	0.132764379397181
K18E,K30R	NA	NA
K18E,K59A,L63R,S71F,Q111A,Y137S	0.0349142121779666	0.143086726976764
K18E,K74T,E145G	0.652210366578574	0.104547882803389
K18E,L97S	0.13679551548574	0.100696411048513
K18E,L97S,D100G	-0.333486179726965	0.209242454938172
K18E,M39I,F64L,R104G,Q117H,V148A	0.451003128395054	0.158138656448373
K18E,M39I,Q117H,V148A	-0.111741299613653	0.0830547438821301
K18E,N37S,P157L,S158P	1.38723885082068	0.341781307629341
K18E,P157L,S158P	0.0742718037706701	0.120711793377967
K18E,P21S,L97S	1.10556907698995	0.172663608779228
K18E,P69C,P80L,R141F	NA	NA
K18E,Q111H,C138R,K146D	0.860006709529034	0.221996282331575
K18E,Q111P,A133V,F155S	0.310360065194685	0.179112134695747
K18E,Q126L,Q139L	-0.0142456092218696	0.131913254063865
K18E,Q130R	0.0323771229267314	0.104425526966242
K18E,R61Y,Q117D	0.0992359614070967	0.104982455937286
K18E,W53R,Y68C	0.135211068181259	0.0916855893508523
K18E,Y137N	-0.0428289349338429	0.140108165075892
K18F,R61Q,K110R,K146M	-0.300748217177393	0.179271376303939
K18G,P28N,F64S,P72V,S95V,I109L,L120I,T135G,K146S	-0.104717885575451	0.096432581799141
K18I,I107T,Q126P	0.0304662436950403	0.0586657839341792
K18I,V27I,D66G,Y144C	0.0140122234294756	0.0525262895477629
K18M,L38I,G50S,M62I,K76C,I107W,R141M	0.00973829261723869	0.0770698113521245
K18M,P84K,Q126E	-0.588614940674804	0.118933943054248
K18N,A26G,T108A,I116V	-0.0776252117166451	0.20021990074083
K18N,E54G,F82L,I125T,Q130H,F155L	-0.0237673496748652	0.109247287406231
K18N,I107V	0.723327838376439	0.217329215375365
K18N,K49E,P80L,N124D,R147G	-0.271052210207321	0.105790535815171
K18N,K49E,P80L,V86A,N124D,R147G	0.133342818875353	0.149746368812602
K18N,L81S,K101E,R141G,Y144H	0.422338253329322	0.233439556352581
K18N,L97S,I107V,Y137F	2.11327514018783	0.2223664980478
K18N,T91A,I109T,Q111R	NA	NA
K18N,T91A,K101E	0.0468725966342393	0.145028623722628
K18N,T91A,K101E,N140D,E145V,F155I	0.376935704261056	0.127882333481433
K18P,A131G	-0.00396945592060497	0.192411642011815
K18Q,K110E	0.509464232636616	0.196178005128785
K18Q,L60M,K76T,P105Q,Q126W	-0.0906894094720089	0.122552427038377
K18R,C43R	0.633270989767275	0.330260134951072
K18R,C43R,E122R,K154A	0.157022766460975	0.193010400494407
K18R,C75R,R147G	0.154005304062932	0.161636258835545
K18R,D100N	NA	NA
K18R,D67R,K110Q	-0.0242142744420737	0.0585536502747104
K18R,E54K,L63P,P79S	0.517097113741773	0.170837569271735
K18R,E54V,D102E	0.837737694140042	0.218721853333787
K18R,F24I,A26T,W53R	-0.088394329155804	0.0410636089712803
K18R,F58L	-0.175185903579957	0.111665274771061
K18R,F58Y,W103G	0.698085600071469	0.221702377436137
K18R,F64L,C75Y,F82Y	0.1083533184839	0.11130511463509
K18R,F64S,V92L,L114S	-0.343691863385913	0.209614422087366
K18R,H20R,D102G,I112P	0.730597331588078	0.186451716547153
K18R,K65E,D66V,E145K	0.236052312507272	0.0939518303642701
K18R,K74R,P84S	-0.16860613602831	0.0855813885178262
K18R,L114S,I116L,Q130H	2.71382290094965	0.214635831358945
K18R,L120F	0.440633212780288	0.150541771502332
K18R,L63P,K146R	-0.0340650806474324	0.133143942271802
K18R,L81T,Q117L	-0.0309349120117476	0.111911826702834
K18R,N31S,V86E,R104G,P105A,L114S	1.54901282682087	0.111407535026577
K18R,N37M,L60K,P84Q	NA	NA
K18R,Q117R,R147G	-0.47650157095434	0.212382880670138
K18R,Q126R	1.01340065818732	0.132332918954528
K18R,R141S	0.242313496180656	0.230831613400225
K18R,S95F,Q117H,Q126L,T135A	0.0133492678217181	0.125541890882319
K18R,T108A	2.55396786353804	0.180417377142244
K18R,T135A	0.34820483210194	0.186669221997811
K18R,V25M	NA	NA
K18R,V86A,R147K,V148A	-0.146082948414869	0.0619416318090364
K18R,W103R,F155S	-0.123027649214801	0.110513861162661
K18S,F22S,C43R	0.0096825710080487	0.0744461739396384
K18S,K65E,L113F	0.309124754649732	0.129960138259378
K18S,N37L,L114T	0.633377141697081	0.102922601856327
K18T,D19G,K65R,S95T,E98G,Y137H	0.221368606873572	0.0245429747919489
K18T,D19G,Y137H	NA	NA
K18T,K76A,I107F,L120G	-0.129570485514389	0.135670375534403
K18W,L38G,R61F,C75G,C93S,W103Q,L119R,Y134D,R147G,S158L	-0.0224252479562158	0.111247415158581
K30E,D67G,F82S,V92A,Q111L,I136V	NA	NA
K30E,E54V,I107L	0.410413504692956	0.0727324992496952
K30E,I96T,A133S,V148M	0.264060261089275	0.171406969719608
K30E,K48R,K49R,V92M	0.389940419294324	0.147364863863793
K30E,K65R,E78G,G115V	-0.105114516476511	0.11597533617109
K30E,L113W,D127G,R141H	-0.0822420555623968	0.113358586404535
K30E,L63P,A150V	0.0737847264147373	0.139231154924724
K30E,M62K,E145G	NA	NA
K30E,M62K,K110N	0.191410599904765	0.232025387366439
K30E,M62K,T91I	-0.140463497102485	0.186069208304539
K30E,N37S,A133V,R141K,R149Q	0.249880617685624	0.247714675539053
K30E,N37S,R149Q	0.163141823388148	0.110903204558069
K30E,N85S	-0.101192014934833	0.114097990161231
K30E,T35M,N40S	-0.248245979247334	0.171798819027022
K30E,W53R,M62K,F77S,L94P,F155L	0.474974636735771	0.24668467843673
K30E,Y87C	-0.155178306396481	0.109952175058939
K30F,N85S	0.296926155560333	0.1043240498368
K30I,C43Y,E98G	2.90234041175413	0.156414567253973
K30I,E98G	1.82862037281658	0.132794363109164
K30N,S158T	0.0343605331226269	0.131435463742367
K30N,S70P,I116T	-0.10588334363809	0.10957016610194
K30N,S70P,L81S,I116T	-0.169556885621794	0.120485361324587
K30Q,R149L,F155S	-0.0594457397561484	0.163455082645047
K30R,A156G	0.668533291596689	0.100407650752495
K30R,A44T,L57S,A156G	0.513156133941372	0.167646632334394
K30R,E118V,L119P,T135M,F155L	0.353548150797492	0.170760407566895
K30R,E145G	0.139314690066993	0.113450981922382
K30R,E42G,S70P,L113F	-0.448285879191795	0.167052361662975
K30R,E42V,P73S,T91A,L97F,P105S	0.338330479841079	0.117478208315663
K30R,F64S,K101E,Q126R,Q139L	0.184819291175319	0.152392028232177
K30R,F77L	0.0577351171782517	0.130166492347817
K30R,F82L,N121D,N124Y	NA	NA
K30R,G55R,M62T	-0.0125328990626164	0.108251080249828
K30R,K48E,T51A,P73S,T91A,K146R	NA	NA
K30R,M36I,K49E	0.596408182836772	0.0992769879643884
K30R,M62T,L63P,V86G,A133V	0.172172722611684	0.134523195829406
K30R,N124Y	0.271962422211129	0.10019336606474
K30R,P32S,N37D,K48R,W53R,M62K,F64S,Q139L	1.00978864870619	0.120893705563758
K30R,P73S,T91A	0.230154685957657	0.105873278223925
K30R,R104V	-0.0835238734250598	0.141086373407019
K30R,S89P	0.771995041162492	0.0495549909519297
K30R,S95P,R104T,Q126V	-0.0959342485569879	0.167110355306904
K30R,T35A,D66N,R104G	-0.392016730327469	0.109621191188005
K30R,V142A	0.709890152513346	0.110405483062964
K30R,Y87N	-0.510890553474845	0.22181089133615
K48E,A129P	-0.525894077647213	0.19164151409214
K48E,C93G,D127G	0.340481182971778	0.194199823409967
K48E,C93S,Q126H	0.560474793998078	0.253251846403231
K48E,E78G	-0.255699275625285	0.105656928645
K48E,E78G,R147S	0.388144590180693	0.122406527473537
K48E,F58L,K65I,V148G	0.457798394245786	0.196958783962537
K48E,F64S,S89P,L94P	0.101313767952892	0.107708481563066
K48E,G55M,E78G	0.253890105288536	0.127361159161561
K48E,H83D,I112V	-0.110449575861326	0.109365805040087
K48E,I125T,S158L	0.460993582286518	0.146157783110572
K48E,I96V,W103R,I109T	0.154652459934235	0.11860586581141
K48E,I96V,W103R,I109T,I116M	NA	NA
K48E,K65E,P69L,I112T,D127A,C138R,E145K,V148D	NA	NA
K48E,K65N,E98D	0.353173566668034	0.16378705986857
K48E,K74E,E122V,Y137D,N140S	0.381989643159179	0.169913161013431
K48E,L114F,Q130R	0.475284451880108	0.169599527897211
K48E,L120M	0.122803054089928	0.148358451112843
K48E,Q130R	-0.130478627319953	0.10439970654602
K48E,T51A,K146R	-0.048240222761267	0.0469168365073544
K48E,T91A	0.45519164586938	0.113119929161441
K48E,W103C,P128A,A129T,Q139H	-0.180006719937181	0.188042408679614
K48E,Y137D,N140S	-0.1061387199184	0.104471146875038
K48F,I112E,Q126E	0.144269753271054	0.113632520612929
K48I,L113H,N124S	-0.151671242988572	0.0693221881247055
K48M,F82Y,N124S,N140D	0.321122271977295	0.174897393397154
K48M,I116T,Y144C,S158P	1.14472944505457	0.22541529394893
K48M,N124S	0.29367972536579	0.137898580146619
K48Q,E122V	0.514024862018088	0.113684953985742
K48Q,K76G,Y137K	NA	NA
K48R,C93S,K101R	NA	NA
K48R,D66Y,E98G,A106Y,V142A	0.197172553104963	0.179441349279257
K48R,E122C	1.21651558463768	0.107754840069877
K48R,E78G,I125T,Q139P	-0.0906099619402725	0.133360755166986
K48R,E78G,N124D,I125T,Q139P	0.284756265039564	0.137473635743299
K48R,I116T,A156G	0.099960647678102	0.0413035950698622
K48R,I96T,D127G	NA	NA
K48R,I96V	1.80326235787074	0.110658933938515
K48R,K101E	1.22205743728662	0.114763135308568
K48R,K49E,I96T,D127G	-0.223590369990625	0.132137569212003
K48R,K59N,I96T,A150T	0.954735405228974	0.207437496573921
K48R,K59Y,F155S	0.247991138708191	0.165141121426213
K48R,N121K	0.506788823065419	0.100508258542169
K48R,N121M	1.0346699939018	0.100376407331159
K48R,P123V	0.253714775959742	0.108198297054625
K48R,P52L,D66E,K76R,P128F,Y134C,I136N,E145V	0.380771897677815	0.141559995592352
K48R,P88S,T135S	1.30033390049078	0.110818452577008
K48R,R104G	NA	NA
K48R,R61E,F77E,Q117R,I125N,Q126R,Q130P	0.0962843070985594	0.173219747423111
K48R,R61L,L113I,N140D	NA	NA
K48R,S95A,N124S	NA	NA
K48R,T91P,N140E,P157H	-0.169869177506367	0.0624375180906916
K48R,V86M,I107V	NA	NA
K48R,Y68H,K76E,F82S,E132S,V148A	0.1782867118899	0.157751825693977
K49E,C93Y	0.00759675601663987	0.115766147183558
K49E,E132K	0.176082426839137	0.10394497281411
K49E,F58L,K74R,P105A	0.204196977219179	0.186882281410152
K49E,F58L,P105A	0.0757840507476397	0.104805242130403
K49E,F58S,E99K	0.939324376371545	0.179290854797099
K49E,I112N,V148H	-0.58291086987565	0.222408627754599
K49E,I125K	0.0114590311163971	0.109595078288673
K49E,I136V,E145V	1.72431583222614	0.223545830989356
K49E,I96V	1.43282602658403	0.0809734908291276
K49E,K110R	0.50585546377795	0.048282882482392
K49E,M62T,K74R	0.484575480672737	0.335215495394845
K49E,P52L,P69S,Q117R,P123L,V142E	NA	NA
K49E,P69S,I107V,P123L,A133L,V142E	0.057627645792313	0.179885873082839
K49E,P69S,P123L,V142E	-0.19193006323649	0.0631031965361498
K49E,R141C	0.537265510444565	0.136192971486505
K49E,R147W	NA	NA
K49E,R149L	0.621841568967679	0.164728052202246
K49E,S158L	-0.413298285314447	0.280004730882096
K49E,W53R,F64L	1.1931031275296	0.158733157855192
K49I,C138Y	-0.148694819248463	0.109918059598973
K49I,E98G,A106G	1.34110291567786	0.115587232311265
K49I,L94P	1.47346373048987	0.163478526583534
K49I,N124K	NA	NA
K49I,S95P	-0.349469280074435	0.138133739539282
K49N,D67V	0.498987244770163	0.171466562197133
K49N,E145K,K146R	0.171512446413815	0.167277552339364
K49N,E78D,S89T,E98K,K154R	0.391711815129172	0.228101066673636
K49N,S89T	0.6703373713692	0.0859061592257995
K49Q,E78G,K146R	1.42102732427661	0.120359413530829
K49Q,N85D,P88H,I109V	0.147064391004153	0.11109121627434
K49R,E145G,R147W	0.000941853626663422	0.251881190325474
K49R,F77K,P123T,I136H	0.0393178803907935	0.159159591520122
K49R,I112T,Q139K	1.92794208208547	0.152849446925875
K49R,I136S	0.419968055962119	0.167022658657833
K49R,K110A,Y134C	1.04944288397193	0.110054916317266
K49R,K110E,V148I,F155S	0.244389683161049	0.0712425262103038
K49R,M62T,V92L,C93R,A156P	NA	NA
K49R,N124D	0.132171942617509	0.120527720745494
K49R,N140I	0.608023928401561	0.130381027071794
K49R,N85I,R141S,F155L	0.0100044342206522	0.127032345589466
K49R,R61W,D66G,T91A,L94P,N124S,C138W	NA	NA
K49R,R61W,T91A,N124S,C138W	0.217566598884007	0.107467069911358
K49R,Y87N,N140I	-0.197439562267118	0.0560509031342259
K59E,D66G,V142M	0.0450509729495676	0.125702192907151
K59E,E122G	NA	NA
K59E,F77L	0.466130071630247	0.147749833294125
K59E,G90W,L113P,E118G,A131V	0.234913224862378	0.108632756973997
K59E,I107T,D127A,R147G	0.212219296904694	0.147681665811057
K59E,I96V,Q117N,D127M	-0.19328573354144	0.144877995920954
K59E,K101E,E122G	0.114137398585533	0.15239539294763
K59E,K101R,A129C	0.148470165251455	0.113611259808879
K59E,K76P,V142Y	-0.261983588431924	0.127475708578745
K59E,L113P,E118G,A131V	-0.235258697985575	0.104677018014887
K59E,L60P,K154E	0.17608792886976	0.107477320950416
K59E,M62L,H83P,G90R,A106Y,P123G	0.338544226709174	0.106071509619583
K59E,M62V,K101E,L120P	NA	NA
K59E,M62V,L120P	0.000589200847543559	0.137435250817121
K59E,P80S,I107T,Q126E	0.732393991983295	0.113503692683195
K59E,P84T	0.121482197219021	0.116918757473624
K59E,Q126L	0.575235004620025	0.0991358772333092
K59F,F82H,L94P	0.00165535888598923	0.112661364320903
K59H,N85D,C93F	0.116766593886798	0.136349355321944
K59I,M62T,L94P,D102A,I116R	-0.30836027794651	0.131285821174512
K59L,P123T,Q130H	-0.0474254769712437	0.324386529287954
K59L,V148Q	0.0910070051204788	0.135016875755726
K59N,A106Y	-0.0908775553219408	0.18119683666393
K59N,C75R,I107K,A150Y	-0.116646014025532	0.0704350304384676
K59N,F64S,Q151H	0.315303618148987	0.132770126399448
K59N,F77L,I112T,Y137F	NA	NA
K59N,F77T,Q126P,Y134S	0.258677459047633	0.116078385906512
K59N,F82S,H83P	0.19381075673292	0.133375910360067
K59N,K110L	-0.14617663876139	0.197135451112006
K59N,K110V,P123L	-0.457743715582558	0.25520715514159
K59N,K65R,F82Y,E145G	-0.171187059880163	0.159213827485269
K59N,K74S,L120R	-0.0786229048461647	0.136174595693498
K59N,K76R,P157S	0.511465074066625	0.213471032458967
K59N,N121K	-0.289035445219275	0.291247578306447
K59N,Q111I,Q126W	0.844404306927429	0.106414156025286
K59N,T135A	0.892561335430802	0.115079746570946
K59N,V148H	NA	NA
K59R,C93S,N121S,P123Q	0.0197329166201079	0.167609573309483
K59R,E99G,I116T	1.05933292628987	0.177995310954625
K59R,F64L,I107N	-0.319587110152776	0.104350000517418
K59R,F64L,V142A	0.593144918321717	0.10947412284203
K59R,F64S,R104G,Y137H	-0.0360939688001337	0.173652399684844
K59R,F77I	NA	NA
K59R,H83N,A106S,E132Y	0.0591210455925661	0.229008619035316
K59R,I112F	-0.425653173844993	0.153331938798653
K59R,I112R	NA	NA
K59R,K74R,K146R,A152T,S158P	-0.0315315249779721	0.170892742737417
K59R,L63R,P72T	0.505953667409049	0.168743903636375
K59R,M62L,K74S,K101R,I109Q	-0.0427259202559046	0.151144493081727
K59R,M62T,I112V	0.344654668097877	0.0610956256311423
K59R,M62T,I112V,K153N	0.313860892755144	0.220932927824184
K59R,M62T,N85K,N121Y,D127G,K154R	0.119031282688205	0.187737306366945
K59R,Q117L	0.133123188199296	0.207091344282136
K59R,S70P,T108A,G115E,I136T	0.367346336596726	0.213300134307942
K59T,R141M	0.751956874096075	0.113740365706724
K59V,A131R,K153R	-0.0205220224445471	0.091494227146481
K59Y,L63R,L119F	0.301670276193324	0.196965563416763
K65E,C138R	1.64213464434044	0.0988980604828847
K65E,C138R,E145G	0.0535677097509313	0.146599367667445
K65E,C75E	0.209457475589674	0.116778133747263
K65E,C75R,Q151H	-0.362725158714018	0.117748603980803
K65E,D102V	0.322774985533753	0.0520121437586652
K65E,D66N,N85D	0.143703604741939	0.10847143872159
K65E,I112T	NA	NA
K65E,I112V,R141G,F155S	NA	NA
K65E,K101Q,I109N,P123L	0.00695571518766769	0.243555270041329
K65E,K76Y,Q117F	NA	NA
K65E,N140S	1.91060780792322	0.17770050072608
K65E,Q111S,D127I,E145V	1.44229866854057	0.162210124756133
K65E,T135S	1.49588137415698	0.0494861747605066
K65E,Y68H,I112V,C138R,E145G	-0.064978906122427	0.2097940358266
K65N,C75R,A131V	0.688874665258358	0.189199884978047
K65N,D67G	1.34058166022252	0.114078349068758
K65N,K146Q,Q151L	0.326217354275133	0.0765416545486764
K65N,K146R	1.55263245829408	0.104882639936721
K65P,I107L,I116V	1.36670368651392	0.0981343665823458
K65Q,P105L	0.0067970495267685	0.136341879416852
K65Q,P105L,Q126R	NA	NA
K65Q,T135S,K146M	0.0707261914076223	0.191648940281577
K65R,C93R,L114F,I116V	NA	NA
K65R,D67S,S71P,A106R	0.276805022642159	0.108100379622148
K65R,E78G,L97I,V148A	NA	NA
K65R,I96T	2.47324509154561	0.168038082715898
K65R,L97I	1.71241480490679	0.0878784100110744
K65R,W103R	-0.199179769121311	0.119566777227485
K65R,W103R,P123V	-0.00228410262338342	0.11622267452142
K65T,L114S,E122D	0.900907134684289	0.115632776168283
K65T,P72L,L94Q,L119F	0.433677932578432	0.197578701526947
K65T,S95P,Y137F	-0.087464434528823	0.0795294066060767
K74A,L119T,A156T	NA	NA
K74D,A106E	-0.00331457602665561	0.101397163155521
K74D,I112V,N124F	NA	NA
K74D,K76P,E99G,N140D	0.434515323602465	0.120066513886795
K74E,A106T,Y144H	-0.323506307923704	0.0750862010723474
K74E,C75F,L114S,L119H,T135S	-0.0949463541809929	0.245297486157114
K74E,D100Y	0.824917850358983	0.123325479709513
K74E,E118T	1.89548745589829	0.125628116892947
K74E,E78A,K146E	1.62486620294569	0.0969987887840619
K74E,E99G	1.97385266054919	0.128762517140107
K74E,K110E,E122V	-0.121164974928231	0.178126109464335
K74E,L114S	1.56502947570986	0.129907676863286
K74E,L94P	-0.142077858666034	NA
K74E,N85D,Y137H	-0.687648530071345	0.301708549938035
K74E,N85Y	-0.0273430370134387	0.11076421121536
K74E,N85Y,Q126K	NA	NA
K74E,P128T,K153E	NA	NA
K74E,P84L,V92A	0.146947047535131	0.113657913456056
K74E,Q117P	0.0698085631238824	0.09899696193241
K74E,R104K,I116V	1.16737266599811	0.137761158598293
K74E,Y144F	0.269965612383229	0.0918003698399806
K74F,E122L	-0.282422436605105	0.410015416945975
K74F,N121Q	1.0827284098547	0.102830868248883
K74I,K76C,T91Y,Q111H,C138N,K146R,S158P	NA	NA
K74I,N121F	1.29214939548976	0.126709112209899
K74L,L113V	1.39764719954384	0.0990945376271068
K74L,L119R	-0.344460265950044	0.206552686141398
K74L,L81V,N121T	2.11016173190132	0.210533769025029
K74L,V86M,S95D	0.0744864838307337	0.1093841580929
K74M,L81I,I112R	-0.315049516828917	0.142242811896729
K74M,Y134A	-0.61914316573554	0.13111047372044
K74N,L119N	0.0320999935709611	0.132009438607052
K74N,R104W	-0.0791966227975247	0.143833084670092
K74Q,A150V	1.97449184340612	0.116844888574725
K74Q,I107C	0.996199651614254	0.126742381735017
K74Q,I116K,A150Y	0.0562280367412892	0.165237024667091
K74Q,L113A,E122C,Q151R	-0.05550904228101	0.138114909461961
K74Q,S95P	-0.0610709733546385	0.162795539784786
K74R,F77P,I107N	-0.151298706742303	0.125199409491573
K74R,F82S,N121Y,A129T	0.27210987597719	0.17621482741023
K74R,H83L,S95P	-0.11109608466762	0.111567301756847
K74R,I107A,Q130T,R149G,K153Q	1.32025115500513	0.171285595544298
K74R,L113Q	0.27865104703399	0.103496784972472
K74R,L114S,E145G	0.0395354756403855	0.0991041732259171
K74R,L94P	-0.0891748880315758	0.0781382959770064
K74R,P84L	NA	NA
K74R,P84S	0.763078417407937	0.206314179090107
K74R,P88S,L97I	NA	NA
K74R,Q151L	0.115871394168217	0.119865025263153
K74R,S158P	0.509307109367211	0.103294989848602
K74R,V92M,I109V	0.536549639234273	0.171263359065329
K74S,R104G,N121I	1.25512167880758	0.133333043427348
K74S,T108N,K110Q,A129V,K146E	-0.0875251717114813	0.130444662473291
K74T,A131T	0.630981255364753	0.172276411603296
K74T,H83P,D127N	-0.014725176153045	0.136019500841554
K74T,Q130K	-0.0558438577484009	0.164437782389066
K74V,C93Y,L114K	-0.136996400275028	0.125983001894943
K74V,T108R	1.22193052119617	0.0964200750065128
K74W,W103R,L119E,E122G,E132G,K153H	0.903926053105572	0.127189573547195
K74W,W103R,L119E,K153H	-0.292039138558441	0.0983729508153875
K76D,I107V	NA	NA
K76D,Q117R,Q126M	1.56148077143794	0.113724552811359
K76E,D102E,W103C,E132G	0.433358771672223	0.189105295665867
K76E,E122G	-0.115399748543615	0.121287702240477
K76E,E122G,R147G	0.160971213278639	0.167290443020768
K76E,F82L,W103I,V142D	NA	NA
K76E,N121S	1.04078450040523	0.102651055648374
K76E,N124V	0.132236025788237	0.141576562407354
K76E,P79S,N124S,Q151R	0.0429221677871037	0.114770263988494
K76E,V86M,Y87N	0.374527727068341	0.17377971655832
K76H,A133I	0.484714263789571	0.100355266329285
K76H,L81I,E99G,V148R	-0.0926892371149324	0.114886832780719
K76H,P88T,E118A	0.0490164909043576	0.153243354542549
K76H,R104G,T108A,E143K	0.417388517611355	0.287766782188708
K76I,V142D,R149L,A150E,A156C	0.591580437918961	0.181380970321816
K76L,D100G	0.792647979114681	0.100063824063819
K76L,K146E	1.52304169205503	0.115085085646462
K76L,L113T	NA	NA
K76L,L81I,P128R	1.35326923218551	0.131466502671104
K76L,T91A,L113P	2.02948978971793	0.213870885997223
K76M,A133P	0.107850186406822	0.156250781817353
K76M,E145G	-0.561476982188708	0.212986217578158
K76N,E145G	0.151819845391578	0.15321253419581
K76N,I109S,N124K	1.79358008889928	0.178209576258563
K76N,I109T	NA	NA
K76N,L120Q,A156D	-0.189890740868477	0.128138593720961
K76N,Q111H	2.66148620501963	0.131047935308997
K76N,R104N	-0.143045948139158	0.10936707206744
K76N,Y87H	-0.186138397071213	0.115884767206798
K76Q,A106I,K153R	NA	NA
K76Q,A156G	NA	NA
K76Q,I112K	1.29534064388056	0.134308783811051
K76Q,L113P	-0.248829167748289	0.126299144422107
K76Q,L81I,C93S,E99G,V148R	0.36693683875972	0.191347765450295
K76Q,T108F	-0.00724708752509943	0.119790818370466
K76R,A156T	1.12822847815631	0.105543874467192
K76R,D100G,D102G,N124S,P128S	NA	NA
K76R,E132K	0.878731467065976	0.182989336128808
K76R,E78G,F82L,A106V	-0.0710237511061765	0.105997885134341
K76R,E99G	1.92290306253858	0.107530243699039
K76R,G90E	0.199639379134763	0.123230107436047
K76R,I109N,L120R	0.0546381877282521	0.106686853852479
K76R,L81I,P123C	NA	NA
K76R,P80S,E132G	0.946300133386788	0.181115515628406
K76R,S89P	0.838507767864999	0.18535755598814
K76R,S95F,Q117L,Q126L,T135A	1.002371520089	0.218047068661141
K76R,T135W,I136V	0.666320756542082	0.28446379117614
K76S,L81I	0.651738228705095	0.108523373222507
K76S,L81I,P123C	0.387864705513536	0.130570249922235
K76S,R141G,R149Q	0.964283491347573	0.0993477950337782
K76T,A106T,L114V	0.400532280276441	0.179226319664616
K76T,C93S	-0.0826659210261353	0.129121219335056
K76T,L119A	0.396888981911571	0.138772637500492
K76T,Y144M	0.00994859723463545	0.114471171812135
K76T,Y144M,K146I,P157H	0.451478846499647	0.231263822522957
K76Y,N121A,S158P	0.489475733092594	0.102041195054353
L113A,N140G	-0.00438556297212529	0.0995208778061631
L113C,E122V	NA	NA
L113H,N124S,K153E	0.773110188172048	0.219195476856791
L113N,N124K,D127G,Y134H	0.287424888752689	0.157555533747154
L113P,K146E	-0.042137172839259	0.104105310025129
L113P,L114W,E122S	NA	NA
L113P,N124I	NA	NA
L113P,V142A	-0.101297859990468	0.130566451598799
L113P,Y144C	-0.235784167193879	0.107899042429067
L113Q,N140T	NA	NA
L113S,T135P	0.622946950001206	0.172587145736094
L113V,Y137H	-0.290761051893071	0.204447870719555
L114F,A133D,P157L	-0.113810087072182	0.181007063073443
L114F,Q130R,A133D,P157L	0.143689834562161	0.161560383637603
L114F,V142T	-0.0209708652746872	0.130543093114221
L114H,R141G	0.118198031673509	0.128884923936297
L114I,N124D	-0.111262404735772	0.0917546583116471
L114K,A150S	0.420194586885858	0.0615617126933376
L114M,K153E	0.99079446713797	0.114398302279433
L114Q,A133T,C138R,E143T	1.21412582031715	0.200734868756325
L114Q,D127G	0.634430342962086	0.099734059968704
L114R,N121G	NA	NA
L114S,I136T,Y144Q	0.924403449311671	0.134258810919875
L114S,N124R,E143V	0.309230106835425	0.188468451428785
L114S,N124S,E143V	0.287648119812339	0.116510750182056
L114S,Q139F	0.913203251319007	0.12048650582088
L114T,K154R	0.79748473144186	0.138000755556116
L114V,K154R	NA	NA
L119G,V148P	-0.0605701834828057	0.0710370147432662
L119P,K146E	-0.0637359567551484	0.118139813332963
L119P,Y134H	-0.137237362124535	0.209641044900295
L119R,T135M	0.0291294756642967	0.230858292836885
L119V,D127G	-0.0691668786753943	0.121899891790335
L119V,E132S	0.233771268207021	0.0994825747218708
L119V,Q139P	-0.128271387137825	0.0706410672583445
L120I,R141S	NA	NA
L120P,C138S	0.539279165049882	0.199582049953859
L120P,Q126P	-0.147819431392511	0.205678066104824
L120P,T135A,E143K	NA	NA
L120R,A131V,V142G,F155Y	1.21548814932021	0.148202875166917
L120V,T135S	NA	NA
L38F,A129Q	-0.0616251257317937	0.107038943415935
L38F,P84S	0.336924167663979	0.119437076803476
L38F,R61L,L113I	-0.0722327915423089	0.108084196718559
L38F,S70P,V86A	NA	NA
L38H,I109C	0.2511727297926	0.134189662292597
L38H,I136N	0.0665773296124371	0.105527992933223
L38H,L119R	-0.0914373492288774	0.108337753705557
L38I,I107W,I112T,R141M,A156T	NA	NA
L38I,K59E,Q117H,E118K	-0.217051979970279	0.103372057599255
L38I,N121S	0.551711455503052	0.101190567712726
L38I,P73S	0.0421350179897499	0.0930415817650882
L38I,R104K	0.0231490512674228	0.120817180297398
L38I,S70T,K101E,V142A,Y144C	0.75798252622599	0.217336375672961
L38I,S70T,S89P	0.905508976394007	0.114475659788556
L38N,V142F	-0.476310888745262	0.154538955534295
L38P,E78I,L119H,A131V	-0.0559411560624153	0.178436655818343
L38P,F58D,R141T	-0.208011308935521	0.205941373988932
L38P,F58I,F155L	-0.163418219818761	0.121811678095971
L38P,F58I,N85I,F155L	0.937575321122469	0.203405205092558
L38P,F64L	0.346765406480759	0.17596767452467
L38P,F82K	-0.119883723061248	0.109242660811579
L38P,F82L	NA	NA
L38P,I109R	-0.0571872192951867	0.107036308224045
L38P,K110Y	-0.0785257792077743	0.168065475019022
L38P,K49E	0.385799074126637	0.135796379853061
L38P,K59R,A156T	0.676215577247492	0.114476777401375
L38P,K59R,M62T,D66G,N85K,N121Y,D127G,K154R	-0.128412209614292	0.240265605999706
L38P,K74R,I107T	0.126343486680298	0.122757307153414
L38P,L81I,E122L	-0.150141040342338	0.153943839926423
L38P,M62V	0.11072772641399	0.11764791347855
L38P,N40S	0.100865577490495	0.103519401662915
L38P,P73R,P123E,S158L	-0.238296460631151	0.114769050364879
L38P,P79R,Q139V	0.409279703686373	0.099221916024327
L38P,Q151R	NA	NA
L38P,Q151R,P157L	0.74591871397665	0.161025505977059
L38P,R141I	0.0601126830786323	0.073440581225571
L38P,R61Q,N121L,R141S,R149L	-0.107995266396639	0.126358081186377
L38P,T108A,P128S,T135A,V148I	0.414225942242326	0.206649309868146
L38P,T108A,V148I	0.253454686439785	0.185704894836633
L38P,W103G,A133S,V142A,V148D	0.376592044133456	0.178304082071302
L38P,W103G,V142A	-0.0841739975048002	0.121149909266651
L38P,W103G,V142A,E145V	0.314808147774447	0.105722390982684
L38P,W103S,E122I	-0.385174028794034	0.142054392763745
L38P,W41C,Q151R	0.167692514575127	0.0988844150176264
L38P,W53R	-0.0223266559195685	0.117007709649104
L57D,C75S,P128I	NA	NA
L57F,V142E	0.977995747342846	0.163271114398488
L57I,D66G	-0.0505194246083617	0.129904679691756
L57M,F77E,T135M,E145N,K153E	0.0523324617319094	0.119558566687431
L57M,S89L,L119P	NA	NA
L57M,Y87C,E122G,P157S	0.431344602992126	0.161951633895672
L57M,Y87C,P157S	0.238578481424029	0.110753626918314
L57Q,K59R	-0.0617522645417442	0.115340129541131
L57R,C75N	0.267817512664758	0.116883193881683
L57S,E122D	0.324776381824543	0.165898317051287
L57S,E143G,V148A	NA	NA
L57S,M62L,C93S	0.180246838883491	0.126900354561926
L57S,P80S,R104G,Q117P,R141G	0.239571106960599	0.169448683562217
L57S,Q117P,R141G	-0.0470438141593449	0.101677740355048
L57S,R141S	1.26388662995837	0.135308148166788
L57S,T91P,R104G,V148M	-0.088494498064763	0.100386972631587
L57V,D66V,K146R	-0.144275232094948	0.106076584987792
L60D,E118R	-0.0460080790197005	0.109007486260516
L60E,N124W	-0.0210934081292677	0.18341361484117
L60G,L63P,C75G,Q111H,N121K,V142G	NA	NA
L60K,I96T,R141P	0.160385010585242	0.106186244651174
L60M,F64L,R141S	-0.218665726180314	0.154567339216301
L60M,K76T	2.55869684504837	0.1446387369166
L60P,E122K	-0.0911593211820445	0.0548600793040896
L60P,N124M	-0.314822830829784	0.10433518875044
L60P,P105A,I109T,Y134C	NA	NA
L60P,P123Q	0.222403372875325	0.125299675121257
L60P,P69M,Y134A	-0.495120461573506	0.304341443798787
L60P,S95P,L120I	0.215564794334168	0.12824201242174
L60Q,C138R	0.675953279140932	0.198260893687411
L60Q,E122P	-0.11098268831061	0.114723209718584
L60Q,E122S,Q126R	0.0931245755803149	0.106736010198291
L60Q,F155S	-0.21649956512456	0.104728298365085
L60Q,F64Y	NA	NA
L60Q,F77S,N121A,V148I	-0.154342940842917	0.0868259170739761
L60Q,I109T,D127A	0.311650576967336	0.134908842139167
L60Q,I112V,E118K,I125T	0.164293845442224	0.112562234780097
L60Q,K110R	NA	NA
L60Q,L63P,I136T	0.377534483260351	0.231931757241712
L60Q,R141N	NA	NA
L60R,D67T,F82A,E118M	0.0513145248624198	0.193054586640976
L60R,F155V	-0.00635570531536413	0.0602996478635461
L60R,G115V,K146P	NA	NA
L60S,K74H,E122R	0.0619614824118854	0.186223602585988
L60S,W103P,D127V	0.247093512435195	0.104733589204223
L60T,E99G	NA	NA
L60T,Q111R	0.219900050344331	0.127748904343943
L60W,A150I	-0.388840628716595	0.176288301502138
L60W,N121T	-0.137215470487553	0.131857677497464
L63A,D67A,L119G	0.026017666526184	0.10291146038685
L63F,C75V,R104W	0.0609135728727685	0.0621786533777954
L63F,F82L,K146R,V148D	1.57576025970349	0.165843033446403
L63F,K65R	1.80463481681288	0.169994402661953
L63F,S70F	1.23536019849718	0.117625244234593
L63F,Y137H	-0.40542620658805	0.210140237050058
L63G,D67A,K74A	NA	NA
L63H,C75R,I109N	0.0804282883769277	0.184768670351875
L63H,F77L,L97S,Y137F	-0.244882742095859	0.100881941876683
L63H,G90E	NA	NA
L63H,I116V,E143K,Y144H,A156T	NA	NA
L63H,R141S	0.28640217701446	0.100665237285
L63I,A152T	NA	NA
L63I,D67A	-0.191406005117863	0.142959009458791
L63I,N140D	1.21860381651152	0.226781849215539
L63N,D67A,F77Y,Q111R	-0.155341137066947	0.171790297099252
L63N,D67A,S70P,L119T	-0.106338638943083	0.151205727008226
L63N,D67A,S71L,C138R	NA	NA
L63N,D67A,S71L,F82T,E122T	-0.356641415185598	0.111310610880249
L63N,D67A,S71L,F82T,E122T,D127G	NA	NA
L63P,C75K,K110E,P157S	NA	NA
L63P,D100G	-0.155065802392389	0.124606420865017
L63P,D67A,T91A,E122R	0.0135016841213631	0.113169851941511
L63P,E99G	0.169771101254074	0.0783768747316509
L63P,E99G,L114F	1.36435395947505	0.175014590463968
L63P,F64S	-0.0456321562670871	0.106623346241153
L63P,K101N,N121S,Y134C	0.110124301320796	0.12403626650727
L63P,K110N,I116T	0.207207678454602	0.203064620324705
L63P,K74H,W103V,E122K,R149P	NA	NA
L63P,K74L	0.000203118656174056	0.124541748689178
L63P,K74N,C75S,N140D	-0.216921496592035	0.171432496460345
L63P,K76R,F82L,A131E	0.870809432948079	0.225998422096962
L63P,L120S,Y134L	-0.275046884345019	0.135558730964723
L63P,Q111P	0.123387939775916	0.122176855562303
L63P,S70P	0.441861203046358	0.237414552391829
L63P,S70P,C138S	1.08808602116321	0.142460798596238
L63P,S95P,E122G,D127G	-0.134179067631067	0.119534120236011
L63P,V86G,A133V	0.0474356531556854	0.172456740852317
L63P,V86M,K101N,N121S,N124K,Y134C,T135A	0.0531268164993895	0.161993437519484
L63P,V92A,A106T	-0.139758976613629	0.122290120244442
L63P,V92A,E145K	-0.133905293733003	0.104071921732472
L63Q,D67A,I109F,N121D,Q130T,Y134C	0.864947153361573	0.140622439462174
L63R,D67A	0.625691447019687	0.126935977284995
L63R,D67A,R104A	0.0302699486147965	0.332640246056534
L63S,F77S,I112P	NA	NA
L63T,D67A	0.930974354367487	0.11387463366077
L63V,D67A,P73S,E99G,I116V,Y137C	-0.329858125435427	0.175580391139594
L63V,I96V,W103R,L120P,I125T	-0.366858744457214	0.260889108781679
L6F,A15V,D127N	-0.0226753199264362	0.138018461712558
L6F,D19G,N31D,P52L,Y68H	0.307956527987754	0.135271711332682
L6F,D67S,E99G,A133P,Y137F	-0.082930047335639	0.11204411004824
L6F,E42G,F58S,L113V	0.30836787460247	0.117414077813542
L6F,E42G,L113V	0.165172758988148	0.114713091600485
L6F,H20R,Y68L,K146R,A152P	0.0541408709984964	0.128768432898805
L6F,L94R,K110R	0.173348974044317	0.114529564733232
L6F,T108A	-0.211125926790789	0.181244057488979
L6H,D66G	NA	NA
L6H,D66G,L97S,Q139R	0.252307172664501	0.117202623708555
L6H,E42K,C43R,I96T,F155S	0.752652137156321	0.137518462400068
L6H,E42K,L97S,F155S	0.114962150538542	0.106598340184621
L6H,F22L,N31T,W41K,M62F,K74I,V92Q,A131E,K154T	0.135750696066201	0.122979372320309
L6H,I107V,R147S	-0.126667525586018	0.145836234857729
L6H,L9P,F64L	0.044513073110148	0.20168885198145
L6H,M36T	0.698915083424121	0.181666583898903
L6H,Q139L	-0.0660309220795813	0.136440296760731
L6H,Q139L,S158L	1.05518052094185	0.159815084435916
L6H,S158L	NA	NA
L6H,S71L,Q130R	-0.280437699303572	0.203797570926636
L6H,S89W,A131V	-0.0508169636142184	0.0846162029827789
L6H,T29A,W41R,L97S,E122K,V148A,F155S	0.416446715601115	0.120896958471443
L6I,R61Q,D100G	0.605419606285957	0.10258749618801
L6P,D66C,H83L,N85D,N121F,Q130L	0.00805163547548621	0.125508297062744
L6P,H20R,N121D,V142F,V148A	0.638997032223234	0.164286007776172
L6P,K110I	-0.181975840108013	0.13086785134652
L6P,K14L,K48I,M62Q,K74T,Q111P,I136V,N140F,P157F	-0.147878974679904	0.115915776951329
L6P,K14R,D33N,N140D,V142A	0.178859489914791	0.0705119026015068
L6P,K48I,M62Q,K74T,Q111P,I136V,N140F	0.108894479120349	0.173295453100331
L6P,K59E,F77L	0.607478576729418	0.128576221334991
L6P,K59R,P72S,Q130L	0.140440533252044	0.101444344125901
L6P,L113T	0.146176893378654	0.118479035993883
L6P,L114S	0.219720351389759	0.124850621749799
L6P,L114S,E118G,V142E	0.562204419539227	0.170450955737813
L6P,L60I,D66G	0.307602190236472	0.119148764899292
L6P,M62Q,K74T,Q111P,I136V	0.272203296156885	0.196907623547765
L6P,N85S,T91A,P105T	0.123432897918389	0.118367892408078
L6P,P88H	-0.146172503973085	0.0697983360836423
L6P,S7C,M39T,Q139R,A150N	NA	NA
L6P,S7C,Q139R	0.581339218030136	0.105581610883046
L6R,C93R,R104G	-0.0216079682556751	0.132416800636022
L6R,N31S,L63M,D67A,S71P,N121D	0.771923642947437	0.199871509695417
L6R,P21Q,K30R,N31R,S71P,S89P,T108N	0.10853000432682	0.11222235041762
L6R,P21Q,N31R,L63M,D67A,S71P,T108N	-0.162773303660727	0.179346036278393
L6R,R104G,Q139L	0.128341556246601	0.219063850255772
L6S,V27A,I45T,A106L	NA	NA
L6V,K18E	NA	NA
L6V,K18E,F82S,L97K,I109S,E122R	0.142957954707931	0.199432811409416
L81D,N121P	0.180688407378223	0.122569242983772
L81D,R104C	-0.00803784547869757	0.121579206140031
L81H,R141F	0.18471921041711	0.126017303827366
L81I,N124I,K153M	0.0707861512314742	0.0878241335333611
L81I,Q117T	0.110106150503174	0.165696987371899
L81I,W103R	-0.0666272648244856	0.110755024962059
L81K,V142K	0.0780558126321337	0.119221281747193
L81N,D127I	-0.0630735491109964	0.150675169345265
L81N,I112S	-0.135133802954609	0.128090506518878
L81N,N85D	-0.0876206671125657	0.11080476152601
L81P,N85H,T108L,L114I,N121I,C138V	-0.0932612665500402	0.115721258945575
L81R,L119F	-0.239874326756439	0.146681807371997
L81S,C93R,Y134H	NA	NA
L81S,L114Q,A133T,E143T	-0.17484271660354	0.167606346913671
L81S,L120R,I136S,R147G,A152W	-0.220814835669101	0.186720632612576
L81S,P105Q	0.101909348763917	0.112871237630538
L81S,P105T	0.100334683328676	0.142755448700178
L81S,Q111P	-0.0949357175524707	0.140983304750508
L81S,R104G,Y134N,A150V	8.12660313670455e-05	0.120367572767715
L81S,S95P	0.081986341301507	0.0986701444581838
L81S,W103F,N121A	-0.357296497311505	0.113722068454032
L81T,E132G	-0.00888520253729978	0.192657688054689
L81T,L94M,E99G,P128D,Y134C	-0.0640142725516524	0.133642964237515
L81T,Y134A	-0.133945008458735	0.201707534718772
L94M,S158L	-0.794036826353478	0.334931033026048
L94P,G115R	0.253800252186154	0.192145109397857
L94P,I96T	NA	NA
L94P,K110N,Q117H	-0.165736223106748	0.0771721504303179
L94P,K110S	-0.0316273344201731	0.131323838812607
L94P,K154T	-0.119857549151869	0.0481875057428559
L94P,L97S	0.831878245455471	0.188416591432551
L94P,Q117R,N124S	-0.142954618827412	0.130625158026038
L94P,T135P	2.3099509970437	0.135943404627502
L94Q,D100G,R104G,D127G	-0.171251377658118	0.0996469699500681
L94Q,N124D,K154R	-0.00186496306379747	0.138812890772196
L94V,R141I	1.94690872546182	0.174571509718729
L97F,C138W,P157L	0.203799646514208	0.107333234573123
L97F,P105S	0.366605429070198	0.139902708099309
L97F,P105S,Y134C	NA	NA
L97F,Q111A	0.048188796312363	0.16219552732027
L97F,Q117N,Y134C	NA	NA
L97I,E98K,I116T	2.21020514798446	0.170162005858513
L97I,K110R,I112T,L119H	0.0580045581889793	0.052669840908109
L97I,K110R,I112T,L119H,C138Y	NA	NA
L97R,E132G	NA	NA
L97S,A106T,E143K	0.786826762674124	0.101174995639228
L97S,K110R,N121S,T135A	0.297209345573361	0.174817156509136
L97S,K110R,T135A,R141G	NA	NA
L97S,N121D	0.761946490399581	0.193478408092776
L97S,T108A	-0.463851450085148	0.156159968184083
L97S,T108I	0.0694989555887368	0.136054550532684
L9F,A10T,W103C	-0.180480643461779	0.112234951593492
L9F,K48E,N85S	-0.057062593990368	0.0975244603478288
L9F,L63F,Y137H	NA	NA
L9F,M62V,V86A,I107N,K146N	0.356722799572667	0.0990031586791491
L9F,Y144D	-0.0956122724344747	0.0998640867707154
L9H,D19E,G34V,G47K,F77Q,N85I,L120R,R147S	-0.564643357021658	0.245911579053713
L9H,D67N,L120P,Y134H	NA	NA
L9H,F22L,A106T,T108A	-0.00679667000497447	0.12185347377778
L9H,G115V	0.041621725336956	0.10890013138341
L9H,L63P,R104M	NA	NA
L9H,N40D,C43R,N85S,K153E	-0.133669643419996	0.0574207625876689
L9H,P32S,G55R,P72L	-0.151150850520544	0.116005680919495
L9H,T29A,K74R,P84Q,E99G	-0.0539220359677464	0.0570339511602589
L9I,Q11L,V92E,T108S,D127V	-0.0981228628114329	0.172572325436112
L9I,V25E,N31S,V86M,I107A,A131P	-0.0723481683964566	0.113969010469255
L9P,A106V	0.111527001074916	0.134915021727785
L9P,A106V,Q130P	0.112435449909332	0.196917780253135
L9P,A10V,G34S,I112V,N121A	-0.0886049296910161	0.144701993252643
L9P,A129T,N140S	1.018613641306	0.206263477694629
L9P,E12G,V27A,P80L,D100G	-0.0398606398081079	0.244282328761031
L9P,E54G	-0.12382831887952	0.109515498072938
L9P,F22S,E54G,M62T	0.774354514718158	0.134636426385266
L9P,F24L,P80G,I112T,T135S	-0.140536344463632	0.100882151741666
L9P,F58R,M62R,P73N,F82L	-0.0602462151959903	0.0653589221131098
L9P,F58S	-0.0677245073553487	0.108593179230626
L9P,F64S,P79A,L120C	-0.242839411890878	0.172573091408168
L9P,G23C,L63P,S70F,E99K,P123T	0.0150247184349401	0.111138941720528
L9P,I125L	-0.117373045727655	0.119521399299098
L9P,I45T,R141G,V142G	-0.127301991505787	0.112563393602067
L9P,K14I,N37D,D102G	0.239481529030375	0.135104798226122
L9P,K14R,L94V	-0.176064227385572	0.108401281419927
L9P,K18E,L38I,I112V,N140S	0.0167335365089447	0.182692927812263
L9P,K18E,M36T,L38I,I112V,N140S	NA	NA
L9P,K30R,R61L	0.264009066271275	0.373127562317038
L9P,K49E,F58L,D67G,K74E,K101E	0.307308475158878	0.252134385946599
L9P,K59E,P84Q,Y87H,P123S	0.316073777143362	0.195985043702197
L9P,K59I,K65E,L94Q	2.5178465463739	0.184646710158994
L9P,K59N,P73Y	NA	NA
L9P,K74R,I109Q	0.221659079245431	0.129040317288811
L9P,K76N,P105Q,L114F,E122S,V148M	0.233266036618944	0.117803439599229
L9P,K76P,Q126K	0.191782106729997	0.051422877667303
L9P,L38P	NA	NA
L9P,L60Q,E122S	-0.0223309062064659	0.109015996136952
L9P,L94R	0.0926898060101767	0.116950632896091
L9P,N37D,L94R	0.323133699045614	0.164875887249878
L9P,P32S,C43Y,F64S,E118V	0.121654522216401	0.184679797917841
L9P,P32S,F64S,E118V	-0.0368706894922763	0.0712654785592182
L9P,P46S,I125T	0.04995270396053	0.0528820928006586
L9P,P46S,K49E,I125T,R147G	0.0727457836784132	0.221673992237075
L9P,Q126H,N140D	0.119958122385041	0.202528684789255
L9P,R17G,A133S,C138Y	0.135988102605671	0.187280717134244
L9P,T29S,N37D,M62V,P73L,G90W,I107T,L119F,N140S	-0.152118348328881	0.118802040115863
L9P,T51A,S71L,F77S	-0.254649080646299	0.142850023575126
L9P,V25A,K59N	-0.333998324983587	0.137491398234274
L9P,V27A,T29S,D100G	0.0247099162881592	0.119516670976854
L9P,V86A,D100G	NA	NA
L9P,W16M,L38H,Y87H	0.385865010382956	0.141930574597398
L9P,W53L,L57S	NA	NA
L9P,Y87N	1.56599451070912	0.196750002609831
L9V,G115V	-0.0363580534294977	0.116139803398439
M1I,A15V,F82Y,L120K	-0.129554492138221	0.12710573073955
M1I,D19G,K30R,K65R	-0.325910282236827	0.0965423325197768
M1I,D33G,F58V,E99V	0.491631632496085	0.124791119218085
M1I,E42K,L114S,E122Q	0.0894955544664194	0.140568685229319
M1I,F22L,K30R,I116V,Q139K	0.210074433054119	0.109099655004713
M1I,G3R,G56D	0.0844567237672525	0.11118012373764
M1I,G90R,D100G,F155S	0.132344091664868	0.17418847422648
M1I,I107F,A150R,S158P	0.186786591976589	0.125436642671118
M1I,I45T,D67V,I107F,A150R,S158P	-0.177247811670627	0.167081008268915
M1I,K18E,I107T,K110E	-0.157618155293869	0.206966758696163
M1I,K74E,F82T,I112L,Q126H,Y134H	-0.166902317130099	0.103015454145798
M1I,K74R	-0.693116514397396	0.263803982936825
M1I,L38F	0.292176813919777	0.0989984624363546
M1I,S2P,R13G,V25M,A44G,S89P,N121S,E132G	0.403443648451931	0.14749689754556
M1I,S2P,R13G,W16G,V25M,A44G,K49R,S89P,E132G,E145G	0.124377484031947	0.180743088945518
M1I,W53R,P73Q,P157L	0.00867501319539567	0.0964120886927125
M1L,F22S,M62T,S70L,L119P,I136T	0.317985359329319	0.183133502473533
M1L,F58L	-0.090804735767019	0.116845692728284
M1L,L6H,V25A,T51S,L119R	0.650491653331476	0.195301500125061
M1L,M62T,S70L,I136T	-0.28226102656373	0.119417274062294
M1R,F82S,I107V,Q130R,I136T	0.0770040936608398	0.184459999714773
M1R,I107V	0.128036474016993	0.0895736477053439
M1R,P46L,I96T,I107V	0.18435395139396	0.185108184923309
M1T,I4T,L6V,A44S	0.107064646781359	0.109204346886594
M1T,I4T,L6V,A44S,D102G,T135K	0.236292894688623	0.180782920250753
M1T,K48Q,A133S	0.000920829778921719	0.117957193029165
M1V,E42G,L60Q,Q126T	0.515780468160104	0.165400011725772
M36I,K74G,L119R,N124D	-0.0576481027443588	0.112841220942816
M36I,L94P	-0.177114072208341	0.124774268842121
M36I,P52Q	0.239406527272526	0.114239713736785
M36K,N140S	0.160239677357792	0.0427757624241524
M36K,N85Y,C138R	0.190669804908865	0.202300905934189
M36K,P72R,K76R,Q111R,Y137F,Q139G	-0.310946999851884	0.194188232385395
M36L,K110E,L120P,N124D,K146R	0.071526037297318	0.106743573414325
M36N,C43S,E122L	0.0852604513502323	0.129372663164454
M36N,E54G,V148A	-0.432773022082072	0.139307215177723
M36P,D67L,L120R,C138R	-0.186866492284418	0.137154427585311
M36T,D66G	0.0751444056234959	0.0997626721369846
M36T,E143K	-0.0539908508503736	0.115694206518661
M36T,F82L	-0.0117227994102899	0.0808488690475046
M36T,G47R,G115A	NA	NA
M36T,G50M,M62R,P72L,S95Q,L114G,A129L	-0.24012939521823	0.10771285110256
M36T,K48R,P105L	0.00788317471275236	0.0381064630389897
M36T,K48R,Y68S,P105L,E122K	-0.377363106154279	0.227995616507266
M36T,K65E,S70C	-0.0617590549358907	0.158569899403238
M36T,L63H,E99G,R141G	NA	NA
M36T,L63S,D67A,A106C,Q126L,A150G	0.0252401307417691	0.123475070736161
M36T,L94P,L113H,Q139H	0.332552701587926	0.265839382674407
M36T,N85D,I109N	-0.0605622972940685	0.115276739756492
M36V,D66N	0.161309307186812	0.12359909250517
M36V,E42G,I112V,L113P	NA	NA
M36V,E98G,W103R	-0.371955903440333	0.105957209947145
M36V,E98V,E122G	0.3974965113181	0.117371562005774
M36V,E99G	0.420580293247024	0.0988036375723848
M36V,F64L,Y68H	-0.371259235064726	0.115085321080882
M36V,G47R,E54G,L114T,E118D	0.252305272048618	0.105819194278124
M36V,K101R	1.6831944400689	0.162855115666389
M36V,K48Q,K146R	-0.026199554168844	0.0823687674624664
M36V,K76E,C93S,A152V	-0.125541535589717	0.0341593556861985
M36V,L38P	-0.0791782474880796	0.123606141259017
M36V,L57E,K74R,N121K,Q126K,V142A	1.9983672936571	0.158080314935659
M36V,L60P,K74E,R104G	0.140416395151527	0.118446384919851
M36V,L60P,R104G	0.414284737187995	0.111915000377185
M36V,P128S,T135A	0.0100892666784914	0.111782284659004
M36V,P69N	-0.153849577272916	0.12911909646445
M36V,P69S	0.261778823797994	0.10507159057115
M36V,P69S,Q126P	0.100446502770671	0.106021609249693
M36V,Q130R,F155I	-0.133847862426524	0.107282744354504
M36V,R104G	-0.436969986332645	0.0991570262285431
M36V,S71P,C93G,K110E,Q111R,R147G	-0.271850898587511	0.193830459806887
M36V,S71P,C93G,R147G	-0.217012271406909	0.121446273998143
M36V,V148I	0.0972276829410291	0.1307233851919
M36V,W53C,E78G,A150V	-0.0407154710388598	0.11011970778565
M36W,L60P,L113H	-0.151965541546919	0.0987632514996541
M39I,A106T,E122C,R141G	0.139710175771472	0.159635022830965
M39I,I45V,A129V,K153E	-0.0880608645034377	0.038651983914494
M39I,I45V,A129V,K153E,A156T	0.158819253334369	0.12557645755347
M39I,L60P,I107T	-0.114402150426048	0.117058665289511
M39K,I107T,E143C	0.0927693969374764	0.0908017492560321
M39K,R141S	-0.0512110814818834	0.105617045894226
M39L,A44T,R147G	0.369176140562134	0.160409185988574
M39L,D100G,Y137S	0.746926028680143	0.192012016573063
M39L,I112T,Q130R	1.35702504417366	0.102713569765998
M39L,I96V,I112T,E122G,Q130R,Y137C	-0.0976703791178108	0.217484141511605
M39L,K153M	0.388931180517801	0.125452243499952
M39L,K76P,Q111A,N121K	0.0675083715890923	0.142238965050405
M39L,L113S,P123G	0.0997948949060841	0.118392838627936
M39L,L120R,Q126D,I136S	0.211325899126081	0.172120943588389
M39L,S71G,N121S	1.12363864643587	0.100287828559751
M39L,V142A,K154E	0.348445232535766	0.115869012819487
M39S,C43W,A44F,K74L,Q126S	-0.104924530519487	0.111333423777114
M39T,F58L,K101R,K153M	0.511892760397044	0.193329654074585
M39T,K101E	0.687988812516565	0.100918024515066
M39T,K110R,I116M	2.49293509349293	0.173474196002892
M39T,K49E,S95T,E99K,P157T	-0.0552095909503443	0.107605102251182
M39T,M62V	0.0802056387659772	0.252651503829884
M39T,N40D,A44G,W53R	-0.055299019899796	0.0267382066309795
M39T,R61Y,I112T,E143L	0.188213964695038	0.15591094455669
M39T,T135A	0.57018373566545	0.0509007603113208
M39T,T91I,Q126E	0.899099782552871	0.084423879510923
M39V,D66S,R141A	0.113926290334249	0.102967042533686
M39V,E78A	0.724198340715438	0.141166653056427
M39V,F77N	NA	NA
M39V,F82S,Q130R	0.0636238543199855	0.10215473667419
M39V,K48T	0.231414434766648	0.101883402746558
M39V,K74S,R149N	0.634155640897404	0.14858287513848
M39V,P128L	-0.13793620089519	0.0430286578384976
M39V,S71L,S89T	0.863880668436035	0.178183432716081
M39V,S89T	1.46492752576956	0.176033433502943
M39V,S89T,I125T,A129P	NA	NA
M62A,E78T,E122S	0.838353086148727	0.116441518446448
M62A,F77I	-0.298594523890866	0.217081669086677
M62A,K74S	1.14219142603762	0.113844191537871
M62F,L120P	0.135570194512064	0.14951456305465
M62I,G90W,D127G	-0.185205824548301	0.110767125742422
M62I,I107T	0.54562488429193	0.118968235782412
M62I,I112V	0.81641884119418	0.077127297577399
M62I,K74M,V148A	0.304659443892136	0.160365537939843
M62I,K76R,C138R	1.51773066873294	0.285822351525349
M62I,S70K,N121V	0.901994190728153	0.11382174786294
M62K,D66G,S70P,K74R,R104K	0.0257943831938029	0.211767416449247
M62K,E78G,Q139H	-0.277703461527988	0.0929697646731328
M62K,E78G,T91I,S158L	-0.167266644552328	0.225944162968185
M62K,I116T,A133D	-0.0310559148699367	0.112734986368599
M62K,K74R	0.225269415716379	0.10769145154602
M62K,K76M,A131R,T135M	0.0552342131121092	0.219160943621009
M62K,K76M,L120E,T135M	-0.345738948035834	0.0813907281344499
M62K,L120E,Y134H,T135M	0.191420713677956	0.200428206436216
M62K,Q139H	0.148816317777038	0.19203113962968
M62L,D127G	0.3668786135762	0.156577507242721
M62L,P123R,A131P	-0.202440615488818	0.13159265204595
M62L,R104A,P123R,A131P	0.291386924031299	0.16673075430491
M62Q,I136V	NA	NA
M62Q,K74T,Q111P,I136V,N140I,P157F	0.220840624703946	0.175832006542446
M62Q,N121G	0.00499042759040384	0.198557354854612
M62T,A156V	NA	NA
M62T,D127G,R141G	-0.346951759718193	0.12671265082709
M62T,F77I,D127G,R141G,K146R	0.144476759526424	0.189598476198553
M62T,F77L,G90V,Y137F,K154R	0.0659809738744391	0.108343046488544
M62T,I107N	0.00712341336515857	0.135599611851631
M62T,I136S	0.150909913024337	0.113234124972837
M62T,I96T,D100G,E145A	0.771748498374539	0.235641925374863
M62T,K101R	0.0510694527069482	0.105499685230324
M62T,K74E,E122D,V142M	1.00983898949788	0.11288545946712
M62T,L63R,F82S,Q130R,I136T,A156T	1.14709873918395	0.192200519212902
M62T,L63R,F82S,Q130R,I136T,K153E	0.269234642584293	0.188965924138298
M62T,L94P,K110R	-0.131063177146079	0.124663798025613
M62T,L97S,D102Y,C138W	0.314065236955542	0.140474422348621
M62T,S70L,T135A,I136T	0.133694335365391	0.123666290551729
M62V,C138R	0.675371053091278	0.181400400169348
M62V,C75S,V86A,P88L,K110P	NA	NA
M62V,D127G	-0.0436393933846149	0.121701550036998
M62V,G90R,K110E,I112V	0.183671533748977	0.166895264273096
M62V,I109T,L113F,Y134H,S158P	0.166866563614425	0.120613482292665
M62V,I125T,C138R	0.261141320594513	0.167617674898617
M62V,K110E,I112V	0.536006421554561	0.123351013651488
M62V,K153M	0.60509115369237	0.0445864080804877
M62V,K74R,L113Q,D127G	0.358557231061025	0.159832231754007
M62V,K76R,E132K,K153M	0.37812326523276	0.097887837014569
M62V,L119V	0.224575253836802	0.0614475634679409
M62V,S71P,I107F	0.459342429528008	0.248713101888587
M62V,T135S	1.8414553134321	0.165442819416897
M62V,T91A,I109F	1.35634782898539	0.243271996018119
M62V,T91S	1.87419908832791	0.106346923056414
M62W,D102E	0.15401789863568	0.102729850824702
N121D,P123S,Y144C	0.0753283739831993	0.13234035167348
N121E,R141G	0.190478626781374	0.0708538437713875
N121F,R149Q	0.252962590166876	0.128693763077425
N121G,F155L	0.597847661584419	0.298941146943267
N121I,P157S	0.563703420093072	0.0995784221979902
N121L,A131T,Y137C	-0.111545336208064	0.189313479517941
N121S,R147K,K154R	1.49661490239475	0.12318323489719
N121T,E145R	0.727283765218458	0.117851306016982
N121Y,R147G	0.0547917871040904	0.0961346593165967
N124A,E145K	NA	NA
N124D,R141K	NA	NA
N124E,R141K	NA	NA
N124L,E143G	-0.081861597726822	0.100076931943163
N124L,Q139K	0.291904003837872	0.175509327866862
N124L,R149G	NA	NA
N124Q,A150W	0.05162659825843	0.102556605423234
N124S,K146R,S158A	1.41191391744266	0.170050491511752
N124S,S158A	0.542840725725129	0.161156666984989
N124Y,K153E	1.67868824690608	0.16252925722306
N140D,F155S	0.281388928948238	0.230299084450453
N140D,V148L	0.179119586600546	0.106376306080468
N140S,A152D	NA	NA
N31D,A44G,K110R,E143G	NA	NA
N31D,G90R,L94M	0.602479122400845	0.156565213301841
N31D,K74E,E99G	2.12389426032836	0.166022366854997
N31D,K76A,G115V,R147Y	0.0901315294093789	0.1330587161594
N31D,L119F,R147K	0.0674493840324673	0.0848507493899129
N31D,L38P	0.116942855096985	0.108789453396649
N31D,L97S	0.364643020759467	0.106190159518091
N31D,L97S,W103S	0.370946135244921	0.226531129187457
N31D,M36V,L38P,T51A	-0.0537018778878948	0.133864045751702
N31D,M39K,P72L	NA	NA
N31D,M39V,I96F	0.209871304655995	0.259638069413866
N31D,S70L	0.209754030617307	0.108529979855218
N31D,T51S,E132G	-0.117741969471657	0.191050891335564
N31D,V92E	0.59778718118203	0.172060486836053
N31D,W103R	0.1505404717754	0.114676918764364
N31F,C93G,R147E	-0.022489202072495	0.149155759784296
N31G,E54G,K74M,N121W,I125T,V142L	-0.0306588087750112	0.0795472533629829
N31G,I45V,E54G,K74M,N121W,I125T,V142L	0.315012050636368	0.2084142162457
N31H,G34S,Q139R	-0.0395423761029208	0.145032556168558
N31H,R61T,P73R,Y87D,P88H,E118L,E132G	NA	NA
N31I,D67N,K146N	2.11043933420558	0.112887534825769
N31I,E42G	-0.0723295670222744	0.11993342680734
N31I,E54D,E118G,C138S	0.0841202060374177	0.108425766236235
N31K,I116K,E118K	0.170290673511135	0.0616718372249119
N31K,I116M	1.02270243919514	0.100240327643146
N31K,Q111S,G115E	-0.442073668245529	0.192968018282967
N31K,R104N	0.0794609908080291	0.112881541086869
N31L,E118P,A133S,R141W	NA	NA
N31L,E78G	-0.0498312668039328	0.337279493715959
N31L,G47E	-0.29806329549731	0.142127379251734
N31M,R104Y	0.0133437242891493	0.125281028326947
N31Q,K74P,Q111H	0.132571851841074	0.111676699862869
N31R,K110D	0.0915476036602545	0.121742168208046
N31R,K76R	0.441444539935932	0.20970393125027
N31R,K76R,E99G	NA	NA
N31R,S70Y,L81F,Y134F,R149C	-0.2253902180856	0.14035183247676
N31R,T135A,K153E	0.104019607179471	0.201078353298202
N31S,A152V	-0.0716553913890639	0.364521323275587
N31S,A44D,F64L,P72L,C93W,I109V,E118G,Y134H,Q151R	0.49634066659034	0.217922700421975
N31S,D33G	0.336684373706208	0.123199033527941
N31S,E42G,A44T,R104W	0.129875036918719	0.101154451570607
N31S,E54G,K74M,N121W,I125T,V142L	-0.118459978467347	0.131738834625221
N31S,E78G,L114T,N124R	0.75091446892386	0.313725618605925
N31S,E98G	2.75406105211038	0.128805498314909
N31S,F82I,N121Q,V142A	0.150556169578243	0.114842865653398
N31S,F82I,N121Q,V142A,V148A	1.10770894502074	0.186031497969122
N31S,I45F,E54G,E78G	0.939767575269197	0.172279693715085
N31S,I96A,A150E	0.243844014600478	0.049165640391784
N31S,K101R	NA	NA
N31S,K59E,M62T	0.457711820907568	0.103500840098345
N31S,L114T,N124W	0.220613481621541	0.112459879443625
N31S,L38I,F58Y,Q111R	0.250381728820015	0.275243243269358
N31S,L63F,W103R	-0.0780936780444571	0.107100876804715
N31S,L97F	0.124361329451389	0.126375273458017
N31S,M62T,K154R	0.026783757710183	0.121008732973572
N31S,N40S,I125T,Y137F,C138Y	0.328774226284355	0.104167257803494
N31S,P52L	0.193138100564492	0.0755707328423697
N31S,P52L,N121I	0.811543507315559	0.172175684903169
N31S,P52L,Y137H,Y144H	-0.314708045203126	0.193300221906942
N31S,P79L,Y134H,R147S	0.0437134628646104	0.19756077265781
N31S,Q117R,Y134H,N140S,A152V	0.488813441288558	0.162699821112414
N31S,Q130R	2.01868074387527	0.170473564805937
N31S,Q139R	NA	NA
N31S,S158P	0.525797174925065	0.132587360741897
N31S,Y134H,A152V	-0.22715850416999	0.0734545044301675
N31T,E143G	NA	NA
N31T,F77R,N140V	NA	NA
N31T,K110T,E132K,E145R	0.159781842926162	0.111373798356642
N31Y,C75D,P88L,N121V	0.0349063093008885	0.0986353830448808
N31Y,E132V	0.101895739204946	0.107279060664045
N31Y,G90R,E122G,Y137N	-0.26174205793199	0.130920757591409
N31Y,I45V	-0.629407264276509	0.173553759664667
N31Y,K74T,V142K	-0.0754103098000642	0.131995557644933
N31Y,L38P,P46R,L63P	-0.134898099354583	0.124015386535185
N31Y,L63P	-0.0091622232649009	0.117976691726749
N31Y,L81I,D102N,A152P	NA	NA
N37A,C43Y,V86A,Y137N	0.240013099147546	0.108934479133801
N37D,A131G	NA	NA
N37D,A131G,V148A	0.906306448579761	0.111125471920899
N37D,A131P	1.02185731253674	0.108894896096186
N37D,C138Y	0.012314605044272	0.123148455026258
N37D,D66A,K76R	1.52414465099902	0.223623564795523
N37D,D67N,I112V	0.773393685628002	0.0255667789907284
N37D,E122V	0.562289340629403	0.108053320260302
N37D,E132G,N140D	0.595623847502478	0.0991073446557267
N37D,E132G,R141G,Q151R	0.147241791455152	0.174359694577943
N37D,E99G	1.75286235159055	0.103836023448767
N37D,E99G,K154E	1.76406499235346	0.108994201564513
N37D,I45V,P72F,I109T	-0.0937334246534998	0.137445817999875
N37D,K101E	1.53898428542049	0.0978752698486277
N37D,K101E,L113Q,N140T	0.811166811613589	0.203019585348608
N37D,K101E,S158P	1.36595849963742	0.259959181308316
N37D,K48T,P73S,Q111K,L119P,N121T,N140K	-0.356836343820337	0.181993646220292
N37D,K49R,I107T,L119F,E143G	0.326397762147444	0.0406448361793598
N37D,K74R,C138G	0.302647833386563	0.110840057624506
N37D,K76N,Q126K	0.813719385834838	0.0758400772388352
N37D,M39T,I116V	0.686095997035739	0.162436386376176
N37D,M62R,D66E,K74S	2.29741244353818	0.125189729193159
N37D,N124S	NA	NA
N37D,S89L,E132D	0.073585840597796	0.208557119370262
N37I,E54G,K101R	-0.212090204394305	0.109363918134484
N37I,F58S,K65I,C75R,K110E	0.136321753477918	0.106217663860105
N37I,L114I,E122G	0.369623925459564	0.193698783854751
N37I,V86G,K101R	0.406545919436791	0.104497235759987
N37K,F77V	0.556298536805167	0.143360914498406
N37K,K76N,I109T	0.0149833967807259	0.120003436061855
N37K,P72Q,T108A	0.417931499168045	0.0904479346203509
N37K,P72Q,T108A,I136S	0.303094913145741	0.18110153136623
N37K,Y144H,A156T	0.820122219624613	0.187766577924557
N37L,K76T,N85S,I109T	0.211634033607574	0.153842619206709
N37L,R149F	0.0775616205233121	0.145529521162883
N37P,L113K,N124H,I136V	0.177537508610517	0.255176986316816
N37R,P72L	0.135676642741148	0.164974584283191
N37S,A133E,E143G	0.917854315558487	0.129453690626269
N37S,D127G	0.323084885179207	0.144748494129578
N37S,D66C,Q117R,A152V	0.213232934251625	0.0798689669033248
N37S,D66E,N140S	0.503366344934226	0.176109395735799
N37S,D66R	-0.109380724293435	0.183975190055986
N37S,D67N	0.872016419999822	0.0987604869243795
N37S,D67N,R141G	1.21801082411829	0.180690462043065
N37S,F58L,A150V	NA	NA
N37S,F64S	-0.0309399273344533	0.105190448472852
N37S,G47E,T51I,P72L	0.192890343929687	0.113207617358583
N37S,K110R	NA	NA
N37S,K59N,N124M	0.213465290233011	0.115613780822134
N37S,K65E	1.91546405933305	0.159784006964146
N37S,K65R,P84S,E99D	-0.056805410329582	0.111161253325322
N37S,K74E,I109V	1.39123697356086	0.10112558113932
N37S,K74M,E122F,I136T,K154C	-0.145767189995924	0.188036378787728
N37S,K74R,H83L,S95P	1.74217485548209	0.208608779666615
N37S,L57I,D66Y,K76E,L94P,I116V,Q126R,Y137F,F155H	NA	NA
N37S,L63P	0.112736509690121	0.18497232006824
N37S,L97S	0.51937678033392	0.0644809671613496
N37S,M39T,K48E,T51I,K101E,A106G	0.270451617704664	0.187681312741919
N37S,P88S	NA	NA
N37S,Q111L	NA	NA
N37S,Y134H,E143G	0.543880937335304	0.177883138092728
N37S,Y87H,A133P	0.0799521447506251	0.157668032265761
N37T,D66Q	0.153800586339497	0.155967564942729
N37T,P79H,E132G	0.833253226224975	0.100542812369307
N37W,D66S,L119G	-0.0989756773771181	0.120969009553684
N37W,P72Q,P105S,N121L	0.0798317160854862	0.10309961099169
N37W,P73N,I107G	0.110518958143333	0.113130707179411
N37Y,G55R,S70P	-0.15493896761722	0.106962888389084
N37Y,G56D,P80L,N124Y,R147G	0.852328423248659	0.183380514716813
N37Y,S95P,Q126R	-0.155324908722347	0.121241673549447
N40D,A106T	0.581900123393314	0.0995878246217278
N40D,C75K	3.02689462081778	0.151067931038612
N40D,C93S,I107T,L120P	-0.0378854754461836	0.0512340164607416
N40D,D66G,K110R	NA	NA
N40D,E122G	0.145893913573738	0.0817459410438227
N40D,E54M,M62I,P105G	NA	NA
N40D,E99G,I109C	0.591020442057039	0.198323772366816
N40D,H83L,E99A,L120V	0.33489350540267	0.140759370203297
N40D,L63V	NA	NA
N40D,M62T,I112W	0.198845729365511	0.115558816168898
N40D,M62T,L97I	2.47110887544345	0.187609921678478
N40D,P52M	1.23061476806429	0.0997827932987892
N40D,P72S,H83R	-0.0342368167205578	0.105622958957278
N40D,P72S,H83R,E98K,I116T	1.90317461527103	0.226577829917025
N40D,Q126R,R147S	0.487857539783922	0.128529953331842
N40D,R104A,E122R	0.54493353679246	0.140043320051058
N40D,R104P,R147P	0.000109148324061436	0.156205626730703
N40D,S158L	0.848704907945911	0.114094001279579
N40D,W103E	-0.250828221555695	0.158556595207438
N40D,Y68S	0.100792980117198	0.110811463691037
N40I,D102E,L120Q,N124K,N140S,K153M	0.0637376648241744	0.0818186772058227
N40I,I125F	-0.159695507139972	0.105300671109632
N40I,K110I,P157S	0.61871269143543	0.204691318178783
N40I,R104M,N124S,E145Q	0.539758846708583	0.118130797692527
N40I,Y87H,Q151R	0.0594362268995415	0.116572206666375
N40K,A129P	-0.0406271611335456	0.101374449566483
N40K,I125T,Q126R,Y134N,C138R,R141S	0.106197514241595	0.122413360054875
N40L,E42V,F82K,R104G,N140I	-0.251808211781554	0.219735871869183
N40S,C75R,V86E,I109T	-0.0953726464103417	0.0975137066468694
N40S,E122M	1.42048353554722	0.157626317060864
N40S,E54V,E98K,E145V,F155L	-0.25215405437609	0.119679610415235
N40S,E54V,K74S,K76I,Y87H	0.119262353976946	0.12004977192875
N40S,F64S,K74E,K101R,K154R	NA	NA
N40S,I107Q	1.37533698782958	0.109229854553277
N40S,I116V	0.458713173663914	0.105375732318837
N40S,K110R,I112T	0.538963449201498	0.206044527548965
N40S,K110R,Y144C,F155Y	1.00470155166315	0.219182824382126
N40S,K49E,H83R,D127G,R147S	0.00725017504038717	0.176329956809379
N40S,K49R,V92A,D100G,N140I,R147W	0.345015303533442	0.178092560206021
N40S,L63P	-0.204611770669809	0.125152046867099
N40S,P46S	0.437753420613644	0.115639532258094
N40S,P79V,E118S	0.834110376632267	0.142445988645251
N40S,V86E,P105A,I107T	0.323852404292741	0.156861754612824
N40T,P52N,I109C,P123T	-0.327353128390129	0.151315515857194
N40Y,D100G	0.541072438789535	0.104270579768499
N40Y,S70P	-0.428911515246512	NA
N85D,C138Y	-0.155345864401439	0.0421280940519219
N85D,L119P,Y134H	NA	NA
N85D,W103K,N124F	0.244084476587797	0.119646377793718
N85D,W103R	-0.368204964791122	0.101900449769627
N85D,Y134C,K153R	0.445760965293607	0.109088363321267
N85H,L120G	-0.163283789680287	0.163454085656854
N85I,K101L	0.0311634550534922	0.115101178992857
N85K,G90E,Q130L,A152G	0.13578881604335	0.0855466993448984
N85K,N140I,S158L	-0.54449978583993	0.113267025721435
N85L,A133C	0.167432769387325	0.179239441807543
N85P,W103R	0.0939012860384696	0.110074656529291
N85S,P105T,I112V	-0.0984881779415241	0.143281054879112
N85Y,C138R	-0.447069631729485	0.0999320837702712
N85Y,D102V,K110R,V142A,V148I	NA	NA
N85Y,E132G,P157L	-0.0992692360020641	0.113890968182159
N85Y,N124Y	0.288260829728143	0.186992983091377
N85Y,W103C,T135M	0.018271145317722	0.125032080691232
N85Y,Y87H,I109T	-0.440944245301961	0.205308088047568
P105A,N140D	NA	NA
P105K,D127F	-0.460215358428494	0.163442187529655
P105L,E132K	NA	NA
P105L,I107N	0.459974764963259	0.184738310596473
P105L,I112N,I116V	0.289423451269925	0.214510726321498
P105L,K146E	0.044313828696354	0.0976189484413779
P105L,P123L,N124K,A133T	NA	NA
P105L,Q139L	0.249018198803479	0.121164411721498
P105R,L120W	0.61262979440099	0.249319415468802
P105S,E132K	0.220157774457397	0.116636311821721
P105S,K110E	0.152594634129993	0.0767908175451103
P105S,K110E,Y134H	0.418626060799969	0.187831189313739
P105S,K153N	0.0908796314902805	0.184324071972972
P105S,L119P,N121D,E132K	-0.213265057969806	0.286994919980769
P105T,E118S	-1.67633322541432	NA
P105T,I107N	0.693821173772165	0.134795908766586
P123L,K146E	0.129998162249938	0.219938408752543
P123L,S158A	0.0765744948599729	0.111679065031989
P123L,V142G	-0.112765117380649	0.0977687939645009
P123Q,R141G,S158P	0.182421631076515	0.0830743049394011
P123S,Y137S,V142T	NA	NA
P123T,R147K,A152P	0.2913456029615	0.167939203476866
P123V,Q130H,K146C	0.590453590740846	0.107780665886671
P128A,E145G	0.527017231293835	0.103377403835749
P21A,N40Y,R104G,I136L	-0.0105975908939663	0.143149029630156
P21A,N85D,E99K,Q139R	-0.237198181527102	0.253691611366007
P21A,N85D,E99K,Q139R,Y144M	-0.27871131859444	0.176075766060812
P21A,V25M,I112T,Y137F,A150V	0.778222994854141	0.151077824600425
P21A,W53R	0.0488049980255911	0.0514397071241214
P21A,W53R,M62R,I109V	0.308769079133647	0.16005893321786
P21F,P105K,Y134D	-0.253184042850702	0.106185098131101
P21K,L60G,L63P,C75G,Q111H,N121V	-0.0861376845445107	0.116965399560819
P21K,L60G,L63P,C75G,Q111H,N121V,V142G	-0.363838994390781	0.303482003066174
P21L,C93S,D102E	0.000491753424451348	0.245045639932832
P21L,D127A,E145G	NA	NA
P21L,E145G	-0.382585229397091	0.23180867347667
P21L,E98G	0.53215752232275	0.0802384643316911
P21L,I96F	0.330501533422421	0.099281949241235
P21L,L38P,M62V,C138W	-0.116922614219415	0.0617403865421588
P21L,V25G,K65R,E98G	NA	NA
P21R,M36K,P72R,T91A,V92Y,Q111R,Q139G	0.0318288396221332	0.0375303499223306
P21S,C75S	0.14143915358115	0.0409364197447956
P21S,L63V	0.360789326939871	0.206472054632651
P21T,C43Y,F64S,P69S,F82S,R147G	0.0204192301333136	0.210432661662914
P21T,D33G,R147G	0.362930900385994	0.164944013707423
P21T,K101R	0.44228199394118	0.153650346525686
P21T,K30I,E122S,N124S	1.03793337126666	0.231726708670881
P21T,K30I,N124S	0.331026010452561	0.10344543211176
P21T,K48E,I109V,P128A,Q130P,Q139H	0.743703102445172	0.164896360701087
P21T,K48E,P128A,Q139H	-0.33471333866712	0.249012708696231
P21T,L57M,F64S,E145G	0.0911549937847623	0.230254956344045
P21T,L57M,F64S,L119P	0.0735992329121474	0.171969261084422
P21T,L57T,F64S,C75R,P79Q,N85S,E143G,Q151R	-0.0339172142463678	0.208532122628227
P21T,Q130R	1.68468147633851	0.195269898299397
P21T,R61L,I107T,N140S	0.531179104895967	0.181841334854121
P21T,S95Y,L113R,R147G	0.339310525574936	0.121321060427013
P28A,I125T	-0.12613555304039	0.185550471179959
P28A,M36G,F58S,F64G,C75W	-0.043304919543903	0.178529594628519
P28A,N85S	0.139329582293564	0.108757796636148
P28A,P52A,L114A	0.596925613786563	0.0998842493360135
P28A,T51S,I125T	0.88696391859047	0.139928710222158
P28A,W53R,F58S,P73Q,C75W	0.113327161186337	0.167238479988992
P28E,L81S	-0.112657734907734	0.101699989872761
P28F,F82L	NA	NA
P28F,F82L,F155I	-0.227426352974575	0.117155911114689
P28L,D127G	-0.0778636092107499	0.199024834775182
P28L,D127L	-0.0382367116971895	0.122471347948091
P28L,I112V,A131E	0.231037916239336	0.0999300477537959
P28L,I116R	-0.34985857726578	0.135980231156208
P28L,K101E	0.139706824283687	0.124007746407451
P28L,K48M,G56V,V142A	0.600402711456934	0.182759825372707
P28L,K49N,K76E,T91A,C138R,K146R	0.034163740847071	0.266784045817457
P28L,K74E,K76R,A152T	0.365924750342332	0.118598274052367
P28L,L81D,D127G	-0.0225190144822912	0.0760894975685917
P28L,R61L	NA	NA
P28L,Y68N,K76D,I107G,E122K	NA	NA
P28Q,A156P	0.537004946251733	0.204762149462524
P28Q,D33E,A106T	0.396596643530128	0.113775138871966
P28Q,D67L,I112G	0.12534904636611	0.0396414255142292
P28Q,F58L	NA	NA
P28Q,F77R	-0.43272138824573	0.159089281392945
P28Q,K101R,E122I	-0.192199660311123	0.116850758066501
P28Q,K48N,D67G,I125S	-0.0229162032532701	0.12987749428494
P28Q,K65N	0.236004064928436	0.0360392273797882
P28Q,Q139H	0.442780074619441	0.0762223495707246
P28S,E122V,D127G	-0.368982649750818	0.113086089558609
P28S,E54G,A106V	1.07551306271799	0.10433128997581
P28S,F64S,P79N,Y87D	0.247915193264252	0.14298021464483
P28S,G34K,I136R	0.355043587104791	0.107523928017955
P28S,I107V,K110R,K154T	0.400247561747101	0.173010009289074
P28S,I107V,K154T	0.302315444270493	0.102851558095483
P28S,K74Y,D100A,N121V	0.805916598280233	0.231641049738158
P28S,M36I,K74P,I96T	0.152206975107214	0.134372246956971
P28S,N121D	0.660337159236705	0.122721546825251
P28S,N121S	0.693060918459606	0.115948094630505
P28S,N121S,Q130P	-0.0950951214815088	0.0615926059644787
P28S,N40S,C43R	-0.0338251492340111	0.114663921439909
P28S,S95Y,I112T	2.56013521619311	0.22246263041282
P28S,T108L,K153H	-0.351673324658117	0.192881546844947
P28S,T51A,N85Y,I109T	0.0524283225663003	0.0995895161851247
P28T,F155L	0.71604360592898	0.22502376253878
P28T,I109V,F155L	0.527504286568944	0.134973429348458
P28V,M39V,N124Q	-0.0567359564215334	0.113251692592922
P28Y,C43R,K74T,E118A	0.11757317192212	0.116998163527729
P28Y,Q126A	0.141752790578297	0.109607033404606
P32A,D67N,N121L	NA	NA
P32A,F77R,H83R,L114S	-0.233686516220223	0.126212835840058
P32D,D102V,R141C	NA	NA
P32E,G115S	-0.175225548789534	0.143931749531403
P32H,C75S,F82L,A106P,L120I	-0.0658227369909354	0.0826513108341989
P32H,C93R,I109N,K146E	-0.262513584792748	0.122442750714924
P32H,E118G	0.391458943877291	0.0348185318423674
P32H,I107L,N124S,A152T	-0.112063541630595	0.114282105532052
P32H,K48E,G90E,R104W,I109T,E122G	0.636764439439582	0.142915088170749
P32H,K74E,C75S,F82L,A106P,L120I,K153R	-0.41694191683893	0.271497574033245
P32H,K76T,I109W	0.142361427534511	0.109887923658932
P32L,C43Y,N124S	0.311981968498164	0.226976837408677
P32L,K76N,E122L	NA	NA
P32L,L119S	-0.250353058487744	0.190128508740475
P32L,L60Q	-0.0936351616108875	0.114927852282359
P32L,L97I	1.67806493216449	0.102288629997052
P32L,L97I,L119P,E132G	2.32508152672735	0.1564546128547
P32L,M36V,P52T,C75R,F82S	0.12624428354445	0.160902624376334
P32L,M36V,P52T,F82S	0.075984773861217	0.13219414593725
P32L,N37I,I96V,I116V,Q130L	1.42098563164904	0.16068896238248
P32L,N85S	-0.141066277302381	0.171568148458127
P32L,R104K,L114F	1.01242098527967	0.164068522951793
P32L,Y137C,R141G	0.83955944061165	0.146370949834475
P32M,A106V,E118G,E132G	1.52455224216103	0.190520078295063
P32M,K59N,K76E,E132L	-0.25787943773982	0.16707154109727
P32N,C93R,E143V	-0.165944955548016	0.117427231807325
P32N,I112V	NA	NA
P32S,C138G	0.0254532473261903	0.185990452966443
P32S,F77S	NA	NA
P32S,I45V,P73Q,C75F,S95P	0.204951462904649	0.165717998615492
P32S,K65Q,P105L,E118V	NA	NA
P32S,L81Q,A133T	-0.125977721464074	0.121865303674919
P32S,M39L,I45N	0.698530794634537	0.11679744413582
P32S,P73Q,C75F,I109V	-0.0507985730280439	0.14519688244654
P32Y,D66T,V142R	0.204090537785861	0.108249799502793
P46A,K48R,L114P	-0.109986134912684	0.127746987119906
P46D,M62R,F77P,I109K	-0.165730343978338	0.140314442359759
P46L,C138S,R141T	NA	NA
P46L,E122V	NA	NA
P46L,F64L,I96T	0.681302626640222	0.119073346656398
P46L,G55R,V92L	-0.139164753457283	0.12960041016101
P46L,I96T	0.445609301334167	0.101254798725624
P46L,L63P,S70P,I96T	0.847554496672522	0.113470795278135
P46N,Y68R	-0.0452846872303133	0.127806661631875
P46Q,M62R,F77S,I109K,Q139R	NA	NA
P46R,N124C,Q139T	0.223441377655398	0.119857489199249
P46R,Q111T,N124K,E132L	0.440306688592243	0.17155744772845
P46S,I109L,R147E	0.218330169333396	0.159209973566969
P46S,L113G	0.285555156339983	0.145544553612593
P46T,E132G	0.165004162827587	0.110813123401171
P46T,K59E,D66E,P105L	-0.391737878465997	0.121165046397144
P46Y,T51A,I107E,E132A	0.427201666552984	0.111054572287819
P52A,I125V	0.506674313710787	0.175396374722564
P52E,A129G,Y134W,T135A	0.133629163255755	0.145820280936257
P52F,V86E,L113V	0.155261732444184	0.157152201410471
P52G,I136V,K146E	-0.329538623646928	0.162718629917526
P52K,I96T,Q126V	0.319994092720173	0.0991215498999135
P52K,N121V,I136D	NA	NA
P52K,N85K,P123I	NA	NA
P52L,Q117R	0.201425595338968	0.109522074666891
P52L,Q117R,Y134H,E145V,K154E	0.310182589327534	0.180377829186576
P52L,Y68H,Y87N,R141G	-0.210099079502608	0.108954518827894
P52M,A133T	-0.14671221411469	0.149900875859844
P52N,V92A,P105Q,D127A,R147K	-0.483490113283902	0.124213774286961
P52R,H83C,C93G,A106L,N121S	0.407720083852868	0.106556571184671
P52R,P69T,I116M,K154M	0.113286040738292	0.128562658368221
P52R,Y68K,N121D,V142S	0.0978590049616829	0.108047922603417
P52S,I107M,V142A	1.82836818446415	0.107644700539765
P52S,V92A,I107F,I112T	0.504002543747328	0.123291389649359
P52V,L81Y,D102W,I125R,V142R,F155Y	0.142537903379724	0.113197062479162
P52V,R141L,K154L	0.0400292223271005	0.109525340685052
P69A,I112K,N124S	NA	NA
P69D,F82M	-0.328460691599496	0.149928047189477
P69E,L113W,E122D	-0.351128012505756	0.104454890081147
P69I,I125G,E132K	NA	NA
P69K,L120R,R141G	0.176468396594071	0.117060294555909
P69L,E122R,E145M	NA	NA
P69L,G90R,I116V,Q139L	-0.334033774262737	0.204738332584283
P69L,K76E,L120G	-0.0231240640122088	0.109817689477574
P69L,N85S,Y137H,Y144H	0.0707286207119981	0.094991163748841
P69L,Q117L,I136F,N140D	1.01682024167762	0.167740746550248
P69M,I109S,N124K	0.0482966897529774	0.0992432667262687
P69Q,S71P,F82P,K110T	-0.00042804369879768	0.130629312030551
P69R,A131V,K146I	-0.013141504214677	0.216155810763454
P69S,C138R	0.206450118871429	0.0320765968527907
P69S,F77L,N140D,K153E	NA	NA
P69S,K76Y,F82S,A133P	-0.215687641381999	0.0995196266660644
P69T,K76E,A129V	0.43214998453446	0.157773625275581
P69V,E78G	0.201845975808619	0.202017614748857
P69W,L114R	-0.132788356378825	0.102285193212041
P72A,R104W,N140D	NA	NA
P72A,R104W,P157L	-0.436419505399481	0.0939397315280349
P72L,D100Y,L120V	-0.284760823333769	0.122458092241365
P72L,E118D	-0.0932049305842519	0.1217419568136
P72L,I109N	-0.0432860120726843	0.103886971701717
P72L,Q117R	0.00762717283326334	0.135487866388167
P72M,H83Q	0.119282623066034	0.11744292799159
P72M,N121D	-0.194325988175122	0.231651425155632
P72Q,A156T	-0.542118979228412	0.253174255719106
P72Q,L113Q	-0.11593489314136	0.147582915864736
P72Q,T108A	0.0863185596519443	0.147570983500433
P72Q,T108A,A131V,Q151R	0.123435527501647	0.21787349469384
P72R,I96V	-0.369535788278897	0.112940852953775
P72R,Q117T,R149T,A156V	-0.355612190038551	0.160773536878375
P72S,Q126R,A156G	1.15463509431325	0.108753675173693
P72S,Y134F,T135S,V148Y	-0.263061161398986	0.17656751194594
P72T,A131E	0.263487737296482	0.133026485448707
P72T,Q111H,I136T	0.416840966040141	0.10575614955598
P73C,L114R	0.50697407428198	0.177784518288138
P73I,K110G,N121F,E143G	-0.113256369666835	0.0463194117656679
P73K,I125W	-0.0986225929802372	0.105380773762021
P73L,I109C	-0.144251276591825	0.17645980507432
P73L,N121D	1.19356944543985	0.22177963451546
P73L,R141W	0.145162099954268	0.168232814383133
P73L,W103R,T108P	0.119717470217883	0.156212058546795
P73M,C93G,T135R	-0.237018332010347	0.146789158341882
P73M,L119P,N121E	0.271410308060446	0.108952933044734
P73N,K154Q	0.148700980323146	0.125363356175946
P73Q,E143G	NA	NA
P73Q,N121D,Q126P,K154R	-0.156637921613327	0.133494711599425
P73R,A106V,L120Q,K146E	0.381603203566716	0.176490813445082
P73R,D100G,L120Q,K146E	0.769585527325014	0.164648710306581
P73R,E145G	0.0713353222156654	0.118273430427658
P73R,I109C	0.472055412167064	0.155434950845165
P73R,L120Q,K146E	0.208347564533133	0.175735139713824
P73R,P123E	0.0529291732552921	0.11043757654848
P73S,I107T,I112W,Y134H	-0.0927112594588758	0.143341793936894
P73S,I116L,Q126M	-0.12736123707397	0.135607096847037
P73S,K74E,N121S	0.270867060621651	0.23780921385064
P73S,L114R	0.0588310962256305	0.0541458891233849
P73T,I107V,L114R,I125T	0.263625946606039	0.136655849512325
P73T,N85T	0.502500619702659	0.104381575356706
P73T,P84L,P88L,I125F	0.263988490981611	0.147457993643228
P73T,S95P	0.538758136583443	0.141101202401533
P73V,V92E	-0.037698052915557	0.143625061457899
P79A,E118T,E132F	-0.496409606453719	0.148962764085639
P79E,A106V,N140D	0.9075700461487	0.161593794756144
P79F,D102G,N121F	0.786753413135171	0.0974230537636401
P79G,T135Q	0.458068522201133	0.10967646677374
P79L,C93S	0.393423374882897	0.121562891353519
P79L,Q111S,Y144H	-0.127315896844502	0.0459698490243293
P79L,W103C,A133P	-0.121587430888202	0.0565323089814916
P79L,Y137S	-0.41348310728221	0.233527893981821
P79L,Y87C,S158P	-0.157199348029311	0.345804685649271
P79N,A133M	-0.17442814872678	0.111108536201246
P79R,A156T	-0.186129229015033	0.128339283618002
P79R,I136F,N140D	0.599644763755765	0.10724306722426
P79S,I116V,N124R,V142P	0.468666684285149	0.120091555060619
P79Y,P105G	0.686718646102864	0.185028816063849
P80A,Q111V	1.21310594966088	0.128116420415219
P80I,W103T,Q117R	0.138319792664255	0.144180995948454
P80L,I107T	0.180426579822657	0.10915108423924
P80L,I107W	NA	NA
P80S,I112V,E118H	0.507650607627195	0.178347647025208
P80S,N124Y,R149G	-0.0223688245119483	0.137804324929999
P80T,P84S,E118G	NA	NA
P80V,E99K,R104K,E122M,C138H,F155L	-0.0185018733888375	0.117870172709479
P84F,I109V	NA	NA
P84L,I136C	0.916188552560515	0.116944474513818
P84L,P88L,A106T,K110F,I125F	0.158691807540325	0.183266002448652
P84L,P88L,I125F	NA	NA
P84L,T135A	0.651445409726099	0.102040439823501
P84M,Y137C	-0.322881375559066	0.181773439197233
P84Q,N85D,Y87H,I112T,P123S,R149L	0.178821508400412	0.128395325155586
P84S,K110E,L120P,N124D,K146R	0.362987278490388	0.172593985325438
P84S,Y87K	-0.0167460779321416	0.127511749926801
P84T,Y134H,T135S	-0.0832015780858203	0.108223170808065
P84T,Y144H	-0.0973945364496446	0.121182555594903
P88H,I125T	0.307717576075631	0.099616436795956
P88H,K110R	1.00546941268186	0.0997943477460084
P88H,N121L,A150W	-0.13400788904643	0.215719674125983
P88S,Q117R,I125W	0.43356299203924	0.12536543792689
P88T,E145G	0.280335378819579	0.114288163289003
P88T,N121S,A150V	0.534852538285514	0.111961664365246
Q111A,Y144C	0.000705686837911744	0.158685002885243
Q111A,Y144S	0.0631248074770045	0.117563486837464
Q111E,E118M	0.0372168520764754	0.134411227994924
Q111H,E118G,T135M	0.8703077673911	0.184943783827427
Q111L,I116T,E143G	0.376749470623317	0.218582213831689
Q111L,N121Y	1.50643869390203	0.110388568155139
Q111L,Q117K	0.1467929867501	0.113580932683779
Q111L,V148A	0.635039503721102	0.117805777634223
Q111L,Y144N	-0.287139126933225	0.115139234295737
Q111S,P128R,V148A	NA	NA
Q111S,V142A	-0.309940978801861	0.145066416158313
Q111S,V142G	2.1721389970298	0.124890990954198
Q111V,A150S	0.222869239739967	0.146756064551452
Q117G,E132S	NA	NA
Q117G,E143L	-0.034165933545727	0.11648383085287
Q117H,D127N	-0.194846789148886	0.0636894992137663
Q117H,K146R	0.43096097904341	0.108611332280187
Q117I,D127A,E145D	-0.106266988247537	0.103212437841794
Q117M,A156K	0.172982674567431	0.0979360764196521
Q117P,Q126L,T135P,E143T	0.361423144998954	0.120486551481326
Q117R,E122V	0.279259447284705	0.11088398354479
Q117R,N121D,R149Q	0.553059064616961	0.0994430575095297
Q117R,N140D	0.67232893127481	0.0315480191904823
Q117R,Q126E	0.601765839481002	0.11086005187017
Q117R,T135A	-0.187856391558095	0.102601054016356
Q117T,Q126P	0.0243897024066505	0.105025793311317
Q11A,R17G,I45N,F82S,Q111L,P123Q,A150M	0.314687852337672	0.19475790965032
Q11E,N85S	0.231695776329872	0.106649477985365
Q11E,S71R,I109K	-0.151566960123412	0.101788621174495
Q11E,T51S,L113S,P123K	-0.217546431818206	0.121347688324582
Q11G,D66R,L94R,V148T	-0.0646492165531755	0.125029212602591
Q11H,G34V,G90R,I125F,K153M	0.0784455932110725	0.107040195833753
Q11H,G34V,I125F,K153M	0.145151328293395	0.124769235360961
Q11H,K49N,K65R,P157T	1.60595047091211	0.109529001104294
Q11H,K59R	0.510539182299355	0.0983077685016311
Q11K,I45N,L57Y,S95H,Y134V	0.249533775894372	0.0838523417702468
Q11K,K76M,H83R,I116L,E122G	0.406769386017931	0.244948079856756
Q11L,E99V,K153E	1.36316626674139	0.102170318132254
Q11L,L119H,Y134H	0.521433704027703	0.162798055126737
Q11L,T51A,N85D,G90R,S158L	-0.45816464353907	0.131326270530202
Q11P,K110R	-0.178199318362626	0.127283030434365
Q11R,D67V,F155S	0.00981660884021133	0.104986794192052
Q11R,E54V,G115E,R141G	0.251870579407308	0.203646021697198
Q11R,H20S,N37D,P52K,D66Q,F82L,E98R,Q117D,Q139F	-0.352665466361861	0.109508251404244
Q11R,I45T,P69T	0.059207889264291	0.111820446803097
Q11R,K14R,K30R,N121S	0.46947433057892	0.105642011346688
Q11R,K153R	2.11697895903958	0.198015391376784
Q11R,K65E	-0.0957580315761444	0.126732715153958
Q11R,L63V,R104G	-0.318450598822913	0.145461254037653
Q11R,N40D,L120G,D127G,Y144T	NA	NA
Q11R,P28Q,M62L,V142K,K146R	0.714633319493396	0.115758214173776
Q11R,Q111S	2.28870130228761	0.300898383319867
Q11R,Q130L	0.138457296417918	0.112796886129422
Q11R,S70C,C93R,P123L	-0.00377843479445602	0.179800405847231
Q11R,S95A,T135A	0.0631900243830153	0.112081372467321
Q11T,V25Y,K76P,T108A	0.0207181808144875	0.124676822897254
Q126H,D127G,I136T	0.377368791253173	0.11667253825745
Q126H,E143G	1.11969541894015	0.217807036301139
Q126I,C138R,K146E	0.98277562776896	0.125442477984957
Q126R,A150N	0.604676386303307	0.15740632433806
Q126R,D127H,V142E	NA	NA
Q126R,I136Y	0.282503891304158	0.114880496605191
Q126R,R141G	0.481764122204716	0.145149748363183
Q126R,Y134F	0.424637523398313	0.105947229204643
Q130H,Y134C	0.0389222619525794	0.1095746308453
Q130M,K154R	NA	NA
Q130P,Y134C,R141A	-0.161084752497078	0.193423993030968
Q139K,A150T	0.129509809235815	0.12999842511635
Q139L,K146E,K154M	NA	NA
Q139R,K153E	1.22147586539354	0.0987998986539148
Q139R,V142M	NA	NA
Q151R,P157S	0.105402547103502	0.13807316817098
R104A,R141N	0.57472291196445	0.100838213863897
R104G,E118G,D127V,Q139L,R141S	-0.0867320181757724	0.108913781912783
R104G,Q111F,R147Y	-0.194294696379431	0.160321839717002
R104K,A150W	0.317495050122101	0.190867178514923
R104M,I107N	0.425676846742694	0.117354489615164
R104Q,A133P	1.48015327894722	0.141073503262267
R104S,D127G	NA	NA
R104S,I125N,C138S	NA	NA
R104S,K146R	NA	NA
R104S,R141S	NA	NA
R104W,T135K	0.721316258909145	0.145138814943152
R13D,A133F,Q151H	0.344878284050344	0.109809475032228
R13E,K49M,I112T	NA	NA
R13E,K76R,D102N,A131S	0.430223887942305	0.191643089684856
R13E,R147L	-0.0053659793932672	0.0443067763886421
R13E,T51A,T135N	-0.146942779941625	0.148710160207863
R13G,A156V	0.471162122112873	0.115164272714163
R13G,C43R,N121S	-0.583367820962193	0.174039682006976
R13G,E42G,L81F,Q111R,Q139H,A156V	-0.0556103234369509	0.118889858792389
R13G,F64L,K76E,I116V	-0.287989548045962	0.0641175900759788
R13G,H20Q,T51S,C75S	-0.13780209635906	0.112930635344802
R13G,H20Y,D66F	0.70763853340677	0.108594321929724
R13G,I107V	0.033305959040357	0.131750668219062
R13G,I112V	0.137099774735845	0.0728356193617259
R13G,I116T,N121V	NA	NA
R13G,K14E,C43R,L119P,C138S,P157L	0.00151643173997525	0.179160621514418
R13G,K14E,E118G	-0.10758787205432	0.0555837497351033
R13G,K14R,P52M,C75H,Y134H,E145S	-0.130966073960843	0.135891105467803
R13G,K14R,R141I,V148A,A150V	0.159359241659582	0.100698182397112
R13G,K18E,Q139R	0.00248012066443302	0.12400102068811
R13G,K30E,S70F,C93S,I96V,I112N	0.282406901956761	0.129903315621895
R13G,K48E,T51A,K146R	0.0708544235649575	0.163190117585926
R13G,K65R,N124D	0.147749070929695	0.188830874201498
R13G,K74E,L119H	0.145716550692498	0.116545466415715
R13G,K76E,F77L	-0.0083083504663197	0.1176039099705
R13G,L113Q,Q130R	-0.307185241521335	0.250030742164959
R13G,L63P,I136M,A150D	0.386549938356991	0.138655904652635
R13G,L94M,I125T	-0.101539279181943	0.134038337003605
R13G,M62K,E118G	-0.236770426991059	0.108518611201789
R13G,N124D	-0.29671274875256	0.124517878129386
R13G,N37I,F64L,P73Q	0.138980294238918	0.0551717745978022
R13G,N37I,F64L,P73Q,E98G	0.553123027962898	0.172717048497085
R13G,N85S,N140S	-0.129667010960049	0.133701959422778
R13G,P28S,N40S	0.00589104610161836	0.238105718128246
R13G,P69K,L97F,I107V	-0.303870571489495	0.177104116955914
R13G,Q111L,L120P,N121Y	0.152942116468305	0.188719220740172
R13G,Q111L,N121Y	0.0272649666441174	0.114922939271714
R13G,R149L	0.0150704785737361	0.172478176208278
R13G,S158P	0.213939098997797	0.129532283661798
R13G,S95C,A129T	0.495731323439619	0.111559121049394
R13G,V92T,A156V	NA	NA
R13G,W53R,F64L,K76E,I116V	0.104850584884558	0.167024958974043
R13G,Y68D	-0.363883875606512	0.120388253720553
R13G,Y68H,S95C,A129T	0.143993855067918	0.158481973078525
R13K,D66P,Q126R	0.301391953768015	0.112897049711438
R13K,E145F	0.0155051860772618	0.139307987298334
R13K,F58V,Y134C	0.0343444152525699	0.105234639593819
R13K,G47R,Y68C	NA	NA
R13K,H83R,V92M	-0.0356472242456073	0.112276630589497
R13K,I107T,A133H	-0.271657742878423	0.177956645044046
R13K,K18R,D33V,L60N,K76W,H83Y,V92M,A106L,I125V,K153D	-0.125840941178334	0.119522404669614
R13K,K30T,E54S,Y68N,R104K,R141C,K153I	NA	NA
R13K,L60N,Y134C	-0.588958304876171	0.177056121155392
R13K,P52W	0.0557609916304081	0.08879894510557
R13L,H20L,A26P,K59S,M62V,P72L,H83K,Q111G,T135L,A150K	-0.159463037210395	0.0415877807962699
R13N,F58I,R104L	0.00143217424869292	0.122684478462568
R13P,M36I,K59R,P72L,T108W,Q126K	-0.296199884703625	0.119289998511368
R13Q,F24S	0.384400279986351	0.116426236091179
R13Q,K18R,T29A,F58S,D66E,E122V	0.105756755529532	0.19805424648663
R13S,E54G,S71P,K154E	-0.0550955931002991	0.111872680465962
R13S,N40S,E54V,E98K,F155L	0.0107651945295103	0.0503872934895383
R13S,N40S,E54V,E98K,I107W,D127L,R147K,F155L	0.448593958626567	0.150707577066454
R13S,R104G	-0.143900357207529	0.109006166594721
R13S,W103R,N140I	-0.300454545418021	0.206034829636101
R13T,K59N,N121M	-0.961699914597509	0.202352281715238
R13W,L81F,I125T	0.265563679482296	0.131699594352865
R13W,M39T,V92M	NA	NA
R13W,N31L,M39I	0.418498113764503	0.180079650242205
R13W,N40Y,R61Q	-0.257621083810186	0.201043813712784
R13W,P69W	-0.0571334025770383	0.157785979119553
R13W,Q111R	0.173512550604453	0.109685527821397
R13W,T35A,M39L,H83D	-0.038102815159601	0.141048581411247
R13W,W16R,T91I,E118G	-0.389764141549598	0.43325950605083
R141G,Q151R	0.0782443972786055	0.0856924417706754
R141I,Y144S,V148A,A150V	NA	NA
R141L,K153S	0.496596773508835	0.128295837516156
R149L,F155V,P157L	-0.181978200658008	0.117843522739835
R17A,P72E	-0.209303442098872	0.103024499394843
R17C,T108A	-0.289359151150185	0.141684184603283
R17D,D33V,D66S,P79R,P105Y,E122C	NA	NA
R17E,G115V	0.00219560637010062	0.113789366033826
R17E,N31D,Y68V,L81P,W103K,L120R,C138P,R147L	-0.237728785378391	0.0403343224835441
R17F,L63P,H83R	-0.0991578715043512	0.150512541844388
R17G,C75S,D102Y,E122M	-0.0704049781801402	0.100218345096283
R17G,D19G,I125T,N140S,F155L	1.54556825337991	0.188510534872324
R17G,E118G,A150S	-0.0994107589340551	0.204882183548722
R17G,E42G,F82S	-0.0589953197810884	0.104732019508962
R17G,G23S,E122G,T135A,K146G	-0.324878921372602	0.0980172096170653
R17G,H20R,M39K	0.0995828965385898	0.113716237238683
R17G,H20Y,V148I	0.227914371879378	0.115274369470942
R17G,H83P,T108V,E122S	0.316898950876712	0.135545027958979
R17G,I116S	-0.0766970566596887	0.0774390078167133
R17G,I116V	-0.117960383510476	0.0614510429598499
R17G,K101R	0.271190907922581	0.103678165579839
R17G,K153R	-0.150493766589599	0.156928314636975
R17G,K74E,K154R	NA	NA
R17G,K74L,L81V,I112V,A133S,V142F	0.0190694472620417	0.128852456425849
R17G,N124S	-0.273149051106792	0.120315988339237
R17G,N31D,K48R,L57S,S95P,Q139R,A150V	0.0708091436043258	0.123581561768177
R17G,P28L,K76T	0.38284721558576	0.149152071229353
R17G,Q111P,P123F	0.143104958449172	0.168731580468949
R17G,Q126H	NA	NA
R17G,R61L	0.230551909222732	0.1423283775734
R17G,T29S,K30R,K59N	-0.0103791538360884	0.113561634317369
R17G,V148D	NA	NA
R17G,V25E	-0.10894507245854	0.120748630414467
R17G,V25L,N37S,L113R	NA	NA
R17G,V25L,N37S,P46S,K48R,F155S	-0.0635194160031264	0.103375327157817
R17G,V25M,N31D,T35R,K48R,L57S,A150V	NA	NA
R17I,E145K,K146R	NA	NA
R17I,P73H,I109T,T135P	-0.120871036150615	0.125187863901496
R17K,F22R,N31I,N40D,L60K,F64L,P73T,L94I,A106P,R141N,A156V	1.23653161195177	0.148841697702194
R17K,F64L,G115S	0.842631083633746	0.202819318855192
R17K,I107W,D127L,R147K	-0.179864878731941	0.0841278015874371
R17K,K76Y,N124E	1.14597234497961	0.100514408125302
R17K,L38W,P69D,W103K,Q117R,D127V,V142N	-0.0282426182324206	0.1152062474547
R17K,L60Q,Y68C,K76A,V148K	-0.217562180195584	0.110120063079188
R17K,P73L	-0.351841832122617	0.199734682943614
R17K,V25M,E54G,K74R,Y134C	0.317452834849686	0.18797727483106
R17K,W41R	-0.19301690686807	0.0699487562126743
R17K,Y134C	0.412192532156008	0.106924252509452
R17M,D67G	0.298081550718968	0.140346582139394
R17M,F22L,I45T,P84L,I109V,G115V,I125T	0.156813298072011	0.167623925790273
R17M,K74N,Q111E,G115V,Y137D	0.632937783603616	0.132279072630586
R17M,M39T,N40S,K101R,K110T,Y137N	0.409552927816438	0.23283800718796
R17N,F77N,I112R	0.112481809639877	0.10594076361162
R17P,N37I,A133G	0.0192163936667994	0.110558934990264
R17Q,E42A	0.175759360496403	0.102991367552675
R17Q,I112C	0.107173767009782	0.0999767173369358
R17Q,K74P,I109C,A129L,R141P,S158M	0.16155889658765	0.115893413520195
R17S,N121S,Q126R,I136A	-0.320486411225984	0.159166606968422
R17S,V86A	0.0500706166663288	0.119306031401873
R17T,G47R,Y68E,K74T,S95R,G115N,I136R,R149Q	-0.189601399896912	0.045992279036736
R17T,K18R,N31C,F82D,E122D	-1.18072973844895	0.362094005212986
R17T,P32L,N121Y,E145G,R147G	NA	NA
R17T,P32L,S70P,R147W	0.209984951913455	0.132717380058618
R17T,Q130K	-0.112372529479386	0.117839450604673
R17V,A106D,Q126H	0.883964759401315	0.144787951167185
R17W,C93S,K101R,A106V,I112T,Q139R	0.445831018363934	0.188487968453338
R17W,D19A,D102Q,T135K,V142N	-0.0425989559534258	0.120127893151502
R17W,I112T	-0.0371739830288257	0.112076165619315
R17W,K110I,E122S	0.106649626913673	0.105316158903692
R17W,K76N,I112T,Q117R,Q126L	0.0759626749814339	0.216718736723053
R17W,L119P	-0.253723897375516	0.10731430887137
R17W,L120A,A156S	-0.520195561408053	0.165482764026091
R17W,L94Q	-0.0127430156188407	0.122984374297783
R17W,P28L,M39I,K76E,V148A	-0.112237764023992	0.0728406129340373
R17W,R104G,E118V	0.231997228707395	0.173471303052493
R17W,R104G,I116M	-0.143801904776642	0.201404901191606
R17W,R141I,V142M	-0.134925454270401	0.118280025533144
R17W,W41R,K110E	-0.0633085896994501	0.172672466423194
R17Y,K30R,P79Q,T135D,N140H,R147G	-0.086184711739006	0.123893369213288
R61C,P80L,R104K	NA	NA
R61D,N121D,N124R	-0.0248294098651077	0.13599968149796
R61G,E78D,S95F,K101E	NA	NA
R61G,E78D,Y87N	-0.355369685063097	0.216546165231384
R61G,I107R	-0.0660282171571413	0.134195859280889
R61G,P69S,E118G	0.434893015359746	0.168693591399888
R61H,E78T,I109W,K110R	-0.397332991877634	0.149179867945155
R61L,L120P,I136T,E145V	0.0833729537117774	0.176690296841849
R61P,K76L,D127A,E143G,K153E	NA	NA
R61P,K76R	1.14468791569257	0.106964088836722
R61Q,F77I,E132G	0.353873061709278	0.105923746154796
R61Q,F77Q,V92A	-0.184604441999036	0.182347502472543
R61Q,F77T	-0.258951099112341	0.153771147397578
R61Q,H83R,I116K	0.208760900557484	0.111080034212626
R61Q,K101T,L114A,A150W	NA	NA
R61Q,K74E,K153R	1.60457009827391	0.0836154594887463
R61Q,K74E,K76S,L81I,K153R	NA	NA
R61Q,M62T	0.714955603253913	0.124408715753988
R61Q,Q117R,K153M	0.00465174651454273	0.209886319717152
R61V,D66V,E122D	0.586749277968447	0.147634734678093
R61W,C75R	0.147095479485671	0.115233666524829
R61W,E98K,N140D,V148I	2.10686610860499	0.142767591963738
R61W,H83L,I136T	0.961699205659857	0.175148010644042
R61W,I112M,V148Y	0.00280493306714863	0.122619484903747
R61W,Y68F	0.43913150958287	0.224716545341353
R8G,A10T,K65R,D102N,N124D	0.330569717913391	0.16765040919859
R8G,A10T,K65R,N124D	-0.0666907628066719	0.122556311665616
R8G,C43S,K65E,F82S,L119H	NA	NA
R8G,C43S,K65E,L119H	-0.0160917245134356	0.0944530234454967
R8G,F82S,L114S,N140I,K146I	0.0497447681188086	0.115407151818815
R8G,G47R,K65Q,I109M	0.224764064718718	0.164144418186314
R8G,H20L,D66G,C138Y,V148L	-0.333238089635443	0.12304878936502
R8G,H83R,Y137C,E143K	-0.257630162064919	0.090265024636356
R8G,H83R,Y137C,E143K,E145G	0.97895888731794	0.133513947616036
R8G,I109M	0.0829989435651938	0.101751283631355
R8G,I112T	-0.211211185005583	0.113910521226927
R8G,K18E,M36I,E54D,P69S,G90W,E122D	0.0268007254709927	0.169730852143899
R8G,K30E,N40I,P157L	-0.0474321525894586	0.158575603470105
R8G,K30E,P157L	0.0152741163070417	0.148655484581611
R8G,K49R,E54G,F64L,Y68N	0.193384335294252	0.129590047013385
R8G,K49R,F64L,Y68N	-0.0559663093877396	0.0993500675607154
R8G,K59R,H83Y,I109M	0.478450513374411	0.179162082035668
R8G,L119V,E122G,Q130P,N140D	0.0367271182298749	0.168066622630702
R8G,N140S	NA	NA
R8G,N37S,L38R	2.02286894195007	0.181870102378346
R8G,N40S	-0.18034004223598	0.247347324663665
R8G,P21A,W53R,H83R,Y137C,E143K	0.13209806558246	0.153028341660065
R8G,P52L,P84L,A106V	0.141734288581473	0.119952220324154
R8G,P73R	0.109383809646019	0.132124338443722
R8G,Q111G,L120A	-0.14619862729523	0.123080235836891
R8G,R13G,C43S,K48R,K65E,L119H	-0.171855949019064	0.183209143055983
R8G,R17G,H20R,F22Y,L114S,Q151R	NA	NA
R8G,T35K,W103R	0.149378736818733	0.147832460692902
R8G,T35M,I96T,L113P	0.115449169488348	0.103319686950636
R8G,V27I,N37S,S70G,L94Q,Q111D,I125V	0.127569089044096	0.238303065353331
R8G,V27I,N37S,S70P	-0.507141302646454	0.167882520928056
R8G,W16R,V25G,N31D,N85S	0.291655258383433	0.136315099863822
R8I,E12D,N85D,C138Y	-0.160594416499289	0.114879704556702
R8I,K14D,V142F	-0.0764452645264135	0.138311408047557
R8K,L97I	0.363534684027056	0.0982397758454828
R8K,P28Q,Q126H,Y144C,R147S	NA	NA
R8K,S71P,W103V,A152V	0.0819835322302159	0.152176016485792
R8S,G34T,D102P,P123Y	0.0382494553733837	0.11684304156346
R8S,I112V,P128T,Q130L,I136V	0.165413727583322	0.18446866999031
R8S,I136V	0.299066397160508	0.149386231282067
R8S,K30E	NA	NA
R8S,K30E,Y134H	-0.0959906457765769	0.111854528813148
R8S,N31Y,M39T	-0.197922012940797	0.0865028530526025
R8S,P46L	NA	NA
R8S,Y68I,L113I	-0.438449656985541	0.133575544591246
S2A,D19A,Y137H,N140D	0.345382075769037	0.166445093149387
S2A,E12V,K30R,W41C,P105K,L113R,A133E,E143M	NA	NA
S2A,E12V,L113R,A133E,E143K	NA	NA
S2A,E12V,P105K,L113R,A133E,E143M	NA	NA
S2A,G3E,S7G,R149P,K154R	-0.591820824506683	0.283497291300323
S2A,G3E,Y68N,E122G	NA	NA
S2A,G3R,K101R,L119P,C138Y	-0.268225060206693	0.212488911843279
S2A,H20R,K48E,F82L,D127G	0.0389131987931353	0.193701073083379
S2A,K18N,K49E,P105S,K153D	-0.295762964840455	0.207855574887242
S2A,K48R,G55S,I125T	0.363052523034039	0.223545107104724
S2A,K65R,E143G,A152G	-0.307935850563963	0.274744357471007
S2A,N37D,L57V	1.09584141198306	0.162912677585641
S2A,R8G,P105Q,I109M	NA	NA
S2A,S7G,R149P,K154R	-0.257923502579637	0.0907055260026469
S2C,R17Q,L38K,K49I,K59G,P72F,P105S,L119Y,C138N	-0.0925411032727321	0.0481602071791108
S2F,V25E,P73S	0.0126285067925326	0.0623506957260875
S2L,A106V	NA	NA
S2L,A10V,P52L,C93R	0.261447635094681	0.153119174549113
S2L,A15S,I109F	NA	NA
S2L,A5V,N31D	-0.0740139508860953	0.055934824533654
S2L,A5V,N31D,L119R	0.221496000144776	0.165275113060409
S2L,C43R,D66E,A106V	0.215250767648364	0.109729285392005
S2L,C43R,T51S,I107F	NA	NA
S2L,C43R,Y134C,E143G	NA	NA
S2L,D102N	0.0121950594706871	0.0706786149193782
S2L,D33G,W41R,P72S,P84S,I136T	-0.257378410718543	0.108359643002256
S2L,D33N,K76E,E98G	0.556291163424686	0.117076011777404
S2L,E118K	NA	NA
S2L,F155S	NA	NA
S2L,G34V,K74R,I125F,K153M	0.515634267670731	0.10994436694329
S2L,G47R,Y68E,K74R,S95R,G115N,I136R,R149Q	0.306747484709215	0.201941195024699
S2L,G56A,S71P,F77L,Q117L,N121D	0.26113488009724	0.140519705577283
S2L,I107N	0.428281065505751	0.310372838414158
S2L,I107T	0.28593239773051	0.175732455361306
S2L,I107T,Q126Y,R147S	0.348385620992853	0.197394099059415
S2L,I107V,E122G,I125T	0.50272368131668	0.217078204630744
S2L,I107V,I112V	0.0490251150744471	0.103445844597195
S2L,I116V	NA	NA
S2L,I4N,K49E,I107V,I112V,E143G	0.45074021646182	0.216868343968982
S2L,K101E,N124S,Q126L,D127V	-0.327705937678135	0.0568411665969936
S2L,K101E,N124S,Q126L,D127V,Y144H	-0.130954056183177	0.144447507575608
S2L,K101R	0.578589042545063	0.202791538113854
S2L,K101R,G115E,L119P	0.520593142975393	0.191702807679186
S2L,K110E,V148A	0.0766290356167689	0.0740042252071496
S2L,K14E,I45L,Y68S,G115E	-0.184528366207352	0.132438236859214
S2L,K154E	0.836286527111594	0.222014906923637
S2L,K18N,P52S,L119P,D127G	-0.132198315279586	0.110466703739062
S2L,K59E	0.167539465632143	0.115006154763319
S2L,K59W	-0.141294409154334	0.151204545755168
S2L,K74E	0.585844157323684	0.114282010146619
S2L,K74R	0.157495084524598	0.100876510298792
S2L,K76C,T91Y,Q111H,C138N,S158P	0.115780960644626	0.113645745383657
S2L,K76E	-0.170342228648729	0.108587950323955
S2L,K76E,S95P,D102E,E122K,E132G,T135A,R147G	-0.00875501915861162	0.159335842590655
S2L,L120P,D127G	0.111248591374205	0.114269771774009
S2L,L38P,R141T	0.246124119315903	0.10195151919406
S2L,L6F,R8G,V86A,I107N	-0.097378277853404	0.0546678803241572
S2L,L6F,R8G,V86A,I107N,Y134H,T135A	0.322889247651892	0.103170338814187
S2L,L6F,R8G,V86A,V92A,I107N,R149Q	0.0682476940308358	0.156428278374967
S2L,M39L,P105L,Q139L	0.613274993375548	0.177421732002425
S2L,N40K,I125T,Q126R,Y134N,C138R,R141S	-0.332654388383597	0.244314255084731
S2L,P46L,I107T	0.105277032025767	0.0998503455045471
S2L,P52L,H83R,P157T	0.00166326730223543	0.154336632617988
S2L,P88R,A129D	-0.220066392356421	0.100836365059186
S2L,Q11R	0.0522810698218482	0.0645713266232045
S2L,R61Q,C75R,K76R,R147G	0.95596764084457	0.208032847779347
S2L,R8G,V86A,I107N,E122G	0.357873461377088	0.105797223327859
S2L,S71P,F77L,Q117L,N121D	1.16518614806132	0.099348788771486
S2L,S71P,T108A	-0.230859455253343	0.173752634555572
S2L,S7N,K30R,F77L	-0.0858526122071777	0.0655887043122396
S2L,S89A	0.227302353276776	0.111637131360643
S2L,S89L,E118H,Q126R,R141G	NA	NA
S2L,S95P,K101E,N124S,Q126L,D127V,I136T,E145V	0.192572509697228	0.148853704627684
S2L,T108S	-0.505803963992952	NA
S2L,T29I,K30E,A44T,N140D	-0.128935185591867	0.105800487422631
S2L,T35S	-0.223920922524363	0.0997166195684948
S2L,V25A,P84S	-0.284241170417224	0.315003619793909
S2L,V27D,S95F	-0.0275317980639292	0.106033537596068
S2L,V86E,E118K	0.448292183058819	0.196734166503917
S2L,W103K,Y137H	0.405296857776072	0.156890211179738
S2M,N37D,C138Y	NA	NA
S2M,R61W,T91I,C93F	-0.108385661906098	0.100094712203925
S2N,A150N	0.953594718722595	0.116117014458079
S2P,A15V,N31D,K65E,N140D	1.21419441888782	0.167125283381466
S2P,A26T,Q139R	0.127317245306946	0.109454580205843
S2P,D19G,T91I,Q111L,E132G,P157S	0.781383072222981	0.112075248543915
S2P,F24S,K30E,K48M	0.237069776488719	0.24222081251912
S2P,F58L	0.772171402704951	0.188600444903101
S2P,F58L,F64S,P128S	-0.440497640239923	0.251416165032516
S2P,F58L,R141G	-0.741876400319682	0.282486601507049
S2P,G47E,D67T,I116A	NA	NA
S2P,H20L,K65E,K74N,A133T,I136V	0.0863162929356838	0.0765915199999101
S2P,H20L,K65E,K74N,A133T,I136V,N140D	2.19265263729815	0.166735310538657
S2P,I116M,E122R,E143G,E145K	0.658052795150306	0.183774895164996
S2P,I116M,E143G,E145K	-0.253717395971043	0.108727164705354
S2P,I4V,V92A	0.129109350651811	0.103287249168998
S2P,K18R,V27A,D100V,L120Q,N121S	0.242791584653927	0.226668723545994
S2P,K59R,I96V	0.749127895727533	0.101058438879556
S2P,K59R,K65E,D66G,V142A,V148G	0.195909857203056	0.225390960521616
S2P,K65E	0.646987957838404	0.100098816419278
S2P,K74E,N85Y,L120P,Q126K,F155L,P157R	1.09617878721494	0.180602974462424
S2P,L9P,C43T,I112K	0.206728728332025	0.138553533796514
S2P,L9P,N37D,P84L,V86M,E98G,D102G,R104G,A106V	2.33697020303689	0.232050087899405
S2P,N121S	0.658682578762313	0.0596636505315307
S2P,N31K,N37S,I96F,E98K	0.526051620596997	0.218610807219592
S2P,N31S,F58L,F64S,P128S,A152V	0.386369236937979	0.136635576546915
S2P,P79T	0.653131015922729	0.119956387774565
S2P,R104G,L113K	NA	NA
S2P,S95P,I109V	NA	NA
S2P,T108A	0.325539224757666	0.110036073428235
S2P,T108A,I112T,A150G	1.43665293633449	0.183289116901492
S2P,T35M,N121S	0.168012405360937	0.151137526877878
S2P,T91I	0.0300308023163751	0.175148431686495
S2P,W16R,V25M,Y87N,N121S	0.345952034276208	0.062631514694389
S2P,W41R,K59R,K65R,I96V,T108I,Q126R,Y137H	0.0789630243902746	0.170653253023535
S2P,W53R	NA	NA
S2R,G3A,F24L,K65E	0.0149067776172421	0.0940353747571053
S2T,C43Y,S95P	-0.427308483044284	0.193944910489334
S2T,C93Y,A106V	-0.045028207449704	0.178195803480307
S2T,E122G,F155L	0.46637847066737	0.192095796121079
S2T,E12D,G55S,E118V,P123G,K146E	0.0986076984605459	0.137296646266183
S2T,E145V	-0.146003517701749	0.295980281518864
S2T,E54G,R149P	0.168074517847417	0.21316737865532
S2T,E99Q,Q126K,A133D	0.361609139913149	0.181122805271078
S2T,F24S,F58S	0.350860723864705	0.201001915955582
S2T,F77L,K101E,T135M	0.101159875229647	0.059982322910167
S2T,F82S,G115E,R141G	0.415930868372962	0.174223054578318
S2T,G90R	-0.142184867199705	0.122632289620038
S2T,H20L	NA	NA
S2T,H20L,D127N	0.322552141102564	0.172819769021102
S2T,H20Y,W41R,D100N,N121H,V148A	NA	NA
S2T,H83R,S89L,G90V	0.00271677837685502	0.0289025715142395
S2T,I109V,I112A,Q126K,A133D	0.33486918317198	0.191453588279951
S2T,K14E,D33N,K49R,L113P,Q139K	0.37930655545508	0.154424894970889
S2T,K14E,F22S,V92A,L113P,Q139K	0.297227398456496	0.121887254881332
S2T,K14E,K49R,I109L,L113P,Q139K	NA	NA
S2T,K14E,K49R,K154Q	1.14064889573235	0.167756919260774
S2T,K14E,K49R,L113P,Q139K	0.0215513334779547	0.0432788971160961
S2T,K30E,A133S,C138Y	0.161668233226727	0.176944532174164
S2T,K30E,I136V	0.208595041029877	0.122351545888603
S2T,K59S,K110T,V142R	0.338235812385689	0.116537794370613
S2T,K65E,L97V,D102V	2.57588722114031	0.148906682015483
S2T,K65N,Q117R,R141G	-0.270952828492668	0.118395677886956
S2T,L38R,K101E	0.176352859395505	0.20036970041122
S2T,L63P,C138R	0.534694427230975	0.21854839404491
S2T,L63P,S158L	0.216500168024339	0.0982754813042405
S2T,L97V	2.16607154435446	0.0803422692556628
S2T,M39K,P79A,K101E,Q130R,T135M	0.391040763863538	0.244474710426144
S2T,M39V,E54G,I112T,D127G,Y137F	0.118231166380178	0.162657852867505
S2T,N31S,I125V	0.0657315278589129	0.110304298791387
S2T,P32H,K49R,M62T,T91A	0.281030527130998	0.0551613538845303
S2T,P69L,N85S,Y137H,Y144H	NA	NA
S2T,P72A,R104W,P157L	NA	NA
S2T,P80S,T108A,A129T	NA	NA
S2T,Q126H	0.274102588673245	0.207840850510049
S2T,Q126K,A133D	-0.120899036142551	0.119342539886947
S2T,S70P,F77L,S89P,V92A,N140D,F155S	-0.35965325567622	0.199748142025264
S2T,S70P,N140D,F155S	-0.104094791441313	0.121327564879865
S2T,S71T	0.897011882307724	0.11856183444705
S2T,S7G,A129G,R147G	0.0434508840260644	0.110744412377244
S2T,S7G,A15V,F77Y,A129G,Y144H,R147G	0.198568613141139	0.198574722650968
S2T,S7G,L63P,Q111L,A129G,R147G,V148G	-0.402659474390511	0.208709534062121
S2T,S7G,T51A,R147G	0.114031034118213	0.157097048113936
S2T,S7N,N31S	0.112368296809285	0.0938703557791499
S2T,S7N,N31S,K110R,Y144C,F155Y	0.204441756736099	0.191522884788252
S2T,S7N,N31S,S71P	0.686940578796798	0.205349702962068
S2T,S95P	0.693655742525351	0.135096561304851
S2T,T135A	0.37415466758487	0.121507799570849
S2T,V25A,A129V	-0.0483156464969043	0.12506670725941
S2T,V86A,S95P,Q126K,Y134H	0.0257306058261463	0.247919039851267
S2T,W103R	-0.399586531971157	0.114393815170776
S2T,W41R,P88T,T108A	0.018844151415441	0.0569446845222836
S2T,W53R,F82L,I112L	-0.107187207843082	0.0977888592341893
S2T,Y137C	0.417816666896321	0.194798601256313
S2T,Y144H	1.27624685302688	0.198463165125053
S2W,A15E,T29R,K30R,K49R,F58P,Y68Q,P80C,L97Q,I109L,E122S,A156F	NA	NA
S2W,A15N,T29R,K49R,F58P,Y68Q,P80C,L97Q,I109L,E122S,A156F	0.0153466107083733	0.115279757475114
S2W,M36V,K48R,K154R	-0.0933437625225529	0.127321102046013
S2W,N85S,V92A	0.0489610306035595	0.072897043124346
S2Y,R8G,C138G	-0.322983020979521	0.12010202466582
S70A,E145G,A156V	-0.0104550504771414	0.113432470571414
S70A,K74E,Q151L	NA	NA
S70C,A133G	0.287529788543702	0.172968367695175
S70C,K76R,L97I,K110R,I112T,L119H,Q151H	0.617427374063285	0.255983940054141
S70C,K76R,Q151H	0.0739024295626467	0.119003444053535
S70F,I109T,F155L	-0.116042808348693	0.153342349600101
S70F,K154R	0.230486927528896	0.104934557937032
S70G,L94Q,Q111D,I125V	0.0355772357311866	0.114040843183623
S70G,V142E	1.52061581977934	0.108926756742228
S70K,I112P,D127V,C138N	-0.358510452355574	0.156791647636811
S70L,Y137H,R141S	0.117852156406945	0.15239209903081
S70P,E118K,P128S	0.195873077395746	0.109572249008646
S70P,E78G,W103C	0.295728436855662	0.15633945034757
S70P,E98V,K110L,E132L	0.274490140141955	0.0990909606366642
S70P,F82L,I112V	-0.123396758556147	0.115878975643114
S70P,I107N,E132G,R147G,S158P	0.221883830317875	0.174957077952943
S70P,K146R	0.967211430319708	0.198816303189625
S70P,N121Y,R147G	-0.11262958451746	0.112586966935455
S70P,N124I	-0.507518935242278	0.209892011843301
S70P,N85S,V86G,E132G,E145G,R147G,S158P	0.372182104260914	0.216918774920612
S70P,P84R	-0.0906403002044899	0.0412184100289973
S70P,Q130R	0.207388423835901	0.111123000628265
S70P,S71P,P72R	0.4848919702012	0.226813033198293
S70P,T108A,G115E	-0.207298938498674	0.120017314201175
S70P,V86E,E98G,K101N,N121S	-0.208819719949109	0.126090400841136
S70P,W103C	-0.0783852681498085	0.106106887587657
S70P,W103R,E132G	NA	NA
S70R,E122L	0.0222259383676951	0.143814695108203
S70T,I107T,S158P	0.635051764553007	0.126638827892394
S70T,I96T	0.90250245870725	0.100795690931141
S70T,I96T,Q130P,Y134C,R141A	0.0795641076230263	0.189170293928389
S70T,Y87N	NA	NA
S71A,A156S	0.59119229075934	0.10334471254599
S71A,N121S	0.492177294936993	0.171846013017663
S71E,F82C	0.0810047932691645	0.18232388286528
S71L,D127N	0.137950086348742	0.125363921519077
S71L,K74T,I109R,E143G	0.104077068780731	0.135229090141838
S71L,L81I,R104I	-0.356978805501059	0.125860284013364
S71L,N121S,F155L	NA	NA
S71L,Q111L,N121S,F155L	0.794103785069372	0.196691596604204
S71M,E78G,Q126R	0.564252143271078	0.116301280093682
S71P,A129G	0.00637625396897273	0.120124211059782
S71P,D100G	1.61287861580129	0.220349439864031
S71P,E118G	0.655535729653206	0.185383935874004
S71P,F155L	0.807701486785727	0.197033299409596
S71P,F82V	NA	NA
S71P,I107A	-0.153329692593388	0.125776562551866
S71P,I107T,V142E	NA	NA
S71P,K76I,N85D	1.46113573006577	0.144184754623237
S71P,L114R	0.109824059178052	0.199211019637428
S71P,L97S	-0.114329542082401	0.112455983979757
S71P,Q151R	0.370147337769492	0.0328447705063618
S71P,T108A,Y144F	0.182585969734613	0.127582871905271
S71P,T91S,K110R	0.293486564270893	0.225444114429388
S71T,D100G	0.281829019533638	0.114841357522608
S71T,K76R	0.242134174294483	0.17668284395521
S71T,P84L	1.17421222586227	0.11010382953783
S71W,V142A,R147K	0.850505978765467	0.0817511150029007
S7C,C43S,V142Y	NA	NA
S7C,D66G	0.249260768940836	0.116646198646192
S7C,E12T,M36V,L57M,M62V,K154C	0.0290240672528972	0.112687720498869
S7C,F77K	NA	NA
S7C,G34D,S95E	-0.0076395332700683	0.141606064195765
S7C,K14A	0.599571665567221	0.129747506247538
S7C,M36S,K59E,I107R,A150D	-0.374867847394374	0.416341195553342
S7C,M62K,I107V	0.485792746334327	0.11375833191637
S7C,R13N	0.0307947436654964	0.135866703164122
S7C,R17N,G55A,Q126G,R147N	-0.275449345898107	0.12086299048718
S7C,R8G,V86A,L119S	NA	NA
S7C,T135A	0.577480632471414	0.102497536605962
S7C,T29A,N37S,M39V	0.531822579115085	0.113478666748125
S7C,V86A	1.06107320404271	0.146003107733028
S7D,R8S	0.245759739338527	0.102418402607407
S7G,A10V,R104G	-0.0564576438724833	0.0884943526820566
S7G,A26T,L60Q	0.0435429097339155	0.102801035054488
S7G,C75G,I107G	0.419707015951886	0.10087061007246
S7G,E122A,E145S	0.0358868404999516	0.110202802523165
S7G,E122D	0.249831320498785	0.085019264150001
S7G,E42G,V148A	-0.283722285859832	0.118094573648323
S7G,F64S,K101E,Q126R,C138Y	0.244112297450133	0.142798849612194
S7G,F82K,T108V	-0.0691369454832805	0.165048269739711
S7G,G115E,D127G	-0.214085247189126	0.139003871896113
S7G,G115R	-0.119675862267662	0.293254597711969
S7G,H20Y,T108A,L119E,Y134C	-0.0569532950809332	0.13676977385604
S7G,I107T	0.366631563989401	0.103638327077785
S7G,K101E	NA	NA
S7G,K101T	0.586433725530784	0.0634311065192436
S7G,K14R,G56N,L63P,F64S,D67E,I116T	NA	NA
S7G,K18E,P73L,W103R,T108P	0.461545367957558	0.152094914984229
S7G,K18S,P28F,G56W,K74E,V86L,L114V,V142L,V148A	0.31286210083855	0.157773896850854
S7G,K65E,I109Q,E122G	-0.149683866582112	0.119515243048131
S7G,K76Q,P123R,V148P	-0.160040851914503	0.117748702725806
S7G,K76R	0.409173759037324	0.0980968693658052
S7G,K76R,Y134N	0.439599058553927	0.165163355872536
S7G,L63G,D67A,R141G	0.278019754487764	0.139898298936099
S7G,L81S	-0.0270537330768359	0.0437487290153434
S7G,N124S,Q130R	0.0962340130565366	0.0826448200400706
S7G,N40D,E122G,K146E	0.384926012953863	0.1196628651988
S7G,P105W,D127V	-0.112738596969364	0.12225030188802
S7G,P52L,P80A	-0.163865149854441	0.10709063661295
S7G,P52R,K74S,L113E	0.0196871179631643	0.124725756064511
S7G,Q111P,Q130R	0.0252253473239617	0.177008775065294
S7G,Q117P,N124S,Q126P	0.0917174579297245	0.192387629680395
S7G,Q117R	0.106280818958704	0.104088010873227
S7G,R8K,P28Q,Q126H	-0.132611684877325	0.102318653977457
S7G,S70F,Q151P	0.279878706418296	0.136844672617978
S7G,V25E,K76E,A106S	0.110463757204072	0.103600576111946
S7G,Y144D	0.164091462710258	0.207783845831979
S7I,E118L	-0.0357190444262829	0.110788195843662
S7I,G34E,R104G,Q126G	-0.380898387029004	0.171052241092615
S7I,P32T,K74V,N85D,R141A	0.544874880359718	0.206809845594696
S7N,D19G,V92A,Q130R	-0.482659853105112	0.152719372648239
S7N,E12G,L57S,E99G	-0.0593967845522077	0.0899197433489879
S7N,F24Y,L119Y	0.826333263818416	0.170179924184829
S7N,K14R,K18R,N31Y,P32S,M36V,N40D	1.18049633823713	0.15398991267126
S7N,K48R,N121S	0.184778292625493	0.157264765751368
S7N,K74H,I109V,Q111L	1.55289274476978	0.128813045553146
S7N,N40S,L57M,I109T,Y144C	-0.10382661018736	0.11503610768788
S7N,P21Q,C93Y,Y137C	0.0724938786360745	0.0633871546543815
S7N,W41R,A156T	0.0867357923419307	0.0856754009279311
S7R,A10G,R17G,L38P,S95P,P157L	-0.158581373104047	0.166627689688826
S7R,C75S,P80L,E98G,K101E,Y137N	-0.269807534925486	0.131862597127449
S7R,D127E,T135A	0.134844952917244	0.118223954331096
S7R,D19G,I116M,N124D,Y134H,V142M	0.30584835249419	0.143251139713165
S7R,D19G,K59R,D66G,N140D,F155S,P157L	-0.112451380674378	0.0559748509102429
S7R,E78V,I112N	-0.0244170500086681	0.122656734387621
S7R,F22L,A133R	NA	NA
S7R,F24S,L119A	0.102145959820705	0.054913872051017
S7R,F64S,N85K,C138R,A156G	0.340717542436912	0.238038457704702
S7R,F77K,E122S	NA	NA
S7R,H20Y,F22L,L60E,D67G,P73M,I112S,V148N	0.122814909644899	0.111988490608138
S7R,I109F,D127R	-0.164711353866671	0.129199022352779
S7R,K110R,N121V,Y137V	0.0253641217410479	0.102954678827437
S7R,K18M,K49E	0.5136488878792	0.128066847611396
S7R,K59R	NA	NA
S7R,K65L,F82E,S89P	-0.0653542273703784	0.121363492553747
S7R,K65L,F82L,S89P	0.105588162985353	0.10651274519622
S7R,L114G,Y134F	0.734666824525826	0.135901649619403
S7R,L114S,S158T	0.373159292076672	0.122566876322927
S7R,L114Y	-0.834178360356948	0.229598742764562
S7R,L119R	0.0994087901179128	0.0900598455448356
S7R,L38P,I116L,P128C,Y134C,Q151R,P157L	NA	NA
S7R,L9H,L63P,R104M	0.343974096409162	0.162352069491625
S7R,N31F,I109T	0.001323476517111	0.185064420996932
S7R,N31S,D67L	-0.0976779473251204	0.0551950880105348
S7R,N31S,K59N,V148H	-0.202198950347502	0.1988124157176
S7R,N40D,C43S,K65Q,S89P,I116V	0.815540395521229	0.20745629040623
S7R,P69E,E122D,Y134L	-0.267278237400499	0.155871861266872
S7R,P69Q	NA	NA
S7R,R13G,D19G	0.427256501803665	0.157363809380932
S7R,R17G,L38P,P157L	-0.338860879513271	0.115972842181873
S7R,R17G,L38P,Q151R,P157L	-0.0580258038317945	0.0664162293910002
S7R,R61H,P73R,Y134H	-0.0404885346023006	0.109718971807451
S7R,R8G,D66Q,I109R,E122R,Y137C	-0.321225600746112	0.221922916908939
S7R,S70G,L94Q,Q111D,I125V	0.0183946993389867	0.0984667160428266
S7R,W16G,L120A	-0.236144530354671	0.137084208915559
S7R,W16R,T35P,W41R	-0.236855518193484	0.130571654423979
S7T,L60R,D67T,F82A,E118M	0.0217673339352281	0.120480140783341
S7T,R13M,P80M,Y87F,I109Q	-0.0234172002178056	0.148053475554787
S7T,T35A	0.247410303481731	0.0385913088845035
S7T,W16R	0.0145334347333176	0.105884119917755
S89E,I116V	1.03906497501056	0.193206242431764
S89L,E145K,F155S	-0.203836493580031	0.173637843197836
S89L,I107T	0.0260459184856173	0.0656050777916458
S89L,K110R	0.54700305533484	0.103417185756507
S89P,D102V	0.704673118053048	0.178826881545932
S89P,E122W	0.100018000712569	0.107580524794517
S89P,I125P	-0.060025949394334	0.0846296272813234
S89P,K110V	-0.318227436836798	0.398802123408171
S89P,L119F,Q126R	-0.226382619877159	0.105601844626352
S89P,P105L	-0.185336716671419	0.168745672374115
S89P,P157R	0.337959194770914	0.127421419611422
S89P,S158P	0.308222138841943	0.130339145181599
S89P,V142S	0.331752350897758	0.111253441071028
S89P,W103K,L114F	NA	NA
S89T,K101E	0.827430662550549	0.0263728575390185
S89W,L114S	-0.314067157584603	0.124018498650914
S95F,D102G,Y134H	-0.389667137708715	0.0987830316061394
S95F,N121S	0.0579174256053973	0.119996691115598
S95F,R141K	NA	NA
S95H,Y134V,N140S	NA	NA
S95P,D127G	-0.0906139652518834	0.113121773556124
S95P,D127V	0.277856636606515	0.112368479522535
S95P,I116V	-0.24361394832717	0.206913120158347
S95P,I125L	-0.332608366526919	0.138536770221159
S95P,I136A,E145G	0.554076414789257	0.107575386215468
S95P,I96T,L114V,I125T	0.179623497935262	0.157423538326135
S95P,K101R,K154E	0.586765993771551	0.235230611085623
S95P,L114S,E122S	0.0390104693912995	0.194884877191232
S95P,L119P	1.20342266942326	0.306041306991764
S95P,N121S	1.80299484579762	0.153920998667839
S95P,N124H	NA	NA
S95P,Q111K,E132G	-0.0415165419900287	0.141189278146534
S95P,Q117H	-0.120743689107705	0.203475847516811
S95P,Q117P	0.108545952130353	0.13286651351264
S95P,T135S	-0.0950459346827147	0.105869211779784
S95R,A106D,A129V,Y137C	-0.0650533804401362	0.102454698949753
T108A,A133E	0.389710129524898	0.218538825432529
T108A,E118K,I125P	0.206728627901	0.17564471455915
T108A,E122I	NA	NA
T108A,E132L	1.47760900130274	0.111917702275851
T108A,L120P	-0.0742694293247955	0.0481026832254058
T108A,Q126H	NA	NA
T108A,Q139L	1.92815781956102	0.131259974523209
T108A,V148I	NA	NA
T108I,I125R	-0.207995286017816	0.172135968737123
T108I,L114S	0.542622933416436	0.0811013152746068
T108I,Q111H	1.37824132130164	0.115654861834308
T108L,I125W,E143R	-0.112946299157643	0.126632948275794
T108L,L114V,A131T	0.556568355153982	0.16634319222398
T108N,N124R	0.338694517056166	0.143069707230327
T108P,A129V,K146R	1.29647817133776	0.195457780926165
T108P,L119P,L120P,R141H	-0.376023285672783	0.117693160520206
T108P,Q130R,C138W,K146G	0.550490142834425	0.152317400786127
T108S,E122C	-0.253153072751868	0.154486323407813
T108S,E143L	0.805638929603559	0.245698790219752
T108S,R147G	NA	NA
T135A,K153R	1.17032429523334	0.130345203640778
T135A,N140D	0.574913560982186	0.0990214773336627
T135A,R147G	0.0227097313076409	0.105858195519663
T135A,Y137H	0.0432471457627735	0.117065987535186
T135M,K146E,F155S,P157L	-0.280393949429225	0.108408330526942
T135S,N140S	-0.272709144671955	0.114139558684345
T29A,C138R	0.517582324319221	0.140293088959971
T29A,C75R,E118C	0.229672690952549	0.100664310181134
T29A,E143V	1.8816559512196	0.141450030809841
T29A,E99V	1.13181814170632	0.151635010455898
T29A,F64S	0.234399495499161	0.113953374831465
T29A,F82P,P105S	0.853093870362696	0.104864174504116
T29A,I109T	NA	NA
T29A,K59I,L60I,P128L	-0.00276754524883947	0.135006455307986
T29A,K59I,T91A	1.37574790017213	0.108301571254005
T29A,K65N,E78D	0.856208407736102	0.12651058212927
T29A,N31D,I112V	0.702081758805562	0.113532429324009
T29A,N40D,S71L,C75R,L113P	-0.581774958341344	0.148135573061847
T29A,P128T	0.572020279665749	0.0841222788529106
T29A,P46S,E54G,K110T	-0.0723136344279036	0.115669564473132
T29A,P69Y,W103L,S158P	-0.0967956640329052	0.117168381001329
T29A,Q126H,D127G	-0.0078924284900896	0.175047027637993
T29A,S71P,E122K,E143V	1.40392155854123	0.156370764702336
T29A,T35A,E99V	1.64935186220498	0.223551539344984
T29A,W103C,I112T	-0.363523979029049	0.135444486275296
T29A,Y87C	0.581387597588975	0.10359739496698
T29F,K110V,I136T	-0.0942366601542876	0.140764715800066
T29I,E54G,F77Y,R104A,Y137C	-0.556417717539318	0.207865154676984
T29I,F64S,L97I	0.417306316692022	0.116735476444419
T29I,I107V	NA	NA
T29I,I136V	0.870315620244404	0.112251834197611
T29I,M36T,K48E,Y87C,L97S,I107V,A129T	0.302459624758426	0.159158893083226
T29I,S70L,D127K	-0.168931288791951	0.13746531558594
T29I,S71P,Q151R	0.352563283352529	0.171255246544997
T29I,W41L,E118Q,K154E	NA	NA
T29I,W53S,L63F,I109V,A133V	-0.0499456410683192	0.0707837269046023
T29K,K146R	1.76761517176001	0.125149583924882
T29N,T135P	0.342559553195845	0.140744670180746
T29P,K101E	0.148898623239637	0.104220305138421
T29P,K48R,K59N,L81T,I96T	0.243637008142889	0.203711132657839
T29P,K59M	-0.738566609697278	0.220161363099313
T29P,L63P,N140D	-0.0378457898776627	0.107570803402915
T29P,M62T	0.227291327507179	0.123654357712333
T29P,M62T,F82S	0.139988851328831	0.175556484598462
T29P,T51A,P80L,D100E,A106P,I125F	-0.245386833626499	0.112547352447068
T29R,V92A	0.303357884818255	0.178935202798513
T29R,W41R,N85D,E143V	-0.166895697135051	0.181314381109114
T29S,E118G	NA	NA
T29S,N85D,I112T,I125T	0.294317190862849	0.186742972473116
T29S,R104S,E143Q	-0.323697071373617	0.128557449966134
T29S,S71T,R104K	0.112942044423063	0.148462364048753
T29S,T35A,P79Q,N124D,R147M	-0.128152572844771	0.122991194760346
T35A,A44T,I45V,K76R,S95T	-0.0539030379143803	0.121136648951462
T35A,C93W,Q117R	0.144039056528425	0.218161928410414
T35A,E118G,N121D,T135A	0.0226694593479001	0.118633661445827
T35A,E98G,E122D,Q130R	0.435191088500951	0.235533894383949
T35A,F155S	0.572955964395492	0.178259522235517
T35A,F77L,Y87C	0.073345184717693	0.101731384986361
T35A,G55K,P88R,W103R,T108I,E122R	NA	NA
T35A,H83C,K110L	1.35341391103302	0.113221393777457
T35A,K76R,S95T	NA	NA
T35A,M36K,K101E,R141S	0.55867431757112	0.149302392080518
T35A,M36K,R141S	0.0467258306058449	0.0625574595780045
T35A,M62V,N85Y	-0.117924485551544	0.103273050332863
T35A,N37Y,F58S,K101E	-0.0305889974617667	0.0417945851372706
T35A,N85K,R104G,R147G	0.259575921438326	0.20380593585424
T35A,Y137N	0.0258275446702953	0.10477808006201
T35A,Y87N	0.346104239846777	0.171681837051478
T35C,L114K	-0.167934072939792	0.132812789613057
T35I,K48M,V142E	-0.333476777503778	0.121429906450476
T35K,P80S	-0.292624377345378	0.145133797726852
T35K,P84L	1.50451366320765	0.106971606542505
T35K,W103R	0.154151167394235	0.118701934120243
T35M,D66E,V92A	0.0455606972492544	0.0942940920494143
T35M,F64S	0.285418847039955	0.0531449200487938
T35M,F77I,R141S,K146R	NA	NA
T35M,L119P,C138G,R141S	0.0689466074844982	0.211359926606006
T35M,L38H,P69L	-0.125181874488348	0.109258808747688
T35M,L97S,C138Y	-0.134761648530911	0.102985368767038
T35M,N37S,F64S,C138G	0.231335249132498	0.207803441925593
T35M,N40T	NA	NA
T35M,R104T,Q117M,V148T	NA	NA
T35M,V148D	-0.215247343675152	0.103030769703921
T35P,C93S,I112L	-0.267539316829093	0.166663657663515
T35P,D67G,L113Q	-0.0770570475124805	0.135274544781957
T35P,D67N,N121L	NA	NA
T35P,I45T,P105V	0.363280847197888	0.150570162094863
T35P,K49R,W103S,N124K	0.0407403003116769	0.153875986232228
T35P,L63N,D67A,L113R,A156S	0.184832654089701	0.11653744833438
T35P,N121Y	0.0895462915074281	0.103909022824996
T35P,Q130L	0.919807010541266	0.162971515730337
T35P,Y134L	-0.036063571804358	0.10915789622176
T35R,I45L,R61Q,K153M	NA	NA
T35S,A131V,A156V	0.421782228419395	0.0633985451218403
T35S,E118G	0.590194860349958	0.112290057387104
T35S,E42Q,D66W,I136M,R141S,V142L	-0.12501245037339	0.148843146528431
T35S,H83L,R149P	NA	NA
T35S,I107N	NA	NA
T35S,I45V,P46L,F155Y	0.186335997756725	0.104599193596698
T35S,K153R,K154E	NA	NA
T35S,L113H,Q126P,C138F	NA	NA
T35S,M36I,K65N	0.69750175848504	0.104620412321732
T35S,M39V,I96V	0.767496554701148	0.0370047991949594
T35S,M39V,I96V,P123R	1.50382954779971	0.120196127845415
T35S,M62I	0.508108323450214	0.239817908422663
T35S,N37D,K153M	NA	NA
T35S,P79H,W103I	NA	NA
T35V,F58S,D66Y	-0.174482657506952	0.0545629910452707
T35W,R147E	-0.214400990908169	0.123428477165016
T51A,E54G	-0.294065874537619	0.110940146272147
T51A,E54G,Y68H,D102V,I109F,E132K	0.178104340954138	0.129471195071296
T51A,E78G,I116M,Q130H,Q139R	0.211641732072342	0.254890740428063
T51A,E98G	NA	NA
T51A,F64S,P84L,W103C,T108A,Y144H	0.148355553855621	0.2437671188879
T51A,F77S,G90R,L94Q	-0.071725444436061	0.131713719116524
T51A,H83R	-0.0604563466210103	0.186284531008206
T51A,I96T	-0.300397018670326	0.120058493905202
T51A,K76N,I107F	0.704316692788306	0.127978504399805
T51A,L119V,T135A,A150S	0.1479648918146	0.118947353467268
T51A,L60N,F77I,D102V,L113R	-0.171622807415409	0.109346637045493
T51A,L94Q,P105Q,D127G	0.115156149917796	0.215860111591644
T51A,N121D	0.0433348922547364	0.0455452800883317
T51A,N140D,E145G	-0.366444991432165	0.124946069518934
T51A,P128T,T135S	-0.0247507583809487	0.134995257332496
T51A,P52Q,D102G	1.11108702860788	0.0986942873727263
T51A,Q126V	0.0686551485930572	0.121808909397804
T51A,V92E	-0.13431096473513	0.120256895036647
T51D,L114Q,A133T,E143T	-0.0213336838036036	0.108208768717453
T51I,F82S	0.0414070824844401	0.126226252381391
T51I,I107R	NA	NA
T51I,L97S	NA	NA
T51K,I112L	-0.112309139566531	0.130523394502876
T51P,D127P	NA	NA
T51P,R61S	-0.107252647651286	0.135932863693148
T51S,F58Y,F82S,E98G	0.425366736861105	0.144049321755965
T51S,F82S	-0.00815414664103472	0.115447488933135
T51S,M62V,E122V	-0.0725959043202473	0.108595653641833
T51S,Q126R	0.700138180712846	0.132591945572552
T51S,W103R	-0.016988101755519	0.253870270419384
T91A,D102G,E118S	1.36556691194207	0.122948629482263
T91A,L119H,D127N,F155L	-0.0377387788363016	0.135099769748711
T91A,L97S	2.95877010967011	0.11719530794135
T91A,N140I	0.0425653114768934	0.06572104089973
T91A,P105R,L120S,E145G	0.0116442147699868	0.139073421697014
T91A,Q126R	NA	NA
T91A,R104S	1.72321843231144	0.110528564719235
T91A,T108A,L120P	0.14850232392178	0.203926035533629
T91A,T135S	1.62072252421043	0.121102449936063
T91A,V142E,V148A,K153R	0.719936122758697	0.098677047830077
T91I,Q111L,E132G,P157S	0.28124931085387	0.112835713985787
T91I,Q139R	1.88914243988215	0.182963134145539
V142A,F155L	0.118017308483939	0.111923707367854
V142A,K154E	0.539465569764789	0.18439350091206
V142A,Y144S	0.00415985180207471	0.112534585007881
V142E,E143K	0.448339862505482	0.164587826109684
V142G,E145G	0.00496269930533369	0.122802333124532
V142G,K153Q	1.45235072731473	0.188830785380354
V142L,K146R,V148A	1.56859366011155	0.12606399181245
V148D,A156V	-0.172528478540798	0.11994505755174
V25A,C93S	-0.233071170643464	0.10335387430873
V25A,E54K	0.159840921640106	0.125773937537271
V25A,E78G	0.263732075652973	0.124391312742192
V25A,F58S,N85T,I96T,I116T,A152T,A156V	-0.192268996530301	0.107648185407556
V25A,G56S,P105L	-0.0696681444975875	0.134017345076705
V25A,H83R,Y87N	0.166971426407402	0.0230822014868418
V25A,K48E,K65N,F82S,C93S	NA	NA
V25A,K48R,F82S,L120P	NA	NA
V25A,K48R,M62V,F82S,K110E,I112V	0.301439920052287	0.218230980742657
V25A,K48R,S71P,C75F,N121S	-0.0207900650705479	0.0573337075878018
V25A,K59E,P73R,L120P	0.0666596584535388	0.10822528810326
V25A,P73S	-0.117276696996156	0.106385287787303
V25A,S71P,L81S,I136E	-0.129734293775259	0.147900951589505
V25A,T135S	0.619255940945953	0.121118342993547
V25A,T29A,F82Y,I107T	1.04974637518033	0.193381930540273
V25A,V86A	0.250214708299609	0.125408904478802
V25A,W41R,P128A	0.439137640809101	0.220672761943193
V25A,W53R,Q130R,Y137H	NA	NA
V25E,D33E	-0.0669905778930205	0.0803406206547627
V25E,F82S,P157S	0.111666095830796	0.0473682698787679
V25E,L60T,K76T,I109S,Q130L,Y137C	0.197538610037393	0.163674714032958
V25E,Q130L	0.381258127989725	0.100456111887122
V25G,M36L,C43R,E54V,F58Y,W103A,N121S,I125L	0.343873792143803	0.109962030228979
V25G,Q117R,N124Y,E145G	0.220107095267792	0.0498705004690052
V25G,R61P,K110I,N124D,V148I	0.243146424645699	0.138716752879983
V25L,E42G	0.528210116869291	0.099445277841623
V25L,I107N	0.448279519775085	0.170379660994685
V25L,I96V	0.436897542107728	0.146951774963038
V25L,L38P,P80R	-0.185082057272158	0.10124555056501
V25L,L38P,P80R,N121D	-0.114094203245058	0.137201536027693
V25L,M62L,T135A	0.268474700337113	0.103162668960399
V25L,N37S,K65R,P84S,E99D	-0.111548112171791	0.227260716755351
V25L,R141S	0.209044401321333	0.140634063138263
V25L,T91A,D100G,N121D,Q126R	2.09541606175318	0.17037865718051
V25M,A44V,E118D,Q126H	0.235417674739304	0.106455671146598
V25M,C43S,I96L	1.35239120830384	0.204046047148011
V25M,C43S,P52Q,K59N,S71N,I109V	NA	NA
V25M,F77L,I112T,Y137F	0.0429536559117817	0.132891671807254
V25M,K48E,F58L,I109V	-0.398916924364233	0.161098830607256
V25M,K48E,F58L,I109V,I125T,E132K	-0.00495390454575809	0.19733418936947
V25M,K48E,F58L,P69S,I109V	2.03013695793277	0.17230826591231
V25M,L38P	-0.191738970724457	0.16293436443593
V25M,M36T,E54V	1.0407020521901	0.109699272595777
V25M,Q111L,E132V	-0.240538785406951	0.210403351155851
V25M,Q130P	1.0731203996011	0.183060489981799
V25M,T35R,L114S	-0.234567989140926	0.157611567944384
V25P,M39I,K65L,L81V,D127N	-0.0319610591996346	0.0587950294901399
V27A,D66G	-0.253863592579743	0.100512488778204
V27A,E118D,I125T	0.921671389704345	0.165217882207495
V27A,E42G,K59E,D66G,F77Y,L81F	0.00648133986391847	0.0639212679560504
V27A,E42G,K59E,K146E	0.373307382697031	0.186377467961873
V27A,F155L	0.205495912027279	0.0552847115407726
V27A,F58L	-0.0773186956154369	0.110538829945613
V27A,F77R,K110L	-0.0598575713196359	0.102936197742876
V27A,I45T,E98K	1.37739157090793	0.16460522385714
V27A,K110R,Q117R,N121F,N140S,E143G	0.111260952315517	0.199730728673024
V27A,K110V,L120S	0.642396535696762	0.165408684239567
V27A,K153R	0.505820142810323	0.117898132444816
V27A,K65R	0.872074359832028	0.113500911998049
V27A,K74D,I112R	-0.311833025718123	0.177446141623758
V27A,L120P,D127A,P128S	0.918677123100638	0.11746704278856
V27A,M36V,T51A,E54G,L120Q,K146R	-0.0533705611887481	0.201724369731097
V27A,M39T,E118W,L120P	-0.0856664594535232	0.14088613345199
V27A,P32G,K59E,P84L,L119T	0.126028036098964	0.110877939612964
V27A,P72L	NA	NA
V27A,P88H,G90W,I136M,R147G	0.0917158913017191	0.128384664331067
V27A,Q117R,N140S	NA	NA
V27A,T51L,Y87D,L113G,A129P,V148N	0.07642797641195	0.120731361578118
V27A,W41R	-0.20257238197108	0.113932108026657
V27A,Y87H,R104P,V148A	-0.276076252056428	0.165125293916383
V27D,D102G	0.342056352842764	0.247841472377699
V27D,D67L,L114F	0.765377323194274	0.200901466121587
V27D,E118G	-0.478337738641089	0.13902905335455
V27D,I125C	-0.169377436723821	0.133154730255979
V27D,L38P,P52Q,N121D	0.112864824843389	0.134777626849723
V27D,N124D	NA	NA
V27G,K76E	-0.344227721753892	0.199132643513279
V27I,E118R	0.946294390754189	0.212412970330308
V27I,E78Q,N124K,A133T,E143V	-0.061519063671914	0.0795396638860146
V27I,G55E,T108I,A156V	NA	NA
V27I,L63P,C138R	-0.123795909970804	0.118888113804413
V27I,P80V,L114S	0.0642963757103637	0.15260833492129
V27I,S95Y	-0.721357687988504	0.213386900947936
V27L,P72S	1.16205483172931	0.144934958211078
V86A,A133E,R147K,V148A	0.574030650515542	0.1117598041642
V86A,C93S	NA	NA
V86A,E98G,Q117L	0.145274954079452	0.201383760640125
V86A,I107N	NA	NA
V86A,I116T	0.129176952815641	0.104881340382308
V86A,I96V	0.527526085718357	0.104547320205052
V86A,K110R,V148I,P157H	-0.00620476661589747	0.111452147193209
V86A,L113H,K153F	0.597476499402006	0.181562605419761
V86A,L113I	1.2354520945185	0.204934220541779
V86A,L113M,E143K	-0.0997094873489858	0.110560063056106
V86A,N121Y,R147G	0.485478664522905	0.162261737234692
V86A,Q117L	0.110777224187869	0.0976429886046633
V86A,S95P,Y134H	-0.219337599968982	0.106900367827388
V86A,W103R,I116T,F155L	0.217973744248496	0.197771479009692
V86E,A133G	-0.0251072408327328	0.215434500370642
V86E,C138R	-0.271353009298195	0.0652793494227234
V86E,V92A,D100N,K146E	-0.0580568772759225	0.0999106405488117
V86G,L94P,E145G	-0.0779061401029703	0.188545457030698
V86I,S95F	-0.109009214771809	0.1252460326808
V86L,D100G,W103R,Q117H,N121D	-0.269433005822143	0.121794559761239
V86M,A129T	-0.229046793767101	0.0804631311191517
V86M,F155S	0.100159262906997	0.122569218518678
V86M,I107L,E122R,E132D,T135A	NA	NA
V86M,N124K,T135A	-0.0545395513570414	0.104924264912926
V92A,A133S,I136V	0.0938875330218828	0.10840597737161
V92A,C93Y	-0.0112126718503195	0.116214291726186
V92A,D102G	1.0966088420147	0.0757819245022931
V92A,R104G,I112T,E122D,P157A	-0.39419750034855	0.230551790063421
V92A,R149Q	0.023305526708295	0.101525277909521
V92E,E132G	NA	NA
V92E,I112R,Q126L,I136V	0.251379443870868	0.108021561687559
V92E,I116V	1.54982492901755	0.197119895772816
V92E,I96T,K110N,I136D,R149Q,F155L	0.754697353074152	0.220866825504112
V92E,K110S,I136D	0.213412965617646	0.109686291588329
V92E,R147W	-0.0714995105875114	0.0432281444084409
V92G,I125T,E132K	-0.192435039287609	0.130920722843923
V92L,K101E,E145V	0.206742558123572	0.113381329313817
V92L,R104W,I107T,Q126P	-0.22069666594214	0.24379131285653
W103A,I109N	-0.0958841710547104	0.174812660828482
W103C,A129T	-0.0841541584448471	0.110156064945006
W103G,A150V	-0.136946725510473	0.145278101233413
W103H,S158P	0.128279254952957	0.14863054574641
W103I,C138Y,V142E	-0.130588674095843	0.151159796129925
W103I,Q117A	0.150324300992373	0.12028849171134
W103L,L113T,V148M	0.333828800468075	0.120217444262131
W103R,E145G	0.0337554399437075	0.124259460443894
W103R,K153R	-0.0220901033855604	0.055199129835134
W103R,N124F	1.34258664233778	0.22401133445524
W103R,Q111F,A156V	-0.434813961100186	0.173394255967644
W103R,R141T	0.0741823071336348	0.235384927752318
W103R,T135A	0.114072667653167	0.182010133526227
W103R,Y144S	0.0416342512285282	0.103066261191814
W103S,P123C	-0.144036842878214	0.171091200110448
W16A,H83R,A106N	-0.0271138208700417	0.0744687351822984
W16C,I116V	0.565320567402392	0.102208827823771
W16C,V27F,E118V	NA	NA
W16C,V27F,E118V,C138R	-0.0870432104688158	0.127859567183248
W16E,E143S	-0.314275143146764	0.130316685047655
W16E,N37S,L57I,D66Y,K76E,L94T,Q126R,Y137F,F155H	-0.309184199869562	0.152373298032495
W16E,N37S,L57M,D66Y,K76E,Q126R,Y137F,F155H	0.297740717052077	0.163879173912517
W16F,K30D,K59R,K110E,Y144L	0.0895408201691437	0.112584495648062
W16G,I45T,F58L,E99G,I109T	0.113752598396684	0.125197152358676
W16G,I45T,N121Q,I136W	-0.059901917541748	0.0667990982520607
W16G,K49R,L94P,E145G	0.244585149093108	0.179654696192378
W16G,K65E	-0.426708904805755	0.264462278909243
W16I,K76R,I109M	-0.266808117886159	0.148793535435808
W16I,L60T,K76T,I109R,Y137C	-0.115067966744132	0.13545894397084
W16I,N40S,F77L,I107T	-0.530418770341541	0.182527387427372
W16I,T51S	0.466895562593227	0.115655002121551
W16K,N37G,G56D,E118S	0.42736481069897	0.116660700882383
W16K,R104S	-0.0617810469651735	0.111051968456243
W16K,T29P	0.105115960931914	0.116931220799821
W16L,F58S,C75F,K110I,N124A	-0.370154364900152	0.141927374497025
W16L,G34T,E122G,P123I	-0.0637643437133883	0.113614828194921
W16L,N121R	0.245590868861503	0.136047673582936
W16L,N31H,V142I	0.436552598482737	0.0577607189931155
W16N,D33T,C43K,L57S,Y68D,L113S,A131W,V142Y,S158I	NA	NA
W16N,I136H	NA	NA
W16N,K48E,E54A,P123L,Y137I	0.157257728300571	0.157189995725557
W16N,L113H	0.0251420250420583	0.106528129578368
W16N,L120P,A150P,F155L	-0.0188931056255758	0.111012509781655
W16N,P88L,I107L	0.226165585873316	0.108573555490358
W16P,D100G	-0.0313078532954628	0.049426503123119
W16P,M36I,L63P,K74H,W103V,E122K,Y134R,R149T	-0.0597529655983616	0.122344919447247
W16P,V27A,L57G,P69Q	NA	NA
W16Q,F64S,K76Y,N85K,C138R,A156G	NA	NA
W16Q,K76Y	0.0344721967292799	0.0656377123582267
W16Q,N31A,G56S	NA	NA
W16Q,Q111T	-0.0899423132563785	0.0634947789739014
W16R,C43Y,G90R,L97S,K110R	2.72145753352184	0.210955918343465
W16R,D127A,E145R	-0.117402835637918	0.106692415360902
W16R,D33G,N124S,D127A,E145R	0.12679908276939	0.164589600245704
W16R,D67N,Y87C	-0.338643776796329	0.126714946126006
W16R,F24L,K65E,N140D	0.154091960354957	0.225775995346618
W16R,F64S,Y87N,P128S,Q130R,K154E	-0.283352093558639	0.148394703341173
W16R,F77S	-0.0256102007254745	0.171305245376738
W16R,F82S,Y87D,I107T,E145G	0.332574096594502	0.153360535796958
W16R,G23D,L57S,F82Q	0.00884931835066212	0.0545520756798342
W16R,G34N,E42K,F77H,I96T	-0.404063102930947	0.21318696794897
W16R,I107F,I112T	NA	NA
W16R,I107T	-0.125614676182968	0.0814152626439974
W16R,I45T,W53C,S89P,L94Q	0.0390268325633941	0.125205750940672
W16R,K101W,I107L,Y144S	0.181668087350352	0.118888440503707
W16R,L119P,V142A,K154E	NA	NA
W16R,L94P	-0.0921913848169389	0.122758737280454
W16R,L97I,L120P,Y144M	0.149564246730962	0.151195978625236
W16R,M36I,L63P,K74H,W103V,E122K,Y134R,R149T	0.236937808124902	0.177634627987901
W16R,M39T,K101R	0.363647604840025	0.169008768800047
W16R,M39T,K146R	0.956088560820619	NA
W16R,M39V,K76R,Q111E,V142G,A150V	0.932766245850581	0.145177590644695
W16R,N140D	-0.00933923692592435	0.0989285359588131
W16R,N31H,Y87C	NA	NA
W16R,N37D	NA	NA
W16R,N37D,K59E	0.942963302949873	0.184405223999018
W16R,P28I,P73Y,K110E,L120R,Y137S	0.47474787753253	0.146249753211587
W16R,P28T,F64S,Y87N,P128S,Q130R,K154E,F155L	0.188664236245722	0.203368512776874
W16R,P46S	-0.184506504439414	0.0831548784938683
W16R,P73S	0.388766696560393	0.153853128825323
W16R,P79F	0.287754911919124	0.117292844602905
W16R,R149Q,A152P	-0.0591849877588709	0.105365551131091
W16R,R17G,V25L,N37S,P46S,K48R,Y87D,T108S,I109V,F155S	0.356687341937337	0.171401295292961
W16R,R17K,E98G,T108S	0.58760328313518	0.132426509405601
W16R,R17K,T108S,E145G	0.105453978005993	0.0647729458990353
W16R,S71T,D100G,D127A,E145R	0.475273362629561	0.14424742958112
W16R,T108S,E145G	-0.6329292493791	0.347074626081099
W16R,T35M,C75P,W103H	-0.569423307133247	0.166472235335889
W16R,V25G,N31D,N85S,N140Y	-0.323948082066673	0.0983288721693591
W16R,Y68C,V86E,A129S	-0.138685622414538	0.223586777403429
W16R,Y87D,T108S,I109V	0.211416206524624	0.128398858579656
W16S,N31K,N40D,K74S,L81I,L119V	0.320973015496	0.122424356700044
W16S,P46S	0.202532879696259	0.142988510285927
W16S,P88L	NA	NA
W16T,E122G	0.1810074709358	0.128192921924884
W16T,L60K,R104K,A133V	-0.363321750881805	0.202638692853
W16T,P28I,P73Y,K110E,L120R,Y137S	-0.231705112198969	0.110383519448116
W16T,P28S,R104W	-0.0789486385751428	0.103531031671987
W16V,K59N,G115R	0.179157775930396	0.124513403642788
W16V,V25M,V27A,H83P,A106S,L120N,D127A	0.0968313226784413	0.127469512041072
W16Y,A133S,F155L	NA	NA
W16Y,K59N,C75L,W103R,E122G,I136L,K154S	0.489046527363896	0.0994531551986441
W16Y,L113A	-0.238885742345359	0.139760781409735
W16Y,N121G	0.180366421295549	0.117426812091766
W41C,F82L,N121D	-0.112989624655897	0.113810227638445
W41C,K48R,F64I,D100H,I112T	0.177137695865912	0.0531751489522533
W41C,Y68C	NA	NA
W41G,C93R,R141S	-0.099644299327047	0.0692667157548782
W41L,D67V	NA	NA
W41L,R104K,I107V	0.190157651333086	0.156673366852845
W41L,Y68G,E98V,I107L,R147V	-0.499189209973705	0.245509910859742
W41R,A150T	0.0200252378348173	0.108298892835709
W41R,C75W	0.0169982795250354	0.0854742385978809
W41R,D100E,I107F,Y137L	0.0209893767404858	0.106533368702201
W41R,E122G	0.0700500271862061	0.134043527957962
W41R,F82L	0.0500198141732404	0.0839686842409661
W41R,G47R,P73A,E122C,A150L	-0.103935867807998	0.113371626387303
W41R,G56A,D102G,P105S	NA	NA
W41R,I107F	-0.178621834148677	0.220402386632134
W41R,I107T	-0.448862795340411	0.220788149959
W41R,I136T	0.12733165351594	0.116713163395314
W41R,K101E,L114S	NA	NA
W41R,K110I	-0.0780120004307724	0.12047050124172
W41R,K49N,E145K,K146R,A152V	0.877416733465942	0.15544234624236
W41R,K65R,F77L,D102G,T108I,Q126R,Y137H	0.431282487457935	0.120298926600616
W41R,K65R,V92A,K101R,P105L	0.0313974256832514	0.121682022501366
W41R,L113V,K146R	0.0229658312324798	0.187370739817367
W41R,L113V,Q139L,K146R	-0.00607456752267152	0.17528953604091
W41R,L97F,Q111A	NA	NA
W41R,M62I,K65R,K76R,T108I,Q126R,Y137H	0.850462583082216	0.162016639381513
W41R,M62V,N85K,Q117R,Q126R,A150V,A152P	0.26412662544312	0.128398727306528
W41R,N124V,P157S	0.280481369031352	0.111139573715973
W41R,P105T,E118G,P157S	0.151398817362244	0.169950546462894
W41R,P157S	0.393497572172397	0.1186203262021
W41R,P69K,S158P	NA	NA
W41R,P69T,V92I,L119S	0.05196924388712	0.129063198843435
W41R,P72T,E122G	0.142738922766519	0.21279763316184
W41R,Q130L	NA	NA
W41R,R61W	-0.117833842738236	0.140979290268684
W41R,S89P,I136V	-0.20939171754957	0.119124594172336
W41R,S89P,Q111L,E122K	0.0324060741234074	0.123990136054109
W41R,S89P,Q111L,L113P,E122K	NA	NA
W41R,T51I,K74R,P79S,A131P,V148A	0.0857119204313194	0.103455395266077
W41R,Y87C	0.25513472600031	0.102669060653938
W41R,Y87N,L114I,P123V,K153R	0.375109761331722	0.225610092293618
W53C,E78G,E118K,A150V	0.360510851060398	0.200701522613771
W53C,I125A	0.0579586498643554	0.124546581307106
W53C,I125F	-0.166991455640783	0.118970208097417
W53C,R104G,A106G,P128L	0.0534777414085365	0.14693690904196
W53E,L113R,D127E,Y144A	0.21227399789615	0.131737392067946
W53G,A106S,F155I	-0.0171492094866842	0.169494542045716
W53G,E78K,Y137C	0.0714395212048883	0.041236877789001
W53G,I107T,K110E,Q111R	0.177583821813125	0.264739347255003
W53G,K110L	0.605280406169951	0.100504258014466
W53G,M62V	-0.156779020408249	0.123676333604113
W53G,P84R,Y87N,Q139K,Y144F	0.0851514793449826	0.198087170099938
W53G,Y87D,Y144F	0.230089033183308	0.225017885136554
W53H,N121R	0.0224451740233485	0.137612912559834
W53L,K146R	-0.0247814912056511	0.119556079492602
W53L,L63P,S70P	-0.599282702448155	0.113189978841288
W53L,T91A,N140I,K146R	0.364080194204011	0.187127927863697
W53R,D102G	0.265569838694735	0.389321115349708
W53R,E98G,P157L	-0.504897464440632	0.203224891831895
W53R,F64L	-0.177324164103919	0.120758317168222
W53R,F64Y,L81S,N85D	0.141148385961185	0.149300255466085
W53R,F77S,L94P,F155L	-0.214796777484505	0.0992832474027336
W53R,F82R	0.246632199594072	0.107533032862898
W53R,K59N,K74T,G115R,E122G,I136L,K154S	0.280422177519302	0.163532759297664
W53R,K74R	0.115774585429513	0.11735309022434
W53R,K74T,G115R	-0.152198267241212	0.0976614722927275
W53R,K74T,L94I,E132G	NA	NA
W53R,L114A,N124V	-0.561764920598057	0.131376311994829
W53R,L57S,E122G	-0.11464610288827	0.118199967113434
W53R,L63P,K76R,Q111L,K146R,V148G	-0.140526565745235	0.227279305491099
W53R,P72A,E122A	-0.00487692402360728	0.123259637748344
W53R,Q111R	NA	NA
W53R,S70C,P123S	NA	NA
W53R,S70P,I107T,E118V,Q126R	0.254400454071362	0.118197266226936
W53R,W103R,T108P	-0.0270881744844215	0.235000273917027
Y134A,N140I	-0.174749536463381	0.409398384721078
Y134F,V142L	0.163266639144696	0.0596649664774948
Y134I,A150V	0.213430270410927	0.254250326100263
Y137F,F155S	0.963437162081229	0.234138708211288
Y137F,N140S	-0.0097554568136247	0.12525986809478
Y137H,A152S,K154E	0.0614578481475276	0.122261292566339
Y137N,E145G	-0.0543160011986636	0.118301666506962
Y144C,A150D	NA	NA
Y144C,R147S	-0.00241788098688939	0.124133379268758
Y144H,A156T	-0.0700801408701299	0.12148992009452
Y68C,K110Q,Q111L,R147K,S158P	-0.0264804272548397	0.0659300310968104
Y68C,L97S,I125T	0.434552483014498	0.194269062533763
Y68C,N140D,R141G	NA	NA
Y68C,Q126L,R147S	1.45714141470933	0.101283477331822
Y68C,V86E	-0.307552753515459	0.117392163461359
Y68C,Y87H	-0.0398484985914723	0.297168186204264
Y68D,E78D,A106S,F155Y	0.303373325149049	0.121795398421996
Y68D,P80L,E143K	-0.347947738885119	0.121620918590828
Y68D,P80L,T91A,P105Q,E143K	0.126909494743778	0.158580048071688
Y68E,L81P,N121W,I125T,S158P	0.226683543536202	0.120636356731043
Y68H,A106P	-0.276686875578307	0.237888549137337
Y68H,A129T	-0.0389354560386881	0.134258950208007
Y68H,I112A	1.36189407767853	0.109889924004978
Y68H,K74T,D127N,A150E	0.702526827974626	0.207593618326874
Y68H,N121D,A129T	1.51064301089994	0.157944903997549
Y68H,P79E,E145G	-0.179675735352092	0.137157335398004
Y68H,T108A	NA	NA
Y68H,Y87H,L113I,A131G	-0.149813320884389	0.173476391523135
Y68K,A131R	-0.0792358330730681	0.101995486012839
Y68K,I112E,N121G	0.237616083473737	0.111593586734476
Y68N,F77N,C93S,E122Q	-0.143751973291057	0.205724328327892
Y68N,K74P,I125N	0.0689892456116731	0.135646605064119
Y68N,K76A,I107G	-0.0821489593273023	0.11153376791439
Y68P,Q126H	0.0158389730092047	0.123936720929429
Y68R,L120N	0.20231540053816	0.11292857647225
Y68S,E122K	0.221203490593652	0.108177606369499
Y68T,Q151W	-0.0847664896440983	0.11457322725536
Y68V,K101R,E122D,Y134H,E145G	0.430542548470791	0.118817486445523
Y68V,P105A,N121V	-0.153967734279373	0.120332979051421
Y68V,V86A,Q139H,Y144F	0.18107264102587	0.163166757064337
Y87C,L94P,K101E	NA	NA
Y87C,L97S,A129T,E145V	NA	NA
Y87C,Q126R	0.312100475460786	0.112275243101689
Y87C,W103R	-0.135475147402351	0.0674093973638153
Y87D,I109K	0.0612890474373998	0.117759012500704
Y87D,I112V	-0.242045464637832	0.164256562726157
Y87D,P123I	-0.247816355823743	0.12739985280911
Y87D,Q111R,Q126V	0.0342478070431491	0.151059631832615
Y87F,E98G,Q117R	3.31557038295106	0.153348217953055
Y87H,A156T	0.192230688776906	0.11968425460691
Y87H,E98V	0.46742273308634	0.11324357939208
Y87H,E99V	0.240764549706586	0.119270802565667
Y87H,L119P,P157L	0.51158813244559	0.182788795373587
Y87H,P105E,A133P	-0.14256668489114	0.129593735227544
Y87N,A106T,I107N,T108A	-0.241469960300607	0.119111669829427
Y87N,E98G	0.13540892437159	0.13741307175576
Y87N,E98K	1.99838543471313	0.151798269013906
Y87N,N124R	-0.240334028510165	0.107067240089072